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pro vyhledávání: '"Deanna Y. Lin"'
Autor:
Marsha C. Lampi, Francois Bordeleau, Zachary E. Goldblatt, Andrés J. García, Casey M. Kraning-Rush, Aniqua Rahman, Deanna Y. Lin, Cynthia A. Reinhart-King, Shawn P. Carey
Publikováno v:
Molecular Biology of the Cell. 27:1431-1441
During metastasis, cells can use proteolytic activity to form tube-like “microtracks” within the extracellular matrix (ECM). Using these microtracks, cells can migrate unimpeded through the stroma. To investigate the molecular mechanisms of micro
Autor:
Aniqua, Rahman, Shawn P, Carey, Casey M, Kraning-Rush, Zachary E, Goldblatt, Francois, Bordeleau, Marsha C, Lampi, Deanna Y, Lin, Andrés J, García, Cynthia A, Reinhart-King
Publikováno v:
Molecular Biology of the Cell
Cells can maneuver through 3D matrices by using tracks that exist in the matrix. The focal adhesion protein vinculin mediates the unidirectional movement through these tracks. Moreover, vinculin also promotes directional migration in 2D and 3D matric