Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Debashish U Menon"'
Publikováno v:
eLife, Vol 12 (2024)
We present evidence implicating the BAF (BRG1/BRM Associated Factor) chromatin remodeler in meiotic sex chromosome inactivation (MSCI). By immunofluorescence (IF), the putative BAF DNA binding subunit, ARID1A (AT-rich Interaction Domain 1 a), appeare
Externí odkaz:
https://doaj.org/article/ecae72b709cd4b5d9fa93fdc7fa031db
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 12, Iss 6 (2022)
AbstractRBBP4 is a subunit of the chromatin remodeling complexes known as Polycomb repressive complex 2 and histone deacetylase 1/2-containing complexes. These complexes are responsible for histone H3 lysine 27 methylation and deacetylation, respecti
Externí odkaz:
https://doaj.org/article/7a61712067e6401693d2b9778cf11eb2
Publikováno v:
bioRxiv
We present evidence implicating the BAF (BRG1/BRM Associated Factor) chromatin remodeler in meiotic sex chromosome inactivation (MSCI). By immunofluorescence (IF), the putative BAF DNA binding subunit, ARID1A (AT-rich Interaction Domain 1a), appeared
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9776db969ba32570d0a34aa3c196e48
https://doi.org/10.1101/2023.05.25.542290
https://doi.org/10.1101/2023.05.25.542290
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
The mammalian SWI/SNF nucleosome remodeler is essential for spermatogenesis. Here, we identify a role for ARID2, a PBAF (Polybromo - Brg1 Associated Factor)-specific subunit, in meiotic division. Arid2cKO spermatocytes arrest at metaphase-I and are d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d310d9936aa902858704abc5503b4f4c
http://europepmc.org/articles/PMC8589837
http://europepmc.org/articles/PMC8589837
RBBP4 is a core subunit of polycomb repressive complex 2 (PRC2) and HDAC1/2-containing complexes, which are responsible for histone H3 lysine 27 (H3K27) methylation and deacetylation respectively. However, the mechanisms by which RBBP4 modulates the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::932ad7932a77a066ffff9086507420ab
https://doi.org/10.1101/2021.09.09.459568
https://doi.org/10.1101/2021.09.09.459568
Autor:
Terry Magnuson, Debashish U. Menon
BRG1, a catalytic subunit of the mammalian SWI/SNF nucleosome remodeler is essential for male meiosis1. In addition to BRG1, multiple subunits (~10-14) some of which are mutually exclusive, constitute biochemically distinct SWI/SNF subcomplexes, whos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1569e3ac8b8a5b0e6780d744c485277b
Autor:
Debashish U. Menon, Daniel C. Tarquinio, Benjamin D. Philpot, Steven J. Gray, David M. Katz, Monica Coenraads, Adrian Bird
Publikováno v:
Trends in Neurosciences. 39:100-113
Lying at the intersection between neurobiology and epigenetics, Rett syndrome (RTT) has garnered intense interest in recent years, not only from a broad range of academic scientists, but also from the pharmaceutical and biotechnology industries. In a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dca3f2574d37cabcf7ceb68f9f129d33
https://doi.org/10.1016/j.tins.2015.12.008
https://doi.org/10.1016/j.tins.2015.12.008
Publikováno v:
Development
A deficiency in BRG1, the catalytic subunit of the SWI/SNF chromatin remodeling complex, results in a meiotic arrest during spermatogenesis. Here, we explore the causative mechanisms. BRG1 is preferentially enriched at active promoters of genes essen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b8542333b6aeff97cc25f4bceae282c
https://doi.org/10.1101/476143
https://doi.org/10.1101/476143
Autor:
Barbara P. Rattner, Richard L. Kelley, Victoria H. Meller, Victoria A. Moran, Kathryn Hughes Barry, Manasi S. Apte, Rachel M. Zunder, Debashish U. Menon
Publikováno v:
G3: Genes|Genomes|Genetics
Methods for altering the sequence of endogenous Drosophila melanogaster genes remain labor-intensive. We have tested a relatively simple strategy that enables the introduction of engineered mutations in the vicinity of existing P-elements. This metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b58286fc59eddd24d2d32646ba796e48
https://doi.org/10.1534/g3.113.008508
https://doi.org/10.1534/g3.113.008508
Publikováno v:
Biology of Reproduction. 94
The ability to faithfully transmit genetic information across generations via the germ cells is a critical aspect of mammalian reproduction. The process of germ cell development requires a number of large-scale modulations of chromatin within the nuc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b255baafd297042c47e431180d7ab862
https://doi.org/10.1095/biolreprod.115.135533
https://doi.org/10.1095/biolreprod.115.135533