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pro vyhledávání: '"Debapratim Dutta"'
Autor:
Debapratim Dutta, Joseph E. Wedekind
Publikováno v:
Journal of Biological Chemistry. 295:2555-2567
Riboswitches are a class of nonprotein-coding RNAs that directly sense cellular metabolites to regulate gene expression. They are model systems for analyzing RNA-ligand interactions and are established targets for antibacterial agents. Many studies h
Autor:
Jermaine L. Jenkins, Debapratim Dutta, Cameron D. Baker, Joseph E. Wedekind, Chapin E. Cavender, Griffin M. Schroeder, David H. Mathews, John M. Ashton, Elizabeth M Pritchett
Publikováno v:
Nucleic Acids Research
Riboswitches are structured RNA motifs that recognize metabolites to alter the conformations of downstream sequences, leading to gene regulation. To investigate this molecular framework, we determined crystal structures of a preQ1-I riboswitch in eff
Autor:
Debapratim, Dutta, Joseph E, Wedekind
Publikováno v:
The Journal of biological chemistry. 295(9)
Riboswitches are a class of nonprotein-coding RNAs that directly sense cellular metabolites to regulate gene expression. They are model systems for analyzing RNA-ligand interactions and are established targets for antibacterial agents. Many studies h
Autor:
Debapratim Dutta, David H. Mathews, Aleksandar Spasic, Leslie A. Salas-Estrada, Alan Grossfield, Louis G. Smith, Zhen Tan
This study describes a comparison between melts and simulated stabilities of the same RNAs that could be used to benchmark RNA force fields, and potentially to determine future melt-ing experiments. Using umbrella sampling molecular simulations of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb4e3fd40b9165745669204a46ef10ab
https://europepmc.org/articles/PMC6533901/
https://europepmc.org/articles/PMC6533901/
Noncoding RNAs engage in numerous biological activities including gene regulation. To fully understand RNA function it is necessary to probe biologically relevant conformations in living cells. To address this challenge, we coupled RNA-mediated regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cbb8c93302f02d4dd1be94f7e00d7e1
https://europepmc.org/articles/PMC6643267/
https://europepmc.org/articles/PMC6643267/
Publikováno v:
The Journal of biological chemistry. 292(23)
Divalent ions fulfill essential cellular roles and are required for virulence by certain bacteria. Free intracellular Mg2+ can approach 5 mm, but at this level Mn2+, Ni2+, or Co2+ can be growth-inhibitory, and magnesium fluoride is toxic. To maintain
Autor:
Jospeh E. Wedekind, Debapratim Dutta, David H. Mathews, Chapin E. Cavender, Jermaine L. Jenkins, Andrew M. DiCola, Griffin M. Schroeder
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 75:a18-a18
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 74:a204-a204