Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Deanne Rudd"'
Autor:
Ray T. McClain, Joseph M. Pawluczyk, Craig W. Lindsley, Chris Denicola, James Mulhearn, Deanne Rudd
Publikováno v:
Tetrahedron Letters. 48:1497-1501
Microwave heating of high-loading TEMPO-methyl resin with functionalized styrenyl monomers in an ADVANCER™ preparative scale microwave synthesizer affords larger resin beads (>375 μm) via living free radical polymerization (LFRP). Unlike homogeneo
Autor:
John T. Sisko, Kenneth D. Anderson, Meiquing Lu, Ming-Tain Lai, Theresa M. Williams, Vandna Munshi, Carolyn Bahnck, Yuexia Liang, Bang-Lin Wan, Gregory Moyer, Thomas J. Tucker, Michael W. Miller, Joe P. Vacca, Rebecca Perlow-Poehnelt, John Jin Lim, Daniel J. DiStefano, Rosa I. Sanchez, Peter J. Felock, Dai-Shi Su, Sinoeun Touch, Deanne Rudd, Elizabeth Tinney, Saggar Sandeep A, Neville J. Anthony, Mary Beth Young, Jessica A. Flynn
Publikováno v:
Bioorganicmedicinal chemistry letters. 20(15)
Biaryl ethers were recently reported as potent NNRTIs. Herein, we disclose a detailed effort to modify the previously reported compound 1. We have designed and synthesized a series of novel pyrazole derivatives as a surrogate for pyrazolopyridine mot
Autor:
Vandna Munshi, Joe P. Vacca, Sinoeun Touch, Gregory Moyer, Jessica A. Flynn, Peter J. Felock, Dai-Shi Su, Theresa M. Williams, Deanne Rudd, Neville J. Anthony, Meiquing Lu, Michael W. Miller, Carolyn Bahnck, Rebecca Perlow-Poehnelt, Daniel J. DiStefano, John Jin Lim, Rosa I. Sanchez, Bang-Lin Wan, Kenneth D. Anderson, Elizabeth Tinney, Ming-Tain Lai, Mary Beth Young, Yuexia Liang
Publikováno v:
Journal of medicinal chemistry. 52(22)
Biaryl ethers were recently reported as potent NNRTIs. Herein we disclose a detailed SAR study that led to the biaryl ether 6. This compound possessed excellent potency against WT RT and key clinically observed RT mutants and had an excellent pharmac
Autor:
Ming-Tain Lai, Mary Beth Young, Michael W. Miller, Peter J. Felock, Theresa M. Williams, Carolyn Bahnck, Dai-Shi Su, Maricel Torrent, Vandna Munshi, Sinoeun Touch, Meiqing Lu, Rebecca Perlow-Poehnelt, Youwei Yan, Daniel J. DiStefano, Deanne Rudd, Kenneth D. Anderson, Joe P. Vacca, John Jin Lim, Rosa I. Sanchez, Bang-Lin Wan, Elizabeth Tinney, Yuexia Liang, Gregory Moyer, Sridhar Prasad, Jessica A. Flynn, Neville J. Anthony
Publikováno v:
Bioorganicmedicinal chemistry letters. 19(17)
Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are key elements of multidrug regimens, called HAART (Highly Active Antiretroviral Therapy), that are used to treat HIV-1 infections. Elucidation of the structure-activity relationships of the
Autor:
Dai-Shi Su, John J. Lim, Elizabeth Tinney, Bang-Lin Wan, Mary Beth Young, Kenneth D. Anderson, Deanne Rudd, Vandna Munshi, Carolyn Bahnck, Peter J. Felock, Meiquing Lu, Ming-Tain Lai, Sinoeun Touch, Gregory Moyer, Daniel J DiStefano, Jessica A. Flynn, Yuexia Liang, Rosa Sanchez, Rebecca Perlow-Poehnelt, Mike Miller
Publikováno v:
Journal of Medicinal Chemistry; Nov2009, Vol. 52 Issue 22, p7163-7169, 7p