Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Deanna S. Lane"'
Autor:
Karen Hayes, Reina N. Fuji, Lisa L. Shafer, Saileta Prabhu, William J. Meilandt, Keith R. Hildebrand, Ryan J. Watts, Thomas Keene, Jessica Couch, Blair Wilson, Jasvinder K. Atwal, Janice A. Maloney, Ann L. Daugherty, Kapil Gadkar, Kimberly Scearce-Levie, Kristin R. Wildsmith, Yanmei Lu, Andrew Kosky, Marisa Goo, Robert C. Switzer, Kun Peng, Eric Adams, Deepak R. Thakker, Pamela Chan, Deanna S. Lane, Lisa Jungbauer Nikolas, Hilda Solanoy, Daniela Bumbaca Yadav
Publikováno v:
British Journal of Pharmacology. 174:4173-4185
Background and Purpose The potential for therapeutic antibody treatment of neurological diseases is limited by poor penetration across the blood–brain barrier. I.c.v. delivery is a promising route to the brain; however, it is unclear how efficientl
Autor:
Marcy R. Weatherspoon, Lisa L. Shafer, Thomas Keene, Jonathan Harrison, Deepak R. Thakker, William F. Kaemmerer, Deanna S. Lane, Gregory R. Stewart
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 106(11)
Although immunization against amyloid-β (Aβ) holds promise as a disease-modifying therapy for Alzheimer disease (AD), it is associated with an undesirable accumulation of amyloid in the cerebrovasculature [i.e., cerebral amyloid angiopathy (CAA)] a