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Autor:
Danielle Fletcher, Paul Moss, Christopher Fegan, Victoria J Weston, Debbie Cronin, A. Malcolm R. Taylor, Tatjana Stankovic, Colin R. Bignell, Belinda Austen, Philip J. Byrd, Azra J. Alvi, Grant S. Stewart, Mike Hubank
Publikováno v:
Blood. 103:291-300
The ATM/p53-dependent DNA damage response pathway plays an important role in the progression of lymphoid tumors. Inactivation of the ATM or TP53 gene is frequent in B-cell lymphocytic leukemia (B-CLL) and leads to aggressive disease. Although the ATM