Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Dear Tn"'
Autor:
Diggle, CP, Martinez-Garay, I, Molnar, Z, Brinkworth, MH, White, E, Fowler, E, Hughes, R, Hayward, BE, Carr, IM, Watson, CM, Crinnion, L, Asipu, A, Woodman, B, Coletta, PL, Markham, AF, Dear, TN, Bonthron, DT, Peckham, M, Morrison, EE, Sheridan, E, Guo, X
Publikováno v:
PloS One. 12(4)
Tubulin alpha 8 (Tuba8) is the most divergent member of the highly conserved alpha tubulin family, and uniquely lacks two key post-translational modification sites. It is abundantly expressed in testis and muscle, with lower levels in the brain. We p
Autor:
Abraham, S, Scarcia, M, Bagshaw, R, McMahon, K, Grant, G, Harvey, T, Yeo, M, Esteves, FOG, Thygesen, HH, Jones, PF, Spiers, V, Hanby, AM, Selby, PJ, Lorger, M, Dear, TN, Pawson, T, Marshall, CJ, Mavria, G
Publikováno v:
Abraham, S, Scarcia, M, Bagshaw, R D, McMahon, K, Grant, G, Harvey, T, Yeo, M, Esteves, F O G, Thygesen, H H, Jones, P F, Speirs, V, Hanby, A M, Selby, P J, Lorger, M, Dear, T N, Pawson, T, Marshall, C J & Mavria, G 2015, ' A Rac/Cdc42 exchange factor complex promotes formation of lateral filopodia and blood vessel lumen morphogenesis. ', Nature Communications, vol. 6, 7286 . https://doi.org/10.1038/ncomms8286
During angiogenesis, Rho-GTPases influence endothelial cell migration and cell-cell adhesion; however it is not known whether they control formation of vessel lumens, which are essential for blood flow. Here, using an organotypic system that recapitu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e5887d439b75c4b51f32ef900b66d270
https://www.research.manchester.ac.uk/portal/en/publications/a-raccdc42-exchange-factor-complex-promotes-formation-of-lateral-filopodia-and-blood-vessel-lumen-morphogenesis(76445d51-ddd6-4605-971a-2b2101e43b86).html
https://www.research.manchester.ac.uk/portal/en/publications/a-raccdc42-exchange-factor-complex-promotes-formation-of-lateral-filopodia-and-blood-vessel-lumen-morphogenesis(76445d51-ddd6-4605-971a-2b2101e43b86).html
Autor:
Li, J, Hou, B, Tumova, S, Muraki, K, Bruns, A, Ludlow, MJ, Sedo, A, Hyman, AJ, McKeown, L, Young, RS, Yuldasheva, NY, Majeed, Y, Wilson, LA, Rode, B, Bailey, MA, Kim, HR, Fu, Z, Carter, DAL, Bilton, J, Imrie, H, Ajuh, P, Dear, TN, Cubbon, RM, Kearney, MT, Prasad, KR, Evans, PC, Ainscough, JFX, Beech, DJ
The mechanisms by which physical forces regulate endothelial cells to determine the complexities of vascular structure and function are enigmatic1, 2, 3, 4, 5. Studies of sensory neurons have suggested Piezo proteins as subunits of Ca2+-permeable non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::90ca06d946391d0337daeb429c76b1b9
Publikováno v:
Mammalian Genome. 10:318-321
Autor:
Dear Tn
Publikováno v:
Mammalian genome : official journal of the International Mammalian Genome Society. 11(11)
Publikováno v:
Genomics. 59(2)
Calpains are a superfamily of related proteins, some of which have been shown to function as calcium-dependent cysteine proteases. In mammals, eight different calpains have been identified. We report the identification of a new mammalian calpain gene
Publikováno v:
Immunogenetics. 46(6)
The differentiation of primitive epithelial precursor cells in the thymic primordium into subcapsular, cortical, and medullary epithelial cells of the mature thymus requires the activity of the nude gene product Whn. Whn is also required for proper k
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