Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Deanna L. Taylor"'
Publikováno v:
Journal of Vocational Rehabilitation. 44:163-173
BACKGROUND: Interagency collaboration has been identified as one variable predicting successful post-school outcomes for youth with disabilities (Test et al., 2009). However, at times and in certain contexts, collaboration between these disciplines h
Autor:
T. P. Obrenovitch, Deanna L. Taylor, Lindsay Symon, Jutta Urenjak, John B. Clark, Douglas A. Richards, Siân E. C. Davies
Publikováno v:
Journal of Neurochemistry. 62:2349-2355
The purpose of this study was to determine the extracellular concentrations of N-acetylaspartate (NAA) in the rat cerebral cortex, striatum, and hippocampus of halothane-anaesthetised rats by intracerebral microdialysis, and to examine the effects of
Publikováno v:
Brain Pathol
In focal brain lesions, alterations in blood flow and cerebral metabolism can be detected in brain areas remote from the primary injury. The cellular consequences of this phenomenon, originally termed diaschisis, are not fully understood. Here, we re
Publikováno v:
Journal of Neurochemistry. 92:1363-1376
Microglial activation is implicated in the neurotoxicity of neurodegenerative diseases. Raised intracerebral levels of albumin are associated with the pathology of Alzheimer's disease, multiple sclerosis, and stroke where blood-brain barrier damage i
Publikováno v:
Journal of Neurochemistry. 90:89-101
Microglia, the resident macrophage of the brain, can release substances that aid neuronal development, differentiation and survival. We have investigated the effects of non-activated microglia on the survival of cultured rat cerebellar granule neuron
Publikováno v:
Journal of Neurochemistry. 82:1179-1191
Regulation of microglial reactivity and neurotoxicity is critical for neuroprotection in neurodegenerative diseases. Here we report that microglia possess functional group II metabotropic glutamate receptors, expressing mRNA and receptor protein for
Autor:
David Baker, Jennifer M. Pocock, John P. Leonard, M. Louise Cuzner, Gareth Pryce, Zubair Ahmed, Deanna L. Taylor, Anne I. Doward
Publikováno v:
The American Journal of Pathology. 161:1577-1586
Axonal loss, already present in the acute and first relapse phases of experimental allergic encephalomyelitis (EAE) in the ABH mouse, only becomes apparent in the third relapse in the interleukin-12 model of relapsing EAE in the Lewis rat. Caspase-1
Autor:
Nicholas D. Mazarakis, Jennifer M. Pocock, Catherine Sarraf, Ursula Felderhoff-Mueser, Deanna L. Taylor, Huseyin Mehmet, Mary Kozma, Pierre Rustin, Kirsty Greenwood, Philippe Jouvet, Umesh Joashi, A. David Edwards
Publikováno v:
Molecular Biology of the Cell. 11:1919-1932
Maple syrup urine disease (MSUD) is an inborn error of metabolism caused by a deficiency in branched chain α-keto acid dehydrogenase that can result in neurodegenerative sequelae in human infants. In the present study, increased concentrations of MS
Autor:
Deanna L. Taylor, Huseyin Mehmet, K. Aguan, J. E. McKenzie, AD Edwards, EB Cady, Xu Yue, Carl P. Weiner, R. M. Blumberg
Publikováno v:
Pediatric Research. 46:224-231
This study addressed the hypothesis that the delayed impairment in cerebral energy metabolism that develops 10-24 h after transient hypoxia-ischemia in the developing brain is mediated by induction of increased nitric oxide synthesis. Four groups of
Autor:
Deanna L. Taylor, Nicholas D. Mazarakis, Umesh Joashi, Mary Kozma, A. D. Edwards, Kirsty Greenwood, Huseyin Mehmet
Publikováno v:
European Journal of Neuroscience. 11:91-100
Transient unilateral forebrain hypoxia-ischaemia (HI) in 14-day-old rats produces infarction and delayed neuronal death in the frontal cortex. Cell death can also be observed in regions distant from the primary injury, a phenomenon known as diaschisi