Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Dearbhaile O'Donnell"'
Autor:
Roshni D. Kalachand, Ciaran O’Riain, Sinead Toomey, Aoife Carr, Kirsten M. Timms, Sharon O’Toole, Stephen Madden, Mark Bates, John J. O’Leary, Noreen Gleeson, Dearbhaile O’Donnell, Liam Grogan, Oscar Breathnach, Angela Farrelly, Britta Stordal, Bryan T. Hennessy
Publikováno v:
Obstetrics & Gynecology Science, Vol 63, Iss 5, Pp 643-654 (2020)
Objective The therapeutic benefits of poly(ADP-ribose) polymerase inhibitors highlight the need to evaluate BRCA1/2 defects in tubal/ovarian cancer (OC). We sought to determine the pattern and disease characteristics associated with tumor BRCA1/2 mut
Externí odkaz:
https://doaj.org/article/6cbb4fc095ea435da4eec3de790092e5
Autor:
Lauren Brady, Brian Hayes, Gráinne Sheill, Anne-Marie Baird, Emer Guinan, Bryan Stanfill, Tatjana Vlajnic, Orla Casey, Verena Murphy, John Greene, Emma H Allott, Juliette Hussey, Fidelma Cahill, Mieke Van Hemelrijck, Nicola Peat, Lorelei Mucci, Moya Cunningham, Liam Grogan, Thomas Lynch, Rustom P Manecksha, John McCaffrey, Dearbhaile O'Donnell, Orla Sheils, John O'Leary, Sarah Rudman, Ray McDermott, Stephen Finn
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243928 (2020)
BackgroundCirculating tumour cells (CTCs) represent a morphologically distinct subset of cancer cells, which aid the metastatic spread. The ExPeCT trial aimed to examine the effectiveness of a structured exercise programme in modulating levels of CTC
Externí odkaz:
https://doaj.org/article/f01f65e4dcf04888b2513efc808b130d
Autor:
Charles J d'Adhemar, Cathy D Spillane, Michael F Gallagher, Mark Bates, Katie M Costello, Jacqui Barry-O'Crowley, Kathryn Haley, Niamh Kernan, Ciara Murphy, Paul C Smyth, Ken O'Byrne, Stephen Pennington, Aoife A Cooke, Brendan Ffrench, Cara M Martin, Dearbhaile O'Donnell, Bryan Hennessy, Britta Stordal, Stephen Finn, Amanda McCann, Noreen Gleeson, Tom D'Arcy, Brian Flood, Luke A J O'Neill, Orla Sheils, Sharon O'Toole, John J O'Leary
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100816 (2014)
The prognosis of epithelial ovarian cancer is poor in part due to the high frequency of chemoresistance. Recent evidence points to the Toll-like receptor-4 (TLR4), and particularly its adaptor protein MyD88, as one potential mediator of this resistan
Externí odkaz:
https://doaj.org/article/208a05f77739491a8afed939f68cee69
Autor:
Christopher J Sweeney, Andrew J Martin, Martin R Stockler, Stephen Begbie, Leanna Cheung, Kim N Chi, Simon Chowdhury, Mark Frydenberg, Lisa G Horvath, Anthony M Joshua, Nicola J Lawrence, Gavin Marx, John McCaffrey, Ray McDermott, Margaret McJannett, Scott A North, Francis Parnis, Wendy Parulekar, David W Pook, Martin Neil Reaume, Shahneen K Sandhu, Alvin Tan, Thean Hsiang Tan, Alastair Thomson, Francisco Vera-Badillo, Scott G Williams, Diana Winter, Sonia Yip, Alison Y Zhang, Robert R Zielinski, Ian D Davis, Ehtesham Abdi, Suzanne Allan, Patricia Bastick, Robert Blum, Karen Briscoe, Daniel Brungs, Sean Bydder, Bala Renuka Chittajallu, Michelle Cronk, Katharine Cuff, Anthony Dowling, Matthew George, Lisa Horvath, Elizabeth Hovey, Anthony Joshua, Narayan Karanth, Ganessan