Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Debbie Claassen-Kramer"'
Autor:
Renske D.M. Steenbergen, Saskia M. Wilting, Peter J.F. Snijders, Florianne E. Henken, Akihiko Ito, Johannes Berkhof, Daniëlle A.M. Heideman, René Overmeer, Yoshinori Murakami, Theo J.M. Helmerhorst, Chris J.L.M. Meijer, Debbie Claassen-Kramer
Publikováno v:
Journal of Pathology, 215(4), 388-397. John Wiley & Sons Ltd.
Journal of Pathology, 215(4), 388-397. John Wiley and Sons Ltd
Overmeer, R M, Henken, F E, Snijders, P J F, Claassen-Kramer, D, Berkhof, J, Helmerhorst, TJ, Heideman, D A M, Wilting, S M, Murakami, Y, Ito, A, Meijer, C J L M & Steenbergen, R D M 2008, ' Association between dense CADM1 promoter methylation and reduced protein expression in high-grade CIN and cervical SCC ', Journal of Pathology, vol. 215, no. 4, pp. 388-397 . https://doi.org/10.1002/path.2367
Journal of Pathology, 215(4), 388-397. John Wiley and Sons Ltd
Overmeer, R M, Henken, F E, Snijders, P J F, Claassen-Kramer, D, Berkhof, J, Helmerhorst, TJ, Heideman, D A M, Wilting, S M, Murakami, Y, Ito, A, Meijer, C J L M & Steenbergen, R D M 2008, ' Association between dense CADM1 promoter methylation and reduced protein expression in high-grade CIN and cervical SCC ', Journal of Pathology, vol. 215, no. 4, pp. 388-397 . https://doi.org/10.1002/path.2367
We previously showed that silencing of TSLC1 recently renamed CADM1, is functionally involved in high-risk HPV-mediated cervical carcinogenesis. CADM1 silencing often results from promoter methylation. Here, we determined the extent of CADM1 promoter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e614da7ecc809d78a02fb0bf22509fb
https://doi.org/10.1002/path.2367
https://doi.org/10.1002/path.2367
Autor:
Renske D.M. Steenbergen, Peter J.F. Snijders, Chris J.L.M. Meijer, Debbie Claassen-Kramer, Denise M. Schütze, Suzanne Snellenberg
Publikováno v:
Snellenberg, S, Schütze, D M, Claassen-Kramer, D, Meijer, C J L M, Snijders, P J F & Steenbergen, R D M 2012, ' Methylation status of the E2 binding sites of HPV16 in cervical lesions determined with the Luminex® xMAP™ system ', Virology, vol. 422, no. 2, pp. 357-365 . https://doi.org/10.1016/j.virol.2011.11.006
Virology, 422(2), 357-365. Academic Press Inc.
Virology, 422(2), 357-365. Academic Press Inc.
Cervical carcinogenesis is driven by deregulated E6/E7 expression in dividing cells. A potential deregulating mechanism is methylation of E2 binding sites in the viral long control region, thereby prohibiting HPVE2-mediated transcription regulation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1159784108edcc2a667a759fc38b7e6
https://pubmed.ncbi.nlm.nih.gov/22137333
https://pubmed.ncbi.nlm.nih.gov/22137333
Autor:
Jillian de Wilde, Renée M Overmeer, Jan M. Kooter, Peter J.F. Snijders, Chris J.L.M. Meijer, Debbie Claassen-Kramer, Renske D.M. Steenbergen
Publikováno v:
de Wilde, J, Kooter, J M, Overmeer, R M, Kramer, D, Meijer, C J L M, Snijders, P J F & Steenbergen, R D M 2010, ' hTERT promoter activity and CpG methylation in HPV-induced carcinogenesis ', BMC Cancer, vol. 10, 271 . https://doi.org/10.1186/1471-2407-10-271
BMC Cancer, Vol 10, Iss 1, p 271 (2010)
BMC Cancer, 10:271. BioMed Central
BMC Cancer
BMC Cancer, Vol 10, Iss 1, p 271 (2010)
BMC Cancer, 10:271. BioMed Central
BMC Cancer
Background Activation of telomerase resulting from deregulated hTERT expression is a key event during high-risk human papillomavirus (hrHPV)-induced cervical carcinogenesis. In the present study we examined hTERT promoter activity and its relation to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c2bc80f5d3fae73dc7968e32c945a7d