Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Debbie J. Williams"'
Autor:
Rebecca V. Walker, Jennifer L. Keynton, Daniel T. Grimes, Vrinda Sreekumar, Debbie J. Williams, Chris Esapa, Dongsheng Wu, Martin M. Knight, Dominic P. Norris
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
The molecular role of ciliary Polycystin-2 (PC2) in cyst formation and polycystic kidney disease (ADKPD) is unclear. Here, the authors identify a PC2 mutant lacking ciliary localisation but with active Ca2+ channel function in mice, that is sufficien
Externí odkaz:
https://doaj.org/article/547e1a8754cb4905b8faf5dab5e28885
Autor:
Daniel T Grimes, Jennifer L Keynton, Maria T Buenavista, Xingjian Jin, Saloni H Patel, Shinohara Kyosuke, Jennifer Vibert, Debbie J Williams, Hiroshi Hamada, Rohanah Hussain, Surya M Nauli, Dominic P Norris
Publikováno v:
PLoS Genetics, Vol 12, Iss 6, p e1006070 (2016)
During mammalian development, left-right (L-R) asymmetry is established by a cilia-driven leftward fluid flow within a midline embryonic cavity called the node. This 'nodal flow' is detected by peripherally-located crown cells that each assemble a pr
Externí odkaz:
https://doaj.org/article/846e1cdd51ad455a997231888bc7b258
Autor:
David W. Dunne, Gary W. Williams, Karl F. Hoffmann, David A. Johnston, Tom C. Freeman, Jennifer M. Fitzpatrick, Debbie J. Williams
Publikováno v:
Molecular and biochemical parasitology. 141(1)
Global profiling transcriptomes of parasitic helminths offers the potential to simultaneously identify co-ordinately expressed genes, novel genetic programs and uniquely utilized metabolic pathways, which together provide an extensive and new resourc