Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Debao Xie"'
Dosage suppressors of gpn2ts mutants and functional insights into the role of Gpn2 in budding yeast.
Publikováno v:
PLoS ONE, Vol 19, Iss 12, p e0313597 (2024)
Gpn2 is a highly conserved protein essential for the assembly of RNA polymerase II (RNAPII) in eukaryotic cells. Mutations in Gpn2, specifically Phe105Tyr and Leu164Pro, confer temperature sensitivity and significantly impair RNAPII assembly. Despite
Externí odkaz:
https://doaj.org/article/c55f0ace364e4a8f92816712fbafed30
Publikováno v:
Biotechnology & Biotechnological Equipment, Vol 34, Iss 1, Pp 287-293 (2020)
The objective of this study was isolation of humanized single-chain variable fragment (scFv) antibodies against IL1RAP, a promising cancer marker in leukemia and other tumors. Here, we screened for antibody fragments that recognized IL1RAP using a ph
Externí odkaz:
https://doaj.org/article/136a664eabf9434a8c3b760c494cb264
Autor:
Pan Li, Xueqin Liu, Zhimin Hao, Yanrong Jia, Xiangdong Zhao, Debao Xie, Jingao Dong, Fanli Zeng
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Cip1, a newly identified yeast analog of p21, is a Cln3-CDK inhibitor that negatively regulates cell-cycle START. However, its function remains poorly understood. In this study, we found that deletion of CLN3 did not result in bypass of G1-phase arre
Externí odkaz:
https://doaj.org/article/01d03050e4564ca69dac003e72d468f6
Autor:
Lujie Ma, Le Wang, Mengdi Gao, Xinjie Zhang, Xiangdong Zhao, Debao Xie, Jing Zhang, Zhen Wang, Lifeng Hou, Fanli Zeng
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 36(11)
RNA polymerase II (RNAPII) is an essential machinery for catalyzing mRNA synthesis and controlling cell fate in eukaryotes. Although the structure and function of RNAPII have been relatively defined, the molecular mechanism of its assembly process is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06c942ac93461401049fe58b33d1eaff
https://pubmed.ncbi.nlm.nih.gov/36190433
https://pubmed.ncbi.nlm.nih.gov/36190433
Publikováno v:
The FASEB Journal. 34:15547-15558
RNA polymerase II is one of the most vital macromolecular complexes in eukaryotes and the assembly of such complete enzyme requires many factors. Three members of GPN-loop GTPase family Npa3/Gpn1, Gpn2, and Gpn3 participate in the biogenesis of RNA p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::274a7a46eaf50ef2fd33a2dbc9278c8f
https://doi.org/10.1096/fj.202001523r
https://doi.org/10.1096/fj.202001523r
Publikováno v:
Biotechnology & Biotechnological Equipment, Vol 34, Iss 1, Pp 287-293 (2020)
The objective of this study was isolation of humanized single-chain variable fragment (scFv) antibodies against IL1RAP, a promising cancer marker in leukemia and other tumors. Here, we screened for antibody fragments that recognized IL1RAP using a ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ab8745a2c429980b3c6cd5603dd4c47
Publikováno v:
Biotechnology letters. 41(8-9)
Establish a method to restrict unexpected fragments including stop codons in scFv library and generate a thermo resistant strain for screening of thermal stable scFv sequences. Here, we have constructed a T2A–Leu2 system for selection of yeast surf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53e446c3837eb192d74a4ffe2812cda9
https://pubmed.ncbi.nlm.nih.gov/31300936
https://pubmed.ncbi.nlm.nih.gov/31300936