Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Debaleena Basu"'
Autor:
Christopher Fotsch, Debaleena Basu, Ryan Case, Qing Chen, Pratibha C. Koneru, Mei-Chu Lo, Rachel Ngo, Pooja Sharma, Amit Vaish, Xiang Yi, Stephan G. Zech, Peter Hodder
Publikováno v:
SLAS Discovery, Vol 29, Iss 4, Pp 100159- (2024)
To confirm target engagement of hits from our high-throughput screening efforts, we ran biophysical assays on several hundreds of hits from 15 different high-throughput screening campaigns. Analyzing the biophysical assay results from these screening
Externí odkaz:
https://doaj.org/article/2deb87592cfb4d24ab3ef0bdbdb9d00b
Autor:
Debaleena Basu, Nilgun E. Tumer
Publikováno v:
Toxins, Vol 7, Iss 5, Pp 1467-1485 (2015)
Shiga toxin producing Escherichia coli O157:H7 (STEC) is one of the leading causes of food-poisoning around the world. Some STEC strains produce Shiga toxin 1 (Stx1) and/or Shiga toxin 2 (Stx2) or variants of either toxin, which are critical for the
Externí odkaz:
https://doaj.org/article/b6814c7cda2d4543a3fbdfcddd3be749
Trichothecene Mycotoxins Inhibit Mitochondrial Translation—Implication for the Mechanism of Toxicity
Publikováno v:
Toxins, Vol 3, Iss 12, Pp 1484-1501 (2011)
Fusarium head blight (FHB) reduces crop yield and results in contamination of grains with trichothecene mycotoxins. We previously showed that mitochondria play a critical role in the toxicity of a type B trichothecene. Here, we investigated the direc
Externí odkaz:
https://doaj.org/article/3091cd1310e043739e0de622e9dcb20b
Monitoring sequential information is an essential component of our daily lives. Many of these sequences are abstract, in that they do not depend on the individual stimuli, but do depend on an ordered set of rules (e.g., chop then stir when cooking).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ca20f0b71553c740d42d9bdc42b2002
https://doi.org/10.1101/2022.09.19.508576
https://doi.org/10.1101/2022.09.19.508576
Publikováno v:
Journal of Neurophysiology. 126:451-463
A hallmark of intelligent behavior is that we can separate intention from action. To understand the mechanism that gates the flow of information between motor planning and execution, we compared the activity of frontal eye field neurons with motor un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd091c409fb04d8c295acc6b4091e997
https://doi.org/10.1152/jn.00141.2021
https://doi.org/10.1152/jn.00141.2021
Autor:
Debaleena Basu, Aditya Murthy
Publikováno v:
Journal of Neurophysiology. 123:107-119
We use sequences of saccadic eye movements to continually explore our visual environments. Previous behavioral studies have established that saccades in a sequence may be programmed in parallel by the oculomotor system. In this study, we tested the n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1668b3adf85b1edbebda202878eb35de
https://doi.org/10.1152/jn.00545.2018
https://doi.org/10.1152/jn.00545.2018
SummaryGoal-directed behavior involves the transformation of neural movement plans into appropriate muscle activity patterns. Studies involving single saccades have shown that a rapid, direct pathway links saccade planning in frontal eye fields (FEF)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd04b79238c6df8e087076bad172edca
https://doi.org/10.1101/2021.08.31.458347
https://doi.org/10.1101/2021.08.31.458347
A hallmark of intelligent behavior is that we can separate intention from action. To understand the mechanism that gates the flow of information between motor planning and execution, we compared the activity of frontal eye field neurons with motor un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35559a65f479336aaa0896d9842ed1a4
https://doi.org/10.1101/2021.02.01.429125
https://doi.org/10.1101/2021.02.01.429125
Publikováno v:
Proc Natl Acad Sci U S A
SummarySequences of saccadic eye movements are instrumental in navigating our visual environment. While neural activity has been shown to ramp up to a threshold before single saccades, the neural underpinnings of multiple saccades is unknown. To unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d17cefe273d9bb571396b5a33dcb5fc2
https://doi.org/10.1101/2020.12.04.411454
https://doi.org/10.1101/2020.12.04.411454