Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Debabrata Dey"'
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105088- (2022)
Summary: Crowded environments are known to affect the diffusion of macromolecules, but their effects on the diffusion of small molecules are largely uncharacterized. We investigate how three protein crowders, bovine serum albumin (BSA), hen egg-white
Externí odkaz:
https://doaj.org/article/383cf24fed8443039b9241f39ee1fc0d
Autor:
Debabrata Dey, Shir Marciano, Anna Poryvai, Ondřej Groborz, Lucie Wohlrábová, Tomás Slanina, Gideon Schreiber
Drug efficacy depends not only on delivery but also on intracellular diffusion, distribution and availability. Yet, more than a half of pharmaceutical drugs are weakly basic and thus, protonated and sequestered at intracellular pH. Protonation reduce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f368b1e01da5e32e9fd320af212571ea
https://doi.org/10.1101/2023.04.19.537456
https://doi.org/10.1101/2023.04.19.537456
Publikováno v:
Management Science. 68:2914-2931
The role of education and enforcement in ensuring compliance with a law or policy has been debated for more than a century now. We reopen this debate in the context of security circumvention by employees, currently a leading cause of information secu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95f3388db607c00a3c3124b824ee09ac
https://doi.org/10.1287/mnsc.2021.4027
https://doi.org/10.1287/mnsc.2021.4027
Autor:
Chloé I. Charendoff, Agathe Subtil, Shir Marciano, Debabrata Dey, Jiří Zahradník, Gideon Schreiber, Lucie Kolářová
Publikováno v:
ACS Synthetic Biology
ACS Synthetic Biology, 2021, 10 (12), pp.3445-3460. ⟨10.1021/acssynbio.1c00395⟩
ACS Synthetic Biology, 2021, 10 (12), pp.3445-3460. ⟨10.1021/acssynbio.1c00395⟩
International audience; Here, we enhanced the popular yeast display method by multiple rounds of DNA and protein engineering. We introduced surface exposure-tailored reporters, eUnaG2 and DnbALFA, creating a new platform of C and N terminal fusion ve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f288348b44fd2678fc649ac0664b448f
https://doi.org/10.1021/acssynbio.1c00395
https://doi.org/10.1021/acssynbio.1c00395
Publikováno v:
Information Systems Research. 32:653-669
This research develops a micro-economic model to study the impact of support forums on the software industry. Motivated by the rapid growth of forums such as Stack Exchange, Quora, and Yahoo! Answers, we examine what impact they could have on a softw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a88329f8cfead72ae4b582b5d0c4dfa1
https://doi.org/10.1287/isre.2020.0988
https://doi.org/10.1287/isre.2020.0988
Autor:
Shir Marciano, Debabrata Dey, Dina Listov, Sarel J Fleishman, Adar Sonn-Segev, Haydyn Mertens, Florian Busch, Yongseok Kim, Sophie R. Harvey, Vicki H. Wysocki, Gideon Schreiber
Publikováno v:
Chemical science 13(39), 11680-11695 (2022). doi:10.1039/D2SC02794A
Chemical science 13(39), 11680 - 11695 (2022). doi:10.1039/D2SC02794A
Over half the proteins in the E. coli cytoplasm form homo or hetero-oligomeric structures. Experimentally determined structures are often considered in determining a protein's
Over half the proteins in the E. coli cytoplasm form homo or hetero-oligomeric structures. Experimentally determined structures are often considered in determining a protein's
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1da508fd45988fad2d3822ffedf314ed
https://pubmed.ncbi.nlm.nih.gov/36320402
https://pubmed.ncbi.nlm.nih.gov/36320402
Crowded environments are known to affect the diffusion of macromolecules but their effects on the diffusion of small molecules, such as drugs, are largely uncharacterized. Here, we investigate how three macromolecular protein crowders, bovine serum a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90e8fedcb4e71895a41e148675c0ee88
https://doi.org/10.1101/2021.12.30.474528
https://doi.org/10.1101/2021.12.30.474528
Publikováno v:
Management Science. 65:1173-1190
Controlling digital piracy has remained a top priority for manufacturers of information goods, as well as for many governments around the world. Among the many forms taken by digital piracy, we focus on an increasingly common one—namely, online pir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fc350d5d3f8f6c2fb59be54486c9042
https://doi.org/10.1287/mnsc.2017.2984
https://doi.org/10.1287/mnsc.2017.2984
Autor:
Ariane Nunes-Alves, Gideon Schreiber, Vladimir Kiss, Rebecca C. Wade, Shir Marciano, Debabrata Dey
Publikováno v:
Journal of molecular biology. 433(9)
The crowded cellular milieu affect molecular diffusion through hard (occluded space) and soft (weak, non-specific) interactions. Multiple methods have been developed to measure diffusion coefficients at physiological protein concentrations within cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2234e40eacf2901efa5f2472d97a5e39
https://pubmed.ncbi.nlm.nih.gov/33647289
https://pubmed.ncbi.nlm.nih.gov/33647289