Výsledky vyhledávání - "Dearmond, SJ"

Prion Disease Induces Alzheimer Disease-Like Neuropathologic Changes

Autor: Tousseyn, T, Bajsarowicz, K, Sánchez, H, Gheyara, A, Oehler, A, Geschwind, M, DeArmond, B, DeArmond, SJ

Publikováno v: Journal of neuropathology and experimental neurology, vol 74, iss 9
Tousseyn, T; Bajsarowicz, K; Sánchez, H; Gheyara, A; Oehler, A; Geschwind, M; et al.(2015). Prion Disease Induces Alzheimer Disease-Like Neuropathologic Changes.. Journal of neuropathology and experimental neurology, 74(9), 873-888. doi: 10.1097/NEN.0000000000000228. UCSF: Retrieved from: http://www.escholarship.org/uc/item/6qq7c74r

We examined the brains of 266 patients with prion disease (PrionD) and found that 46 patients (17%) had Alzheimer disease (AD)-like changes. To explore potential mechanistic links between PrionD and AD, we exposed human brain aggregates (BrnAggs) to

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https://escholarship.org/uc/item/6qq7c74r

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Bioluminescence imaging of A beta deposition in bigenic mouse models of Alzheimer's disease (vol 108, pg 2528, 2011)

Autor: Watts, JC, Giles, K, Grillo, SK, Lemus, A, DeArmond, SJ, Prusiner, SB

Publikováno v: Watts, JC; Giles, K; Grillo, SK; Lemus, A; DeArmond, SJ; & Prusiner, SB. (2015). Bioluminescence imaging of A beta deposition in bigenic mouse models of Alzheimer's disease (vol 108, pg 2528, 2011). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 112(9), E1050-E1050. doi: 10.1073/pnas.1502028112. UCSF: Retrieved from: http://www.escholarship.org/uc/item/1wh789j5

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::07dde353ebf9cacf92ae00302a5a6f14
http://www.escholarship.org/uc/item/1wh789j5

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Modulation of Creutzfeldt-Jakob disease prion propagation by the A224V mutation

Autor: Watts, JC, Giles, K, Serban, A, Patel, S, Oehler, A, Bhardwaj, S, Guan, S, Greicius, MD, Miller, BL, Dearmond, SJ, Geschwind, MD, Prusiner, SB

Publikováno v: Watts, JC; Watts, JC; Watts, JC; Giles, K; Giles, K; Serban, A; et al.(2015). Modulation of Creutzfeldt-Jakob disease prion propagation by the A224V mutation. Annals of Neurology. doi: 10.1002/ana.24463. UCSF: Retrieved from: http://www.escholarship.org/uc/item/7f3001jv

© 2015 American Neurological Association. Objective: Mutations in the gene encoding the prion protein (PrP) are responsible for approximately 10 to 15% of cases of prion disease in humans, including Creutzfeldt-Jakob disease (CJD). Here, we report o

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Erratum: Bioluminescence imaging of Aβ deposition in bigenic mouse models of Alzheimer's disease (Proceedings of the National Academy of Sciences of the United States of America (2011) 108 (2528-2533) DOI: 10.1073/pnas. 1019034108)

Autor: Watts, JC, Giles, K, Grillo, SK, Lemus, A, DeArmond, SJ, Prusiner, SB

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, vol 111, iss 10
Watts, JC; Giles, K; Grillo, SK; Lemus, A; DeArmond, SJ; & Prusiner, SB. (2014). Erratum: Bioluminescence imaging of Aβ deposition in bigenic mouse models of Alzheimer's disease (Proceedings of the National Academy of Sciences of the United States of America (2011) 108 (2528-2533) DOI: 10.1073/pnas. 1019034108). Proceedings of the National Academy of Sciences of the United States of America, 111(10), 3895. doi: 10.1073/pnas.1401579111. UCSF: Retrieved from: http://www.escholarship.org/uc/item/2j70k69m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8746361845117334c71b8796e0130e83
https://escholarship.org/uc/item/2j70k69m

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Genetic CJD with a novel E200G mutation in the prion protein gene and comparison with E200K mutation cases

Autor: Kim, MO, Cali, I, Oehler, A, Fong, JC, Wong, K, See, T, Katz, JS, Gambetti, P, Bettcher, BM, Dearmond, SJ

Publikováno v: Kim, MO; Cali, I; Oehler, A; Fong, JC; Wong, K; See, T; et al.(2013). Genetic CJD with a novel E200G mutation in the prion protein gene and comparison with E200K mutation cases. Acta neuropathologica communications, 1(1), 80. doi: 10.1186/2051-5960-1-80. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/3762j150

A novel point mutation resulting in a glutamate-to-glycine substitution in PRNP at codon 200, E200G with codon 129 MV polymorphism (cis valine) and type 2 PrPSc was identified in a patient with a prolonged disease course leading to pathology-proven J

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