Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Debasmita, Saha"'
Autor:
Debasmita Saha, Justin B. Gregor, Smriti Hoda, Katharine E. Eastman, Victor A. Gutierrez-Schultz, Mindy Navarrete, Jennifer H. Wisecaver, Scott D. Briggs
Publikováno v:
mSphere, Vol 9, Iss 11 (2024)
ABSTRACT Candida glabrata exhibits innate resistance to azole antifungal drugs but also has the propensity to rapidly develop clinical drug resistance. Azole drugs, which target Erg11, is one of the major classes of antifungals used to treat Candida
Externí odkaz:
https://doaj.org/article/83e0839b577a446791841693a000dfe5
Autor:
Justin B. Gregor, Victor A. Gutierrez-Schultz, Smriti Hoda, Kortany M. Baker, Debasmita Saha, Madeline G. Burghaze, Cynthia Vazquez, Kendra E. Burgei, Scott D. Briggs
Publikováno v:
mSphere, Vol 8, Iss 6 (2023)
ABSTRACTThe World Health Organization recently published the first list of priority fungal pathogens highlighting multiple Candida species, including Candida glabrata, Candida albicans, and Candida auris. However, prior studies in these pathogens hav
Externí odkaz:
https://doaj.org/article/a97369fb80754a18aa5fd5c711b12837
Publikováno v:
Measurement: Sensors, Vol 24, Iss , Pp 100488- (2022)
Customers' steadily increasing usage of power equipment causes a mismatch among requirements and supply, which presents a growing issue for power generation. Energy management is an essential tool in minimizing large supply-side shortages and boostin
Externí odkaz:
https://doaj.org/article/ba96a786b3194e199a1421e17edfab57
Publikováno v:
Molecular Pharmaceutics. 19:733-748
Glaucoma is one of the leading causes of loss of vision. The problems associated with the marketed formulations of anti-glaucoma drugs are low bioavailability, unwanted side effects, and low patient compliance. Hydrogels are an important class of sof
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9effed382b22c84a377fdb8981eeaa06
https://doi.org/10.1021/acs.molpharmaceut.1c00831
https://doi.org/10.1021/acs.molpharmaceut.1c00831
Publikováno v:
RSC Med Chem
FLT3 mutations are one of the most common genetic aberrations found in nearly 30% of acute myeloid leukemias (AML). The mutations are associated with poor prognosis despite advances in the understanding of the biological mechanisms of AML. Numerous s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a645a7e54c592451ec34aaafa966ac3a
https://doi.org/10.1039/d2md00067a
https://doi.org/10.1039/d2md00067a
Autor:
Debasmita Saha, Lopamudra Giri, Parth Gupta, Rahuldeb Sarkar, Rishikesh Kumar Gupta, Ashish Misra, Kuruba Manohar, Suman Gare
Publikováno v:
Free Radical Biology & Medicine
As hypoxia is a major driver for the pathophysiology of COVID-19, it is crucial to characterize the hypoxic response at the cellular and molecular levels. In order to augment drug repurposing with the identification of appropriate molecular targets,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfab877120e7d550a1ab1e8d401926f1
http://europepmc.org/articles/PMC8520174
http://europepmc.org/articles/PMC8520174
Autor:
Debasmita Saha, G. Naga Rama Devi, Sivakumar Ponnusamy, Jyotsna Pandit, Sushma Jaiswal, Pranjit Kumar Bhuyan
Publikováno v:
2022 IEEE 2nd Mysore Sub Section International Conference (MysuruCon).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18b4b2aa0bb4aa4be04bb5f89d7be3b7
https://doi.org/10.1109/mysurucon55714.2022.9972740
https://doi.org/10.1109/mysurucon55714.2022.9972740
Autor:
Debasmita Saha, Erica Lane Smith, Katie R. Ryan, Baku Acharya, Naga Rajiv Lakkaniga, Brendan Frett, Noemi Garcia Garcia
Publikováno v:
J Med Chem
REarranged during Transfection (RET) is a receptor tyrosine kinase essential for the normal development and maturation of a diverse range of tissues. Aberrant RET signaling in cancers, due to RET mutations, gene fusions, and over-expression, results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d900c6140bc51abc4a51602080b588a3
https://doi.org/10.1021/acs.jmedchem.0c02167
https://doi.org/10.1021/acs.jmedchem.0c02167
Publikováno v:
ChemMedChem
A fragment-based drug discovery approach using a pyrazoloadenine fragment library was utilized to uncover new molecules that target the RET (REarranged during Transfection) oncoprotein, which is a driver oncoprotein in ~2% of non-small cell lung canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f3b737bf1a703978c6ecc177c789508
https://doi.org/10.1002/cmdc.202100013
https://doi.org/10.1002/cmdc.202100013
Autor:
Kennith Swafford, Baku Acharya, Ying-Zhi Xu, Thomas Raney, Mason McCrury, Debasmita Saha, Brendan Frett, Samantha Kendrick
Publikováno v:
Genes; Volume 13; Issue 7; Pages: 1144
The aggressive nature of the activated B cell such as (ABC) subtype of diffuse large B cell (DLBCL) is frequently associated with altered B cell Receptor (BCR) signaling through the activation of key components including the scaffolding protein, CARD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d687ee05240826ca62f314cf85591c5