Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Deanna L. Newcomb"'
Publikováno v:
Reproductive Toxicology. 58:160-173
The reproductive and developmental toxicity of ixekizumab, a selective inhibitor of interleukin-17A (IL-17A), was assessed in the following studies in cynomolgus monkeys: fertility (3-month dosing), embryo-fetal development (EFD; dosing from gestatio
Autor:
Julie A. Zalikowski, Graeme J. Moffat, Deanna L. Newcomb, Gary J. Chellman, Mary Ellen McNerney, Kary E. Thompson
Publikováno v:
Reproductive toxicology (Elmsford, N.Y.). 59
Given concern about potential embryo-fetal harm following seminal exposure to drugs with teratogenic potential, pharmaceutical companies use theoretical calculations to estimate seminal concentrations, maternal exposure, and distribution across the p
Autor:
William J, Breslin, Kim G, Hilbish, Jennifer A, Martin, Carolyn A, Halstead, Deanna L, Newcomb, Gary J, Chellman
Publikováno v:
Birth defects research. Part B, Developmental and reproductive toxicology. 104(3)
Tabalumab, a human IgG4 monoclonal antibody (mAb) with neutralizing activity against both soluble and membrane B-cell activating factor (BAFF), has been under development for the treatment of autoimmune diseases. The purpose of this study was to dete
Autor:
Deanna L. Newcomb, Sinisa Nadjsombati, Gregory I. Frost, Walter H. Bee, Allan Hoberman, Monica L. Zepeda
Publikováno v:
Matrix Biology. 27:23