Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Debbie A.E. Hendrickx"'
Autor:
Corbert G. van Eden, Jörg Hamann, Jackelien van Scheppingen, Karianne G. Schuurman, Inge Huitinga, Koen Bossers, Elly M. Hol, Debbie A.E. Hendrickx, Marlijn van der Poel
Publikováno v:
Frontiers in Immunology [E], 8(DEC)
Frontiers in Immunology, 8:1810. Frontiers Media SA
Frontiers in Immunology [E], 8(DEC). Frontiers Media S. A.
Frontiers in immunology, 8. Frontiers Media S.A.
Frontiers in Immunology, Vol 8 (2017)
Frontiers in Immunology
Frontiers in Immunology, 8:1810. Frontiers Media SA
Frontiers in Immunology [E], 8(DEC). Frontiers Media S. A.
Frontiers in immunology, 8. Frontiers Media S.A.
Frontiers in Immunology, Vol 8 (2017)
Frontiers in Immunology
In multiple sclerosis (MS), activated microglia and infiltrating macrophages phagocytose myelin focally in (chronic) active lesions. These demyelinating sites expand in time, but at some point turn inactive into a sclerotic scar. To identify molecula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82f2c0caf6c2f60c1ad3c9f9f1b2a45b
https://doi.org/10.3389/fimmu.2017.01810
https://doi.org/10.3389/fimmu.2017.01810
Autor:
Joost Smolders, Jeroen Melief, Miriam E. van Strien, Mark R. Mizee, Suzanne S. M. Miedema, Debbie A.E. Hendrickx, Adelia, Kirstin M. Heutinck, Karianne G. Schuurman, Marlijn van der Poel, Jörg Hamann, Inge Huitinga
Publikováno v:
Acta Neuropathologica Communications
Mizee, M R, Miedema, S S M, van der Poel, M, Adelia, Schuurman, K G, van Strien, M E, Melief, J, Smolders, J, Hendrickx, D A, Heutinck, K M, Hamann, J & Huitinga, I 2017, ' Isolation of primary microglia from the human post-mortem brain : effects of ante-and post-mortem variables ', Acta Neuropathologica Communications, vol. 5, no. 1, pp. 16 . https://doi.org/10.1186/s40478-017-0418-8
Acta Neuropathologica Communications, 5(1). BioMed Central
Acta neuropathologica communications, 5(1). BioMed Central
Mizee, M R, Miedema, S S M, van der Poel, M, Adelia, Schuurman, K G, van Strien, M E, Melief, J, Smolders, J, Hendrickx, D A, Heutinck, K M, Hamann, J & Huitinga, I 2017, ' Isolation of primary microglia from the human post-mortem brain : effects of ante-and post-mortem variables ', Acta Neuropathologica Communications, vol. 5, no. 1, pp. 16 . https://doi.org/10.1186/s40478-017-0418-8
Acta Neuropathologica Communications, 5(1). BioMed Central
Acta neuropathologica communications, 5(1). BioMed Central
Microglia are key players in the central nervous system in health and disease. Much pioneering research on microglia function has been carried out in vivo with the use of genetic animal models. However, to fully understand the role of microglia in ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63e3f6226846544e9000f0b48d39fa7d
https://doi.org/10.1186/s40478-017-0418-8
https://doi.org/10.1186/s40478-017-0418-8
Autor:
Karianne G. Schuurman, Corbert G. van Eden, Inge Huitinga, Jörg Hamann, Debbie A.E. Hendrickx
Publikováno v:
Journal of neuroimmunology, 309, 12-22. Elsevier
Journal of Neuroimmunology, 309, 12-22. Elsevier B.V.
Journal of Neuroimmunology, 309, 12-22. Elsevier B.V.
