Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Deanne Crowell"'
Autor:
Deanne Crowell, Michael D. Tufano, Kennan C. Marsh, Kristine B. Berst, Jacob J. Plattner, Lisa A. Hasvold, Daniel T. W. Chu, Qun Li, Angela M. Nilius, Linus L. Shen, Weibo Wang, Kathleen Raye, Akiyo K. Claiborne, Jeff Alder, Robert K. Flamm
Publikováno v:
Bioorganicmedicinal chemistry letters. 8(15)
The 8-position side chain of 2-pyridones is believed to be involved in the binding with bacterial DNA gyrase to form the ternary complex, making them very important for the activity of 2-pyridones. A series of 2-pyridones having fluoro-substituted am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93775667e7384571f427311a12afcffb
https://pubmed.ncbi.nlm.nih.gov/9873465
https://pubmed.ncbi.nlm.nih.gov/9873465
Autor:
Qun Li, Daniel T. W. Chu, Akiyo Claiborne, Curt S. Cooper, Cheuk M. Lee, Kathleen Raye, Kristine B. Berst, Pamela Donner, Weibo Wang, Lisa Hasvold, Anthony Fung, Zhenkun Ma, Michael Tufano, Robert Flamm, Linus L. Shen, John Baranowski, Angela Nilius, Jeff Alder, Jonathan Meulbroek, Kennan Marsh, DeAnne Crowell, Yuhua Hui, Louis Seif, Laura M. Melcher, Rodger Henry, Steven Spanton, Ramin Faghih, Larry L. Klein, S. Ken Tanaka, Jacob J. Plattner
Publikováno v:
Journal of medicinal chemistry. 39(16)
Two novel series of 2-pyridones were synthesized by transposition of the nitrogen of 4-quinolones to the bridgehead position. This subtle interchange of the nitrogen atom with a carbon atom yielded two novel heterocyclic nuclei, pyrido[1,2-alpha]pyri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a50a29d2238b79a28999613a1a9301d
https://pubmed.ncbi.nlm.nih.gov/8759628
https://pubmed.ncbi.nlm.nih.gov/8759628