Convergent synthesis of a tetrasaccharide repeating unit of the O-specific polysaccharide from the cell wall lipopolysaccharide of Azospirillum brasilense strain Sp7

Autor: Pintu Kumar Mandal, Debashis Dhara, Anup Kumar Misra

Publikováno v: Beilstein Journal of Organic Chemistry, Vol 10, Iss 1, Pp 293-299 (2014)

A straightforward convergent synthesis has been carried out for the tetrasaccharide repeating unit of the O-specific cell wall lipopolysaccharide of the strain Sp7 of Azospirillum brasilense. The target tetrasaccharide has been synthesized from suita

Externí odkaz: https://doaj.org/article/859c239d460645999aafbda29361f371

Exploratory N‐Protecting Group Manipulation for the Total Synthesis of Zwitterionic Shigella sonnei Oligosaccharides

Autor: Laurence A. Mulard, Debashis Dhara

Publikováno v: Chemistry-A European Journal
Chemistry-A European Journal, 2021, 27 (18), pp.5694-5711. ⟨10.1002/chem.202003480⟩
Chemistry (Weinheim an Der Bergstrasse, Germany)

Shigella sonnei surface polysaccharides are well‐established protective antigens against this major cause of diarrhoeal disease. They also qualify as unique zwitterionic polysaccharides (ZPSs) featuring a disaccharide repeating unit made of two 1,2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e7c17bfe2067d7a02443ad8ffe78a56
https://doi.org/10.1002/chem.202003480

Syntheses of Salmonella Paratyphi A Associated Oligosaccharide Antigens and Development towards Anti‐Paratyphoid Fever Vaccines

Autor: Khandra T. Sears, Scott M Baliban, Zahra Rashidijahanabad, Xuefei Huang, Chang-Xin Huo, Anup Kumar Misra, Sharon M. Tennant, Setare Tahmasebi Nick, Debashis Dhara

Publikováno v: Chemistry

With the emergence of multidrug resistant Salmonella strains, the development of anti-Salmonella vaccines is an important task. Currently there are no approved vaccines against Salmonella Paratyphi A, the leading cause of paratyphoid fever. To fill t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd69e62247e2f9dd0bd410a05dc741de
https://doi.org/10.1002/chem.202002401

C-Glycosylated cinnamoylfuran derivatives as novel anti-cancer agents

Autor: Debashis Dhara, Kuladip Jana, Pravat Kumar Parida, Anup Kumar Misra, Ravichandran Yesuvadian, Anshupriya Si, Ananya Dutta

Publikováno v: RSC Advances. 7:28853-28864

A series of C-glycosylated cinnamoylfuran derivatives were synthesized in excellent yield from free sugars. The C-glycosylated furan derivatives were prepared under aqueous reaction conditions. The anticancer potentials of the synthesized compounds w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d310237747fff659550746b5f231d3f1
https://doi.org/10.1039/c7ra04207h

C -cinnamoyl glycosides as a new class of anti-filarial agents

Autor: Anup Kumar Misra, Anirban Bhunia, Santi P. Sinha Babu, Rajiv K. Kar, Pravat Kumar Parida, Debashis Dhara, Priya Roy, Kuladip Jana

Publikováno v: European Journal of Medicinal Chemistry. 114:308-317

A series of C-cinnamoyl glycosides has been synthesized in good yield by the BF3·OEt2 catalyzed aldol condensation of C-glycosylated acetone derivative with a variety of aromatic aldehydes. The synthesized compounds were evaluated for their potentia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49813e760c2ed455d9762753a44dd8af
https://doi.org/10.1016/j.ejmech.2016.03.001