Kichenadasse, Laurence Krieger, Maitham Mathlum, Louise Nott, Zulfiquer Otty, David Pook, Shahneen Sandhu, Sanjeev Sewak, Amanda Stevanovic, Martin Stockler, Aneta Suder, Hsiang Tan, Javier Torres, Simon Troon, Craig Underhill, Andrew Weickhardt, Robert Zielinski, Tahir Abbas, Ghadeer Anan, Chris Booth, Holly Campbell, Kim Chi, Joseph Chin, Edmond Chouinard, Bryan Donnelly, Darrel Drachenberg, Amir Faghih, Antonio Finelli, Sebastien Hotte, Krista Noonan, Scott North, Mohammad Rassouli, Neil Reaume, Ricardo Rendon, Fred Saad, Evgeny Sadikov, Eric Vigneault, Pawel Zalewski, Patrick Morris, Miriam O'Connor, Paul Donnellan, Dearbhaile O'Donnell, Jim Edwards, Peter Fong, Simon Crabb, Omar Khan, Vincent Khoo, Graham Macdonald, Heather Payne, Angus Robinson, Jonathon Shamash, John Staffurth, Carys Thomas
Publikováno v:
The Lancet Oncology. 24:323-334
Autor:
Gráinne Sheill, Lauren Brady, Brian Hayes, Anne-Marie Baird, Emer Guinan, Rishabh Vishwakarma, Caroline Brophy, Tatjana Vlajnic, Orla Casey, Verena Murphy, John Greene, Emma Allott, Juliette Hussey, Fidelma Cahill, Mieke Van Hemelrijck, Nicola Peat, Lorelei Mucci, Moya Cunningham, Liam Grogan, Thomas Lynch, Rustom P. Manecksha, John McCaffrey, Dearbhaile O’Donnell, Orla Sheils, John O’Leary, Sarah Rudman, Ray McDermott, Stephen Finn
Publikováno v:
Sheill, G, Brady, L, Hayes, B, Baird, A-M, Guinan, E, Vishwakarma, R, Brophy, C, Vlajnic, T, Casey, O, Murphy, V, Greene, J, Allott, E, Hussey, J, Cahill, F, Van Hemelrijck, M, Peat, N, Mucci, L, Cunningham, M, Grogan, L, Lynch, T, Manecksha, R P, McCaffrey, J, O'Donnell, D, Sheils, O, O'Leary, J, Rudman, S, McDermott, R & Finn, S 2023, ' ExPeCT: a randomised trial examining the impact of exercise on quality of life in men with metastatic prostate cancer ', Supportive Care in Cancer, vol. 31, no. 5, 292 . https://doi.org/10.1007/s00520-023-07740-4
Purpose All patients living with cancer, including those with metastatic cancer, are encouraged to be physically active. This paper examines the secondary endpoints of an aerobic exercise intervention for men with metastatic prostate cancer. Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80e0338328689323a3db82f84b68a162
https://pure.qub.ac.uk/en/publications/1fa7f6e0-5759-4038-956f-f8aba9536dc5
https://pure.qub.ac.uk/en/publications/1fa7f6e0-5759-4038-956f-f8aba9536dc5
Autor:
Ignace Vergote, Antonio Gonzalez-Martin, Domenica Lorusso, Charlie Gourley, Mansoor Raza Mirza, Jean-Emmanuel Kurtz, Aikou Okamoto, Kathleen Moore, Frédéric Kridelka, Iain McNeish, Alexander Reuss, Bénédicte Votan, Andreas du Bois, Sven Mahner, Isabelle Ray-Coquard, Elise C Kohn, Jonathan S Berek, David S P Tan, Nicoletta Colombo, Rongyu Zang, Nicole Concin, Dearbhaile O'Donnell, Alejandro Rauh-Hain, C Simon Herrington, Christian Marth, Andres Poveda, Keiichi Fujiwara, Gavin C E Stuart, Amit M Oza, Michael A Bookman, Christoph Grimm, Regina Berger, Ting-Chang Chang, Kazunori Ochiai, Val Gebski, Alison Davis, Philip Beale, Hannelore Denys, Vincent Vandecaveye, Francisco Jose Candido dos Reis, Maria Del Pilar Estevez Diz, Gavin Stuart, Helen MacKay, Mark Carey, David Cibula, Pavel Dundr (path), Oliver Dorigo, Jonathan Berek, Abu