Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Debbie K. Ledezma"'
Autor:
Nicole F. Bonan, Debbie K. Ledezma, Matthew A. Tovar, Preethi B. Balakrishnan, Rohan Fernandes
Publikováno v:
Nanomaterials, Vol 12, Iss 15, p 2645 (2022)
Prussian blue nanoparticles (PBNPs) are effective photothermal therapy (PTT) agents: they absorb near-infrared radiation and reemit it as heat via phonon-phonon relaxations that, in the presence of tumors, can induce thermal and immunogenic cell deat
Externí odkaz:
https://doaj.org/article/f06db89ae2b649cfa5eac13fdfffd56d
Autor:
Juliana Cano-Mejia, Anshi Shukla, Debbie K. Ledezma, Erica Palmer, Alejandro Villagra, Rohan Fernandes
Publikováno v:
Translational Oncology, Vol 13, Iss 10, Pp 100823- (2020)
High-risk neuroblastoma, which is associated with regional and systemic metastasis, is a leading cause of cancer-related mortality in children. Responding to this need for novel therapies for high-risk patients, we have developed a “nanoimmunothera
Externí odkaz:
https://doaj.org/article/d8296e22596d4a329718dea04c7adb2c
Autor:
Debbie K. Ledezma, Preethi B. Balakrishnan, Juliana Cano-Mejia, Elizabeth E. Sweeney, Melissa Hadley, Catherine M. Bollard, Alejandro Villagra, Rohan Fernandes
Publikováno v:
Nanomaterials, Vol 10, Iss 1, p 161 (2020)
In this study, we describe poly (lactic-co-glycolic) acid (PLGA)-based nanoparticles that combine photothermal therapy (PTT) with epigenetic therapy for melanoma. Specifically, we co-encapsulated indocyanine green (ICG), a PTT agent, and Nexturastat
Externí odkaz:
https://doaj.org/article/2342f49d17814788bb69c38e23db2356
Autor:
Preethi B Balakrishnan, Carissa S Holmberg, Debbie K Ledezma, Alberto Bosque, Rohan Fernandes
Publikováno v:
Nanomedicine. 17:2159-2171
Aim: To investigate Prussian blue nanoparticles (PBNPs) coated with the synthetic analog of dsRNA polyinosinic-polycytidylic acid (polyIC) for their ability to function as HIV latency reversing agents. Methods: A layer-by-layer method was used to syn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::caf6a3b014235f4df9287eb7d1d0eb88
https://doi.org/10.2217/nnm-2022-0311
https://doi.org/10.2217/nnm-2022-0311
Autor:
Alejandro Villagra, Patricia S. Latham, Elizabeth E. Sweeney, Juliana Cano-Mejia, Eric Yvon, Erica Palmer, Vishal A. Patel, Debbie K. Ledezma, Jaclyn Andricovich, Rohan Fernandes, Preethi Bala Balakrishnan
Publikováno v:
Nano Res
Despite the promise of immunotherapy such as the immune checkpoint inhibitors (ICIs) anti-PD-1 and anti-CTLA-4 for advanced melanoma, only 26%–52% of patients respond, and many experience grade III/IV immune-related adverse events. Motivated by the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3f2595be485b7e1a400f9c7e88c542b
https://doi.org/10.1007/s12274-021-3813-1
https://doi.org/10.1007/s12274-021-3813-1
Publikováno v:
Cancers; Volume 14; Issue 6; Pages: 1447
Photothermal therapy (PTT) is an effective method for tumor eradication and has been successfully combined with immunotherapy. However, besides its cytotoxic effects, little is known about the effect of the PTT thermal dose on the immunogenicity of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e28c1c76a15c315485ee4b0662b896d8
https://pubmed.ncbi.nlm.nih.gov/35326601
https://pubmed.ncbi.nlm.nih.gov/35326601
Autor:
Anshi Shukla, Erica Palmer, Rohan Fernandes, Debbie K. Ledezma, Alejandro Villagra, Juliana Cano-Mejia
Publikováno v:
Translational Oncology
Translational Oncology, Vol 13, Iss 10, Pp 100823-(2020)
Translational Oncology, Vol 13, Iss 10, Pp 100823-(2020)
High-risk neuroblastoma, which is associated with regional and systemic metastasis, is a leading cause of cancer-related mortality in children. Responding to this need for novel therapies for high-risk patients, we have developed a "nanoimmunotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa7ac4e728fae5400c91a40ada383283
https://pubmed.ncbi.nlm.nih.gov/32652470
https://pubmed.ncbi.nlm.nih.gov/32652470
Autor:
Rohan Fernandes, Melissa Hadley, Alejandro Villagra, Catherine M. Bollard, Elizabeth E. Sweeney, Juliana Cano-Mejia, Preethi Bala Balakrishnan, Debbie K. Ledezma
Publikováno v:
Nanomaterials
Volume 10
Issue 1
Nanomaterials, Vol 10, Iss 1, p 161 (2020)
Volume 10
Issue 1
Nanomaterials, Vol 10, Iss 1, p 161 (2020)
In this study, we describe poly (lactic-co-glycolic) acid (PLGA)-based nanoparticles that combine photothermal therapy (PTT) with epigenetic therapy for melanoma. Specifically, we co-encapsulated indocyanine green (ICG), a PTT agent, and Nexturastat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9632f54dc7db54798837028e221d78d2
https://pubmed.ncbi.nlm.nih.gov/31963449
https://pubmed.ncbi.nlm.nih.gov/31963449