Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Deanna Langager"'
Publikováno v:
Disease Models & Mechanisms, Vol 5, Iss 2, Pp 191-199 (2012)
SUMMARY BTN1, the yeast homolog to human CLN3 (which is defective in Batten disease), has been implicated in the regulation of vacuolar pH, potentially by modulating vacuolar-type H+-ATPase (V-ATPase) activity. However, we report that Btn1p and the V
Externí odkaz:
https://doaj.org/article/3c6d4f9fa3f34a1588376fb65621f81b
Autor:
Leslie A. Leinwand, Deanna Langager
Publikováno v:
Circulation Research. 121
Introduction: Cardiac hypertrophy is initially, a compensatory mechanism to maintain cardiac output when there is an increased load on the heart. However, if cardiac hypertrophy persists for an extended time, there can be maladaptive changes to the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16b9cb7ea57efe41277afdae80ddb7dd
https://doi.org/10.1161/res.121.suppl_1.157
https://doi.org/10.1161/res.121.suppl_1.157
The proteasome is assembled via the nine-subunit lid, nine-subunit base, and 28-subunit core particle (CP). Previous work has shown that the chaperones Rpn14, Nas6, Hsm3, and Nas2 each bind a specific ATPase subunit of the base and antagonize base–
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b9b45723a643d57e8183db86c9cd1f5
https://europepmc.org/articles/PMC5321026/
https://europepmc.org/articles/PMC5321026/
Publikováno v:
Disease Models & Mechanisms
Disease Models & Mechanisms, Vol 5, Iss 2, Pp 191-199 (2012)
Disease Models & Mechanisms, Vol 5, Iss 2, Pp 191-199 (2012)
SUMMARY BTN1, the yeast homolog to human CLN3 (which is defective in Batten disease), has been implicated in the regulation of vacuolar pH, potentially by modulating vacuolar-type H+-ATPase (V-ATPase) activity. However, we report that Btn1p and the V
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e91f8af8c5e3a15a0cdf9cd7e5a34821
http://europepmc.org/articles/PMC3291640
http://europepmc.org/articles/PMC3291640