Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Debarati, Dasgupta"'
Autor:
Mohd Adnan, Debarati DasGupta, Saleha Anwar, Anas Shamsi, Arif Jamal Siddiqui, Mejdi Snoussi, Fevzi Bardakci, Mitesh Patel, Md Imtaiyaz Hassan
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Hyperphosphorylation of tau is an important event in Alzheimer’s disease (AD) pathogenesis, leading to the generation of “neurofibrillary tangles,” a histopathological hallmark associated with the onset of AD and related tauopathi
Externí odkaz:
https://doaj.org/article/54ed545a847a4c39b66473cfef771977
Autor:
Swapnil Wagle, Richard D. Smith, Anthony J. Dominic, Debarati DasGupta, Sunil Kumar Tripathi, Heather A. Carlson
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Binding MOAD is a database of protein–ligand complexes and their affinities with many structured relationships across the dataset. The project has been in development for over 20 years, but now, the time has come to bring it to a close. Cu
Externí odkaz:
https://doaj.org/article/ff981105e2c744438da551d3ab4d0764
Autor:
Ghulam Md. Ashraf, Debarati DasGupta, Mohammad Zubair Alam, Saleh S. Baeesa, Badrah S. Alghamdi, Firoz Anwar, Thamer M. A. Alqurashi, Sharaf E. Sharaf, Waleed Al Abdulmonem, Mohammed A. Alyousef, Fahad A. Alhumaydhi, Anas Shamsi
Publikováno v:
Molecules, Vol 28, Iss 2, p 600 (2023)
The updated affiliation information can be seen in the affiliation part of this correction [...]
Externí odkaz:
https://doaj.org/article/0c074cdc80a04107b53f684144ceb0b2
Autor:
Ghulam Md. Ashraf, Debarati DasGupta, Mohammad Zubair Alam, Saleh S. Baeesa, Badrah S. Alghamdi, Firoz Anwar, Thamer M. A. Alqurashi, Sharaf E. Sharaf, Waleed Al Abdulmonem, Mohammed A. Alyousef, Fahad A. Alhumaydhi, Anas Shamsi
Publikováno v:
Molecules, Vol 27, Iss 14, p 4652 (2022)
Microtubule affinity regulating kinase 4 (MARK4) regulates the mechanism of microtubules by its ability to phosphorylate the microtubule-associated proteins (MAP’s). MARK4 is known for its major role in tau phosphorylation via phosphorylating Ser26
Externí odkaz:
https://doaj.org/article/6fe376e7026c46a88a77b7132238cd44
Autor:
Mohd Adnan, Saleha Anwar, Debarati DasGupta, Mitesh Patel, Abdelbaset Mohamed Elasbali, Hassan H. Alhassan, Alaa Shafie, Arif Jamal Siddiqui, Fevzi Bardakci, Mejdi Snoussi, Md. Imtaiyaz Hassan
Publikováno v:
International Journal of Biological Macromolecules. 224:188-195
Microtubule-affinity regulating kinase 4 (MARK4) is linked with the development of cancer, diabetes and neurodegenerative diseases. Due to its direct role in the hyperphosphorylation of tau protein, MARK4 is considered as an attractive target to figh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a3b85e4e69292fd06564bafd8ac73bb
https://doi.org/10.1016/j.ijbiomac.2022.10.115
https://doi.org/10.1016/j.ijbiomac.2022.10.115
Autor:
Bin Xue, Debarati DasGupta, Manzar Alam, Mohd Shahnawaz Khan, Shuo Wang, Anas Shamsi, Asimul Islam, Md. Imtaiyaz Hassan
Publikováno v:
Journal of Cellular Biochemistry. 123:1381-1393
Iron deposition in the central nervous system (CNS) is one of the causes of neurodegenerative diseases. Human transferrin (hTf) acts as an iron carrier present in the blood plasma, preventing it from contributing to redox reactions. Plant compounds a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3ddcd87629efa534c6655a5fa6c87bf
https://doi.org/10.1002/jcb.30299
https://doi.org/10.1002/jcb.30299
Publikováno v:
ACS Applied Bio Materials.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d409848752da943907bf3dad3db46b2b
https://doi.org/10.1021/acsabm.2c01079
https://doi.org/10.1021/acsabm.2c01079
Autor:
Taraprasad Das, Vivek Pravin Dave, Alok Sen, Priyanka A. Mahendrakar, Sanchita Mitra, Anthony Vipin Das, Prajna Lalitha, Joveeta Joseph, Ashik Mohamed, Pillutla L. Nimeshika, Gumpalli S. Prashanthi, Alankrita Muralidhar, Umesh Chandra Behera, Prithviraj Uday, Rameshkumar Gunasekaran, Muna Bhende, Debarati Dasgupta, Savitri Sharma, Sucheta Kulkarni, Jaishree Gandhi, Appakkudal R. Anand, Manisha Agarwal
Publikováno v:
Ophthalmology Retina. 6:243-251
Purpose To evaluate the clinical and microbiological features of a large cohort of culture-confirmed fungal endophthalmitis across India. Design Cross-sectional hospital-based retrospective medical records review. Participants Seven large tertiary ey
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35b0726ecc75c2774aaea599d503de73
https://doi.org/10.1016/j.oret.2021.09.006
https://doi.org/10.1016/j.oret.2021.09.006
Publikováno v:
J Chem Inf Model
In this study, we target the main protease (M(pro)) of the SARS-CoV-2 virus as it is a crucial enzyme for viral replication. Herein, we report three plausible allosteric sites on M(pro) that can expand structure-based drug discovery efforts for new M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::607f6176275397b1bee62d95218571a4
https://doi.org/10.1021/acs.jcim.1c01223
https://doi.org/10.1021/acs.jcim.1c01223
Publikováno v:
J Comput Chem
Regulator of G protein signaling 4 (RGS4) is an intracellular protein that binds to the Gα subunit ofheterotrimeric G proteins and aids in terminating G protein coupled receptor signaling. RGS4 has been implicated in pain, schizophrenia, and the con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50c13bb6fe4f0af50e93b7bcb36fafd2
https://doi.org/10.1002/jcc.26747
https://doi.org/10.1002/jcc.26747