Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Debbie G.J. Robbrecht"'
Autor:
Anke Richters, Debbie G.J. Robbrecht, Richard P. Meijer, Antoine G. van der Heijden, Lambertus A.L.M. Kiemeney, Joan van den Bosch, Britt B.M. Suelmann, Berna C. Özdemir, Niven Mehra, Katja K.H. Aben
Publikováno v:
European Urology Open Science, Vol 59, Iss , Pp 50-54 (2024)
Since 2017, two immune checkpoint inhibitors (ICIs) have become the standard of care for the treatment of metastatic urothelial carcinoma in Europe: pembrolizumab as second-line therapy and avelumab as maintenance therapy. Our aim was to describe the
Externí odkaz:
https://doaj.org/article/4791160529b74281ba980260944fa5dc
Autor:
Henk M.W. Verheul, Emile E. Voest, Hans Gelderblom, Paul Hamberg, Ann Hoeben, Derk Jan A. de Groot, Mariette Labots, Debbie G.J. Robbrecht, Niven Mehra, Anne M.L. Jansen, Wendy W.J. de Leng, Erik van Werkhoven, Paul Roepman, Laurien J. Zeverijn, Daphne L. van der Velden, J. Maxime van Berge Henegouwen, Louisa R. Hoes, Hanneke van der Wijngaart
Flow chart of patients with BRCA1/2 alterations submitted to the study team between September 2016 and December 2019, and reasons for drop-out, rejection or screen failure. Abbreviations: VUS = Variant of Unknown Significance, LOH = Loss of Heterozyg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65097be0eb5d177688ddeb4db508010b
https://doi.org/10.1158/1078-0432.22481003.v1
https://doi.org/10.1158/1078-0432.22481003.v1
Autor:
Reno Debets, Astrid A.M. van der Veldt, Martijn P. Lolkema, Ronald de Wit, Joost L. Boormans, Hans M. Westgeest, Jens Voortman, J. Alberto Nakauma-González, Geert J.L.H. van Leenders, Paul Hamberg, Maureen J.B. Aarts, Rebecca Wijers, Astrid A.M. Oostvogels, Debbie G.J. Robbrecht, Hayri E. Balcioglu, Maud Rijnders
Clusters of peripheral blood CD4+ T-cell subsets in mUC patients with and without a tumor response to anti-PD1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6781afd5d0f87c357e940606d6d0e6bb
https://doi.org/10.1158/1078-0432.22482042.v1
https://doi.org/10.1158/1078-0432.22482042.v1
Autor:
Reno Debets, Astrid A.M. van der Veldt, Martijn P. Lolkema, Ronald de Wit, Joost L. Boormans, Hans M. Westgeest, Jens Voortman, J. Alberto Nakauma-González, Geert J.L.H. van Leenders, Paul Hamberg, Maureen J.B. Aarts, Rebecca Wijers, Astrid A.M. Oostvogels, Debbie G.J. Robbrecht, Hayri E. Balcioglu, Maud Rijnders
Numbers of major T-cell subsets in peripheral blood and expression of T-cell maturation/activation markers on CD4+ T-cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33cf01657b3e9a745096e59a378f8122
https://doi.org/10.1158/1078-0432.22482045
https://doi.org/10.1158/1078-0432.22482045
Autor:
Reno Debets, Astrid A.M. van der Veldt, Martijn P. Lolkema, Ronald de Wit, Joost L. Boormans, Hans M. Westgeest, Jens Voortman, J. Alberto Nakauma-González, Geert J.L.H. van Leenders, Paul Hamberg, Maureen J.B. Aarts, Rebecca Wijers, Astrid A.M. Oostvogels, Debbie G.J. Robbrecht, Hayri E. Balcioglu, Maud Rijnders
Study design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40e4e3dfd5ed3e6d38d3253f32359e1e
https://doi.org/10.1158/1078-0432.22482048
https://doi.org/10.1158/1078-0432.22482048
Autor:
Reno Debets, Astrid A.M. van der Veldt, Martijn P. Lolkema, Ronald de Wit, Joost L. Boormans, Hans M. Westgeest, Jens Voortman, J. Alberto Nakauma-González, Geert J.L.H. van Leenders, Paul Hamberg, Maureen J.B. Aarts, Rebecca Wijers, Astrid A.M. Oostvogels, Debbie G.J. Robbrecht, Hayri E. Balcioglu, Maud Rijnders
Highlighted immune parameters in blood, plasma and tumor tissue from mUC patients with stable disease as best overall response to anti-PD1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b310fb08e7068679564bd8bc7543b59
https://doi.org/10.1158/1078-0432.22482024.v1
https://doi.org/10.1158/1078-0432.22482024.v1
Autor:
Reno Debets, Astrid A.M. van der Veldt, Martijn P. Lolkema, Ronald de Wit, Joost L. Boormans, Hans M. Westgeest, Jens Voortman, J. Alberto Nakauma-González, Geert J.L.H. van Leenders, Paul Hamberg, Maureen J.B. Aarts, Rebecca Wijers, Astrid A.M. Oostvogels, Debbie G.J. Robbrecht, Hayri E. Balcioglu, Maud Rijnders
Transcriptomic analysis of immune cell fractions, T-cell subsets, and chemo-attractants of baseline metastatic tumor biopsies from mUC patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::177fd0b2e2a90a230208835a42b518b2
https://doi.org/10.1158/1078-0432.22482030.v1
https://doi.org/10.1158/1078-0432.22482030.v1
Autor:
Reno Debets, Astrid A.M. van der Veldt, Martijn P. Lolkema, Ronald de Wit, Joost L. Boormans, Hans M. Westgeest, Jens Voortman, J. Alberto Nakauma-González, Geert J.L.H. van Leenders, Paul Hamberg, Maureen J.B. Aarts, Rebecca Wijers, Astrid A.M. Oostvogels, Debbie G.J. Robbrecht, Hayri E. Balcioglu, Maud Rijnders
Immune parameters in blood, plasma and tumor tissue from mUC patients with stable disease as best overall response to anti-PD1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61955b769afb0eab0429ea91f97dad93
https://doi.org/10.1158/1078-0432.22482015
https://doi.org/10.1158/1078-0432.22482015
Autor:
Henk M.W. Verheul, Emile E. Voest, Hans Gelderblom, Paul Hamberg, Ann Hoeben, Derk Jan A. de Groot, Mariette Labots, Debbie G.J. Robbrecht, Niven Mehra, Anne M.L. Jansen, Wendy W.J. de Leng, Erik van Werkhoven, Paul Roepman, Laurien J. Zeverijn, Daphne L. van der Velden, J. Maxime van Berge Henegouwen, Louisa R. Hoes, Hanneke van der Wijngaart
Supplementary Table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::682d1fd9a2218e77908d809143d1cd4a
https://doi.org/10.1158/1078-0432.22480997
https://doi.org/10.1158/1078-0432.22480997
Autor:
Reno Debets, Astrid A.M. van der Veldt, Martijn P. Lolkema, Ronald de Wit, Joost L. Boormans, Hans M. Westgeest, Jens Voortman, J. Alberto Nakauma-González, Geert J.L.H. van Leenders, Paul Hamberg, Maureen J.B. Aarts, Rebecca Wijers, Astrid A.M. Oostvogels, Debbie G.J. Robbrecht, Hayri E. Balcioglu, Maud Rijnders
Proposed mechanism of action of pembrolizumab in mUC patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aec0ef7bfdd6da12e8425e4f2c4f8ed
https://doi.org/10.1158/1078-0432.22482021
https://doi.org/10.1158/1078-0432.22482021