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The Clinical Implications of Death Domain-Associated Protein (DAXX) Expression

Autor: Taek Yong Ko, Jong In Kim, Eok Sung Park, Jeong Min Mun, Sung Dal Park

Publikováno v: Korean Journal of Thoracic and Cardiovascular Surgery, Vol 51, Iss 3, Pp 187-194 (2018)

Background : Death domain-associated protein (DAXX), originally identified as a pro-apoptotic protein, is now understood to be either a pro-apoptotic or an anti-apoptotic factor with a chromatin remodeler, depending on the cell type and context. This

Externí odkaz: https://doaj.org/article/3ba35d192c334fb5b51de0f7b2f87d09

Intrinsically disordered substrates dictate SPOP subnuclear localization and ubiquitination activity

Autor: Amie K. Boal, Scott A. Showalter, Nafiseh Sabri, Roman Rohac, Emery T. Usher, Tanja Mittag

Publikováno v: The Journal of Biological Chemistry

Speckle-type POZ protein (SPOP) is a ubiquitin ligase adaptor that binds substrate proteins and facilitates their proteasomal degradation. Most SPOP substrates present multiple SPOP-binding (SB) motifs and undergo liquid–liquid phase separation wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::865b2261c9773bb5532b2ebeb6469bac
https://pubmed.ncbi.nlm.nih.gov/33894201

Function of the histone variant H3.3 and its chaperone DAXX on heterochromatin organization in pluripotent cells

Autor: Canat, Antoine

Publikováno v: Molecular biology. Université Paris Cité, 2020. English. ⟨NNT : 2020UNIP7245⟩

Most of mammalian genomes are composed of DNA repeated elements. Pericentromeric heterochromatin (PCH) regions are formed of large arrays of major satellite repeats. DNA repeats are often silenced via similar mechanisms such as DNA methylation, H3K9m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1398::16717f6161d92682dca9f7c75c8b8522
https://theses.hal.science/tel-03832812

The Clinical Implications of Death Domain-Associated Protein (DAXX) Expression

Autor: Sung Dal Park, Eok Sung Park, Taek Yong Ko, Jong In Kim, Jeong Min Mun

Publikováno v: Korean Journal of Thoracic and Cardiovascular Surgery, Vol 51, Iss 3, Pp 187-194 (2018)
The Korean Journal of Thoracic and Cardiovascular Surgery

Background : Death domain-associated protein (DAXX), originally identified as a pro-apoptotic protein, is now understood to be either a pro-apoptotic or an anti-apoptotic factor with a chromatin remodeler, depending on the cell type and context. This

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a6e5769f6e0efb02a5e01b1e843fc49
https://doi.org/10.5090/kjtcs.2018.51.3.187