Saadeh, Ingrid Boere, Christianne Lok, Pluvio Coronado, Nelleke Ottevanger, David SP Tan, Joseph Ng, Antonio Gonzalez Martin, Ana Oaknin, Alejandro Perez Fidalgo, Karen Lu, Carlos López-Zavala, Eva María Gómez-García, Xavier Paoletti, Florence Joly, Michael Bookman, Rebecca Arend, Hiroyuki Fujiwara, Kosei Hasegawa, Ilan Bruchim, Dalia Tsoref, Katsutoshi Oda, Takayuki Enomoto, Dayana Michel, Hee-Seung Kim, Jung-Yun Lee, Asima Mukhopadhyay, Dionyssios Katsaros, Sandro Pignata, Giovanni Scambia, Elise Kohn, Jung-Min Lee, Shibani Nicum, Laura Farrelly, Jalid Sehouli, Maren Keller, Elena Braicu, Line Bjørge, Annika Auranen, Stephen Welch, Viola Heinzelmann, Patricia Roxburgh, Ros Glasspool, Jianqing Zhu
Publikováno v:
Lancet Oncology, 23, 8, pp. e374-e384
Vergote, I, Gonzalez-Martin, A, Lorusso, D, Gourley, C, Raza Mirza, M, Kurtz, J-E, Okamoto, A, Moore, K, Kridelka, F, McNeish, I, Reuss, A, Votan, B, du Bois, A, Mahner, S, Ray-Coquard, I, C. Kohn, E, S Berek, J, SP Tan, D, Colombo, N, Zang, R, Concin, N, O'Donnell, D, Rauh-Hain, A, Herrington, C S, Marth, C, Poveda, A, Fujiwara, K, C.E Stuart, G, Oza, A & Bookman, M A 2022, ' Clinical research in ovarian cancer: consensus recommendations from the Gynecologic Cancer InterGroup ', The Lancet Oncology, vol. 23, no. 8, pp. e374-e384 . https://doi.org/10.1016/S1470-2045(22)00139-5
Lancet Oncology, 23, e374-e384
Vergote, I, Gonzalez-Martin, A, Lorusso, D, Gourley, C, Raza Mirza, M, Kurtz, J-E, Okamoto, A, Moore, K, Kridelka, F, McNeish, I, Reuss, A, Votan, B, du Bois, A, Mahner, S, Ray-Coquard, I, C. Kohn, E, S Berek, J, SP Tan, D, Colombo, N, Zang, R, Concin, N, O'Donnell, D, Rauh-Hain, A, Herrington, C S, Marth, C, Poveda, A, Fujiwara, K, C.E Stuart, G, Oza, A & Bookman, M A 2022, ' Clinical research in ovarian cancer: consensus recommendations from the Gynecologic Cancer InterGroup ', The Lancet Oncology, vol. 23, no. 8, pp. e374-e384 . https://doi.org/10.1016/S1470-2045(22)00139-5
Lancet Oncology, 23, e374-e384
Contains fulltext : 283536.pdf (Publisher’s version ) (Closed access) The Gynecologic Cancer InterGroup (GCIG) sixth Ovarian Cancer Conference on Clinical Research was held virtually in October, 2021, following published consensus guidelines. The g
Autor:
Alon D. Altman, Charlie Gourley, John Butler, Gregg Nelson, Orla McNally, Dearbhaile O'Donnell, Citadel J Cabasag, Ewa Zotow, Janice S. Kwon, Michael Fung-Kee-Fung, Peter Sykes, Andy Nordin, Gunnar B. Kristensen, Neville F. Hacker, Louise Hanna, Samantha Harrison, Scott Fegan, Claus Høgdall, Charles H Norell, Paul A. Cohen, Tine H. Schnack, James Bentley, Rhonda Farrell
Publikováno v:
International Journal of Gynecological Cancer
Norell, C H, Butler, J, Farrell, R, Altman, A, Bentley, J, Cabasag, C J, Cohen, P A, Fegan, S, Fung-Kee-Fung, M, Gourley, C, Hacker, N F, Hanna, L, Høgdall, C K, Kristensen, G, Kwon, J, McNally, O, Nelson, G, Nordin, A, O'Donnell, D, Schnack, T, Sykes, P H, Zotow, E & Harrison, S 2020, ' Exploring international differences in ovarian cancer treatment : A comparison of clinical practice guidelines and patterns of care ', International Journal of Gynecological Cancer, vol. 30, no. 11, pp. 1748-1756 . https://doi.org/10.1136/ijgc-2020-001403
