Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Deb Ranjan Banerjee"'
Autor:
Aina Bellver-Sanchis, Pedro A Ávila-López, Iva Tic, David Valle-García, Marta Ribalta-Vilella, Luis Labrador, Deb Ranjan Banerjee, Ana Guerrero, Gemma Casadesus, Coralie Poulard, Mercè Pallàs, Christian Griñán-Ferré
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 11, Pp 2532-2542 (2024)
Dysregulation of G9a, a histone-lysine N-methyltransferase, has been observed in Alzheimer’s disease and has been correlated with increased levels of chronic inflammation and oxidative stress. Likewise, microRNAs are involved in many biological pro
Externí odkaz:
https://doaj.org/article/4c3e64e7fae94dd28b961cd5185e547a
Publikováno v:
Journal of Biomolecular Structure and Dynamics. :1-28
Herein, we report a blended ligand and structure-based pharmacophore screening approach to identify new natural leads against the Protein Lysine Methyltransferase 2 (EHMT2/G9a). The EHMT2/G9a has been associated with Cancer, Alzheimer’s, and aging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b026ef3c1b93db300a89f17e97c8411a
https://doi.org/10.1080/07391102.2023.2213346
https://doi.org/10.1080/07391102.2023.2213346
Autor:
Subhabrata Mabhai, Malay Dolai, Surya Kanta Dey, Sujata Maiti Choudhury, Bhriguram Das, Satyajit Dey, Atanu Jana, Deb Ranjan Banerjee
Publikováno v:
New Journal of Chemistry. 46:6885-6898
A naphthalene-based azo armed molecular derivative was synthesized for sensing of Al3+ and cell imaging studies. The fluorescence enhancement is caused by restricted CN isomerization, CHEF on, and PET-off processes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01f46114658ef23cca9964589307c6f4
https://doi.org/10.1039/d1nj05869j
https://doi.org/10.1039/d1nj05869j
The G9a, Lysine Methyltransferase that methylates the histone 3 lysine 9 (H3K9) of the nucleosome, is an excellent epigenetic target having no clinically passed inhibitor currently owing to adverse in vivo ADMET toxicities. In this work, we have carr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45a07c7b746824bda45944e0950f613c
Drug discovery is still behind in the race compared to vaccine discovery in fighting COVID-19. Recently, a few alkaloids from a traditional Indian medicinal plant, Vasaka (Justicia adhatoda), have been linked computationally to the main protease (Mpr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b70e1bc285be05ae4f687f878c33df0
https://doi.org/10.33774/chemrxiv-2021-4bkvh
https://doi.org/10.33774/chemrxiv-2021-4bkvh
Publikováno v:
Journal of the American Chemical Society. 141:14110-14114
Although a functional relationship between active DNA demethylation and chromatin structure is often implied, direct experimental evidence is lacking. We investigated the relationship between chromatin structure and thymine DNA glycosylase (TDG) usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ec6265fbb1ce3851443084bd5110be9
https://doi.org/10.1021/jacs.9b07576
https://doi.org/10.1021/jacs.9b07576
Autor:
Deb Ranjan Banerjee, Charles E. Deckard, James D. Batteas, Wesley W. Wang, Meagan B. Elinski, Meridith L. Buzbee, Jonathan T. Sczepanski
Publikováno v:
Journal of the American Chemical Society. 140:8260-8267
The genomic DNA of eukaryotic cells exists in the form of chromatin, the structure of which controls the biochemical accessibility of the underlying DNA to effector proteins. In order to gain an in depth molecular understanding of how chromatin struc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a89b53bd7729120d67130ae2468424d
https://doi.org/10.1021/jacs.8b04063
https://doi.org/10.1021/jacs.8b04063
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
Despite recent evidence suggesting that histone lysine acetylation contributes to base excision repair (BER) in cells, their exact mechanistic role remains unclear. In order to examine the influence of histone acetylation on the initial steps of BER,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea454e2722ec7610aa9492ff2ffa0d92
https://doi.org/10.1038/s41598-019-52340-0
https://doi.org/10.1038/s41598-019-52340-0
Autor:
Satyajit Dey, Surya Kanta Dey, Malay Dolai, Anamika Dhara, Sujata Maiti Choudhury, Subhabrata Mabhai, Bhriguram Das, Atanu Jana, Deb Ranjan Banerjee
Publikováno v:
Journal of Photochemistry and Photobiology A: Chemistry. 404:112889
The design and synthesis of red light-emitting multianalyte chemosensors have always been a challenging task because of its specific requirement of coordination pocket and selective fluorescence mechanism. Herein, we develop a chemosensor via “thre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e0f72935060101fcb33a0e0437d13d6
https://doi.org/10.1016/j.jphotochem.2020.112889
https://doi.org/10.1016/j.jphotochem.2020.112889
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:1343-1347
Herein we report six novel triazole linked polyphenol-aminobenzene hybrids (3-8) as inhibitors of Mycobacterium tuberculosis FabG4 (Rv0242c), a less explored β-ketoacyl CoA reductase that has immense potential to be the future anti-tuberculosis drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5949e39d74cacf68b10dc1bcbf692fda
https://doi.org/10.1016/j.bmcl.2015.01.014
https://doi.org/10.1016/j.bmcl.2015.01.014