Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Debamita Paul"'
Ethenoguanines undergo glycosylation by nucleoside 2'-deoxyribosyltransferases at non-natural sites.
Autor:
Wenjie Ye, Debamita Paul, Lina Gao, Jolita Seckute, Ramiah Sangaiah, Karupiah Jayaraj, Zhenfa Zhang, P Alexandre Kaminski, Steven E Ealick, Avram Gold, Louise M Ball
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115082 (2014)
Deoxyribosyl transferases and functionally related purine nucleoside phosphorylases are used extensively for synthesis of non-natural deoxynucleosides as pharmaceuticals or standards for characterizing and quantitating DNA adducts. Hence exploring th
Externí odkaz:
https://doaj.org/article/1f8e2d50ab4d4487abe619e7dcb3e613
Autor:
Jung Hyun Min, Anjum Ansari, Jagannath Kuchlyan, Suse Broyde, Saroj Baral, Amirrasoul Tavakoli, Debamita Paul, Hong Mu
Publikováno v:
RSC Chemical Biology
Biomolecular structural changes upon binding/unbinding are key to their functions. However, characterization of such dynamical processes is difficult as it requires ways to rapidly and specifically trigger the assembly/disassembly as well as ways to
Autor:
Suse Broyde, Debamita Paul, Sagnik Chakraborty, Qing Dai, Xuejing Chen, Amirrasoul Tavakoli, Hong Mu, Jung Hyun Min, Anjum Ansari, Chuan He
Publikováno v:
Nucleic Acids Research
XPC/Rad4 initiates eukaryotic nucleotide excision repair on structurally diverse helix-destabilizing/distorting DNA lesions by selectively ‘opening’ these sites while rapidly diffusing along undamaged DNA. Previous structural studies showed that
Autor:
Jung Hyun Min, Ouathek Ouerfelli, Debamita Paul, Hong Zhao, Suse Broyde, Philip D. Jeffrey, Hong Mu
Publikováno v:
Nucleic Acids Research
Failure in repairing ultraviolet radiation-induced DNA damage can lead to mutations and cancer. Among UV-lesions, the pyrimidine–pyrimidone (6-4) photoproduct (6-4PP) is removed from the genome much faster than the cyclobutane pyrimidine dimer (CPD
Impact of DNA sequences in the DNA duplex opening by the Rad4/XPC nucleotide excision repair complex
Rad4/XPC is a key DNA damage sensor for nucleotide excision repair (NER) in eukaryotes. Rad4/XPC recognizes diverse bulky lesions by flipping out two lesion-containing nucleotide pairs and inserting a β-hairpin from the BHD3 domain (β-hairpin3) int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36e11a66eb67f014fac5f2e16cf7fe3b
https://doi.org/10.1101/2020.01.16.909549
https://doi.org/10.1101/2020.01.16.909549
Autor:
Jung Hyun Min, Amirrasoul Tavakoli, Sagnik Chakraborty, Debamita Paul, Qing Dai, Chuan He, Hong Mu, Anjum Ansari, Suse Broyde
Publikováno v:
DNA Repair (Amst)
Rad4/XPC recognizes diverse DNA lesions to initiate nucleotide excision repair (NER). However, NER propensities among lesions vary widely and repair-resistant lesions are persistent and thus highly mutagenic. Rad4 recognizes repair-proficient lesions
Autor:
Suse Broyde, Hong Mu, Sagnik Chakraborty, Debamita Paul, Jung Hyun Min, Peter J. Steinbach, Anjum Ansari
Publikováno v:
Nucleic Acids Research
Rad4/XPC recognizes diverse DNA lesions including ultraviolet-photolesions and carcinogen-DNA adducts, initiating nucleotide excision repair. Studies have suggested that Rad4/XPC senses lesion-induced helix-destabilization to flip out nucleotides fro
Publikováno v:
Biophysical Journal. 120:9a
Autor:
Jung Hyun Min, Debamita Paul, Sagnik Chakraborty, Saroj Baral, Phoebe A. Rice, Anjum Ansari, Peter J. Steinbach
Publikováno v:
Biophysical Journal. 116:499a
Autor:
Geraldine Harriman, Ruiying Wang, William F. Westlin, Rosana Kapeller, Sathesh Bhat, Asish K. Saha, Xinyi Huang, Liang Tong, Debamita Paul, Jeremy R. Greenwood, H. James Harwood
Publikováno v:
Proceedings of the National Academy of Sciences. 113
Simultaneous inhibition of the acetyl-CoA carboxylase (ACC) isozymes ACC1 and ACC2 results in concomitant inhibition of fatty acid synthesis and stimulation of fatty acid oxidation and may favorably affect the morbidity and mortality associated with