Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Deanna M Arble"'
Autor:
Aaron A. Jones, Deanna M. Arble
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
In vertebrate animals, the automatic, rhythmic pattern of breathing is a highly regulated process that can be modulated by various behavioral and physiological factors such as metabolism, sleep–wake state, activity level, and endocrine signaling. E
Externí odkaz:
https://doaj.org/article/acc0817f64414a47a517658da6533ddc
Autor:
Gabriella M. Marino, Deanna M. Arble
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Sleep and circadian disruption are associated with an increased risk of metabolic disease, including obesity and diabetes. Mounting evidence indicates that misaligned and/or non-functional clock proteins in peripheral tissues critically contribute to
Externí odkaz:
https://doaj.org/article/fb0ae7f670784fc79b9350c403c8da2a
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Background: Intermittent hypoxia (IH), a key characteristic of obstructive sleep apnea, is independently associated with cardiometabolic impairment. While endogenous leptin levels may provide cardioprotective effects against hypoxia, leptin resistanc
Externí odkaz:
https://doaj.org/article/1de6a2a415dc4cc99787c0ee57594f76
Autor:
Deanna M. Arble, Chelsea R. Hutch, Hannah Hafner, Daria Stelmak, Kyle Leix, Joyce Sorrell, Joshua W. Pressler, Brigid Gregg, Darleen A. Sandoval
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 324:E217-E225
We examined the role of Gcg on β-cell function under normal and high glucose conditions. GcgNull mice had decreased glucose-stimulated insulin secretion, increased β-cell mass, and partial protection against STZ-induced hyperglycemia. Expression of
Publikováno v:
Function.
While the suprachiasmatic nucleus (SCN) controls 24-hour rhythms in breathing including minute ventilation (VE), the mechanisms by which the SCN drives these daily changes are not well understood. Moreover, the extent to which the circadian clock reg
Autor:
Sarah N. Framnes, Deanna M. Arble
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Obstructive sleep apnea (OSA) is a common sleep disorder, effecting 17% of the total population and 40–70% of the obese population (1, 2). Multiple studies have identified OSA as a critical risk factor for the development of obesity, diabetes, and
Externí odkaz:
https://doaj.org/article/27584434709745d482a530a8e37ece81
Publikováno v:
The FASEB Journal. 36
Autor:
Aaron A. Jones, Lauren R. Nelson, Nakia A. Chappelle, Deanna M. Arble, Gabriella M. Marino, Deborah A. M. Joye
Publikováno v:
Journal of Biological Rhythms. 36:346-358
Obstructive sleep apnea is a common sleep disorder that increases risk for cardiovascular disease and mortality. The severity of sleep-disordered breathing in obstructive sleep apnea patients fluctuates with the seasons, opening the possibility that
Autor:
Sarah N. Framnes-DeBoer, Randy J. Seeley, Darleen A. Sandoval, Ellen Bakke, Deanna M. Arble, Hannah Peterson, Suma Yalamanchili
Publikováno v:
Am J Physiol Endocrinol Metab
Bromocriptine, a dopamine D2 receptor agonist originally used for the treatment of hyperprolactinemia, is largely successful in reducing hyperglycemia and improving glucose tolerance in type 2 diabetics. However, the mechanism behind bromocriptine’
Autor:
Lauren R. Nelson, Michelle Y. Kang, Aaron A. Jones, Sarah N. Framnes-DeBoer, Deanna M. Arble, Kat Propsom
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 321(4)
Sleep apnea is a common sleep disorder characterized by periodic breathing cessation and intermittent hypoxia (IH). Although previous studies have demonstrated that IH alone can influence metabolic outcomes such as body weight, it remains unclear how