HLA-DR, Iba1 and CD68 are widely used microglia markers in human tissue. However, due to differences in gene regulation, they may identify different activation stages of microglia. Here, we directly compared the expression of HLA-DR, Iba1 and CD68 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49ec0ce1bc8930b48adab9182066a4a4
https://pure.amc.nl/en/publications/staining-of-hladr-iba1-and-cd68-in-human-microglia-reveals-partially-overlapping-expression-depending-on-cellular-morphology-and-pathology(24699071-f3bb-4c39-863e-c76c045ce1fd).html
https://pure.amc.nl/en/publications/staining-of-hladr-iba1-and-cd68-in-human-microglia-reveals-partially-overlapping-expression-depending-on-cellular-morphology-and-pathology(24699071-f3bb-4c39-863e-c76c045ce1fd).html
Autor:
Marc J. Ruitenberg, Linda V. Blomster, Jana Vukovic, Luis Filgueira, Steffen Jung, Debbie A.E. Hendrickx, Alan R. Harvey
Publikováno v:
Molecular and Cellular Neuroscience. 48:236-245
The olfactory epithelium is a site of sustained adult neurogenesis where olfactory sensory neurons are continuously replaced from endogenous stem/progenitor cells. Epithelial macrophages have been implicated in the phagocytosis of degenerating cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be098c9ada39445fe746cca1a9faa225
https://doi.org/10.1016/j.mcn.2011.08.004
https://doi.org/10.1016/j.mcn.2011.08.004
Autor:
Inge Huitinga, Debbie A.E. Hendrickx, Jörg Hamann, Michael van Draanen, Karianne G. Schuurman
Publikováno v:
Journal of Neuroinflammation
Journal of neuroinflammation, 11(1). BioMed Central
Journal of Neuroinflammation, 11. BioMed Central
Journal of neuroinflammation, 11(1). BioMed Central
Journal of Neuroinflammation, 11. BioMed Central
BACKGROUND: The pathological hallmark of multiple sclerosis (MS) is myelin phagocytosis. It remains unclear why microglia and macrophages demyelinate axons in MS, but previously found or yet-unknown changes in the myelin of MS patients could contribu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3969126a1f594626cd3d20a0e5082dfb
https://pubmed.ncbi.nlm.nih.gov/24684721
https://pubmed.ncbi.nlm.nih.gov/24684721
Autor:
Debbie A.E. Hendrickx, Karianne G. Schuurman, Sabina Luchetti, Elly M. Hol, Corbert G. van Eden, Joost Smolders, Jeroen Melief, Miriam E. van Strien, Inge Huitinga
Publikováno v:
Journal of Neuropathology and Experimental Neurology, 72, 91-105. Lippincott Williams & Wilkins
Vitamin D deficiency has been implicated as a risk factor for multiple sclerosis (MS), but how vitamin D metabolism affects MS pathophysiology is not understood. We studied the expression of vitamin D receptor (VDR) and related enzymes, including 1,2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10aa672599995f0c7023db29f2fa8899
https://pubmed.ncbi.nlm.nih.gov/23334593
https://pubmed.ncbi.nlm.nih.gov/23334593
Autor:
Inge Huitinga, Debbie A.E. Hendrickx, Nathalie Koning, Miriam E. van Strien, Karianne G. Schuurman, Corbert G. van Eden, Jörg Hamann
Publikováno v:
Journal of neuropathology and experimental neurology, 72(2), 106-118. Lippincott Williams and Wilkins
Journal of Neuropathology and Experimental Neurology, 72, 106-118. Lippincott Williams & Wilkins
Journal of Neuropathology and Experimental Neurology, 72, 106-118. Lippincott Williams & Wilkins
Autoantibodies and complement opsonization have been implicated in the process of demyelination in the major human CNS demyelinating disease multiple sclerosis (MS), but scavenger receptors (SRs) may also play pathogenetic roles. We characterized SR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8d84c317c15efd0ff37e3bdb8b148a3
https://pure.amc.nl/en/publications/selective-upregulation-of-scavenger-receptors-in-and-around-demyelinating-areas-in-multiple-sclerosis(421c024a-e239-4130-8f8e-787d4c350c09).html
https://pure.amc.nl/en/publications/selective-upregulation-of-scavenger-receptors-in-and-around-demyelinating-areas-in-multiple-sclerosis(421c024a-e239-4130-8f8e-787d4c350c09).html