Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Debashree Basu"'
Autor:
Ryan M. Baxley, Wendy Leung, Megan M. Schmit, Jacob Peter Matson, Lulu Yin, Marissa K. Oram, Liangjun Wang, John Taylor, Jack Hedberg, Colette B. Rogers, Adam J. Harvey, Debashree Basu, Jenny C. Taylor, Alistair T. Pagnamenta, Helene Dreau, Jude Craft, Elizabeth Ormondroyd, Hugh Watkins, Eric A. Hendrickson, Emily M. Mace, Jordan S. Orange, Hideki Aihara, Grant S. Stewart, Edward Blair, Jeanette Gowen Cook, Anja-Katrin Bielinsky
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Minichromosome maintenance protein 10 (MCM10) is critical for eukaryotic DNA replication. Here, by modelling MCM10 variants in human cell lines, the authors reveal a mechanism of MCM10-associated disease, finding that loss of MCM10 function constrain
Externí odkaz:
https://doaj.org/article/fcda6dd35e9949f888622bfe0a813011
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e12489 (2010)
BACKGROUND: HU a small, basic, histone like protein is a major component of the bacterial nucleoid. E. coli has two subunits of HU coded by hupA and hupB genes whereas Mycobacterium tuberculosis (Mtb) has only one subunit of HU coded by ORF Rv2986c (
Externí odkaz:
https://doaj.org/article/e65ca4adca9c4795b096941cc587b8ce
Publikováno v:
The Journal of Biological Chemistry
In a previous study we showed that replication through the N1-methyl-deoxyadenosine (1-MeA) adduct in human cells is mediated via three different Polι/Polθ, Polη, and Polζ dependent pathways. Based on biochemical studies with these Pols, in the P
Autor:
Adam J. Harvey, Lulu Yin, Jacob Peter Matson, Jack Hedberg, Debashree Basu, John Taylor, Megan Schmit, Liangjun Wang, Jenny C. Taylor, Elizabeth Ormondroyd, Jordan S. Orange, Hideki Aihara, Edward Blair, Colette B. Rogers, Eric A. Hendrickson, Jeanette Gowen Cook, Ryan M. Baxley, Emily M. Mace, Alistair T. Pagnamenta, Anja Katrin Bielinsky, Wendy Leung, Hugh Watkins, Helene Dreau, Jude Craft, Marissa K. Oram, Grant S. Stewart
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Minichromosome maintenance protein 10 (MCM10) is essential for eukaryotic DNA replication. Here, we describe compound heterozygous MCM10 variants in patients with distinctive, but overlapping, clinical phenotypes: natural killer (NK) cell deficiency
Autor:
Elizabeth Ormondroyd, Hideki Aihara, Emily M. Mace, Anja Katrin Bielinsky, James Taylor, Judith Craft, Alistair T. Pagnamenta, Ryan M. Baxley, Ed Blair, Helene Dreau, Jacob Peter Matson, Wendy Leung, Debashree Basu, Jenny C. Taylor, Grant S. Stewart, Megan Schmit, Jack Hedberg, Hugh Watkins, Adam J. Harvey, Lynn Wang, Colette B. Rogers, Eric A. Hendrickson, Lulu Yin, Cook Jg, Marissa K. Oram, Jordan S. Orange
Minichromosome maintenance protein 10 (Mcm10) is essential for eukaryotic DNA replication. Here, we describe compound heterozygous MCM10 mutations in patients with distinctive but overlapping clinical phenotypes – natural killer (NK) cell deficienc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7c950e29951ab73bbca61c278674d00
https://doi.org/10.1101/844498
https://doi.org/10.1101/844498
Autor:
Satya Prakash, Karthi Sellamuthu, Debashree Basu, Robert E. Johnson, Jung-Hoon Yoon, Louise Prakash
Publikováno v:
Life Science Alliance
As an integral scaffolding component of DNA polymerase (Pol) zeta, Pol lambda adapts Pol zeta–dependent translesion synthesis to operate in a predominantly error-free manner in human cells.
By extending synthesis opposite from a diverse array
By extending synthesis opposite from a diverse array
Autor:
Jung Hoon Yoon, Louise Prakash, Jeseong Park, Satya Prakash, Mark J. McArthur, Maki Wakamiya, Debashree Basu
Publikováno v:
Cell. 176:1295-1309.e15
Summary Cancers from sun-exposed skin accumulate “driver” mutations, causally implicated in oncogenesis. Because errors incorporated during translesion synthesis (TLS) opposite UV lesions would generate these mutations, TLS mechanisms are presume
Autor:
Afshin Mashadi-Hossein, Julie Rytlewski, MD Shamsuzzaman, Debashree Basudhar, Mandeep Takhar, Ana Kostic, Timothy B. Campbell, Salomon Manier, Yi Lin, Nathan Martin
Publikováno v:
HemaSphere, Vol 7, p e1004207 (2023)
Externí odkaz:
https://doaj.org/article/4101eb2002f1467cbcd77f260b2fb62e
Autor:
Melissa Alsina, Madhav Dhodapkar, Jesus Berdeja, Krina Patel, Shambavi Richard, Ravi Vij, Xavier Leleu, Daniel Egan, P. Leif Bergsagel, Reshef Ran, Saad Z Usmani, Anna Truppel-Hartmann, Debashree Basudhar, Ethan Thompson, Xirong Zheng, Xiaobo Zhong, Chiara Greggio, Mihaela Popa Mckiver, Marlene Carrasco Alfonso, David Siegel
Publikováno v:
HemaSphere, Vol 7, p e90596a3 (2023)
Externí odkaz:
https://doaj.org/article/6236526bdbd74b7b92eb7a5ad306efce
Autor:
Debashree Basu, Sanjeev Khosla, Shekhar C. Mande, Garima Khare, Anil K. Tyagi, Shashi Bala Singh
Publikováno v:
Nucleic Acids Research
The Mycobacterium tuberculosis genome sequence reveals remarkable absence of many nucleoid-associated proteins (NAPs), such as HNS, Hfq or DPS. In order to characterize the nucleoids of M. tuberculosis, we have attempted to identify NAPs, and report