H. Norell, C, Butler, J, Farrell, R, Altman, A, Bentley, J, J. Cabasag, C, A. Cohen, P, Fegan, S, Fung-Kee-Fung, M, Gourley, C, Hacker, N, Hanna, L, Hoegdall, C, Kristensen, G, Kwon, J, McNally, O, Nelson, G, Nordin, A, O'Donnell, D, Schnack, T, Sykes, P, Zotow, E & Harrison, S 2020, ' Exploring international differences in ovarian cancer treatment: A comparison of clinical practice guidelines and patterns of care ', International Journal of Gynecological Cancer . https://doi.org/10.1136/ijgc-2020-001403
Norell, C H, Butler, J, Farrell, R, Altman, A, Bentley, J, Cabasag, C J, Cohen, P A, Fegan, S, Fung-Kee-Fung, M, Gourley, C, Hacker, N F, Hanna, L, Høgdall, C K, Kristensen, G, Kwon, J, McNally, O, Nelson, G, Nordin, A, O'Donnell, D, Schnack, T, Sykes, P H, Zotow, E & Harrison, S 2020, ' Exploring international differences in ovarian cancer treatment : A comparison of clinical practice guidelines and patterns of care ', International Journal of Gynecological Cancer, vol. 30, no. 11, pp. 1748-1756 . https://doi.org/10.1136/ijgc-2020-001403
H. Norell, C, Butler, J, Farrell, R, Altman, A, Bentley, J, J. Cabasag, C, A. Cohen, P, Fegan, S, Fung-Kee-Fung, M, Gourley, C, Hacker, N, Hanna, L, Hoegdall, C, Kristensen, G, Kwon, J, McNally, O, Nelson, G, Nordin, A, O'Donnell, D, Schnack, T, Sykes, P, Zotow, E & Harrison, S 2020, ' Exploring international differences in ovarian cancer treatment: A comparison of clinical practice guidelines and patterns of care ', International Journal of Gynecological Cancer . https://doi.org/10.1136/ijgc-2020-001403
IntroductionThe International Cancer Benchmarking Partnership demonstrated international differences in ovarian cancer survival, particularly for women aged 65–74 with advanced disease. These findings suggest differences in treatment could be contr
Autor:
Brendan, Ffrench, Claudia, Gasch, Karsten, Hokamp, Cathy, Spillane, Gordon, Blackshields, Thamir Mahmoud, Mahgoub, Mark, Bates, Louise, Kehoe, Aoibhinn, Mooney, Ronan, Doyle, Brendan, Doyle, Dearbhaile, O'Donnell, Noreen, Gleeson, Bryan T, Hennessy, Britta, Stordal, Ciaran, O'Riain, Helen, Lambkin, Sharon, O'Toole, John J, O'Leary, Michael F, Gallagher
Publikováno v:
Cell Death & Disease
It is long established that tumour-initiating cancer stem cells (CSCs) possess chemoresistant properties. However, little is known of the mechanisms involved, particularly with respect to the organisation of CSCs as stem-progenitor-differentiated cel
Publikováno v:
BMJ case reports. 2009
This is a case of a 69-year-old woman who was diagnosed as having metastatic leiomyosarcoma. She presented with multiple lung opacities on plain films and CT scans following resection of a high-grade leiomyosarcoma of the uterus 16 months earlier. Th
Autor:
David J, Easty, Steven G, Gray, Kenneth J, O'Byrne, Dearbhaile, O'Donnell, Dorothy C, Bennett
Publikováno v:
Pigment cellmelanoma research. 24(3)
Receptor tyrosine kinases (RTKs) and their downstream signalling pathways have long been hypothesized to play key roles in melanoma development. A decade ago, evidence was derived largely from animal models, RTK expression studies and detection of ac