Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Deanna J, Lamont"'
Autor:
Felix Scheuplein, Deanna J Lamont, Matthew E Poynter, Jonathan E Boyson, David Serreze, Lennart K A Lundblad, Robert Mashal, Robert Schaub
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140729 (2015)
Invariant Natural Killer T (iNKT) cells are a T cell subset expressing an invariant T Cell Receptor (TCR) that recognizes glycolipid antigens rather than peptides. The cells have both innate-like rapid cytokine release, and adaptive-like thymic posit
Externí odkaz:
https://doaj.org/article/6980faa195b94b189f29fc0fda87c8e0
Autor:
Brittney N. Newby, David V. Serreze, Cheng Ye, John P. Driver, Yi-Guang Chen, Clayton E. Mathews, Harold D. Chapman, Jeremy J. Racine, Todd M. Brusko, Deanna J. Lamont, Caroline M. Leeth
Publikováno v:
Diabetes. 66:710-721
Type 1 diabetes development in the NOD mouse model is widely reported to be dependent on high-level production by autoreactive CD4+ and CD8+ T cells of interferon-γ (IFN-γ), generally considered a proinflammatory cytokine. However, IFN-γ can also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03cf21022fb826572ac92919c0620176
https://doi.org/10.2337/db16-0846
https://doi.org/10.2337/db16-0846
Autor:
Jennifer Allocco, Tim Stearns, Aron M. Geurts, Yi-Guang Chen, Maximiliano Presa, Ingo Schmitz, Deanna J. Lamont, Harold D. Chapman, David V. Serreze, Vishal Kumar Sarsani, Jennifer R. Dwyer, Jeremy J. Ratiu, Jeremy J. Racine
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950)
In both NOD mice and humans, the development of type 1 diabetes (T1D) is dependent in part on autoreactive CD8+ T cells recognizing pancreatic β cell peptides presented by often quite common MHC class I variants. Studies in NOD mice previously revea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3706ddd095e2b9a992612dbc351f4108
https://hdl.handle.net/10033/622048
https://hdl.handle.net/10033/622048
Autor:
Maximiliano, Presa, Jeremy J, Racine, Jennifer R, Dwyer, Deanna J, Lamont, Jeremy J, Ratiu, Vishal Kumar, Sarsani, Yi-Guang, Chen, Aron, Geurts, Ingo, Schmitz, Timothy, Stearns, Jennifer, Allocco, Harold D, Chapman, David V, Serreze
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 201(7)
In both NOD mice and humans, the development of type 1 diabetes (T1D) is dependent in part on autoreactive CD8(+) T-cells recognizing pancreatic ß-cell peptides presented by often quite common MHC class I variants. Studies in NOD mice previously rev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2642363c4e8e868bad33016b3708f1ff
https://pubmed.ncbi.nlm.nih.gov/30127089
https://pubmed.ncbi.nlm.nih.gov/30127089
Autor:
Jennifer R. Dwyer, Jeremy J. Racine, Tim Stearns, Jeremy J. Ratiu, Maximiliano Presa, Vishal Kumar Sarsani, Jennifer Allocco, David V. Serreze, Ingo Schmitz, Deanna J. Lamont, Aron M. Geurts, Yi-Guang Chen, Harold D. Chapman
In both NOD mice and humans, the development of type 1 diabetes (T1D) is dependent in part on autoreactive CD8+ T-cells recognizing pancreatic ß-cell peptides presented by often quite common MHC class I variants. Studies in NOD mice previously revea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f7e3f80f11bc6449fb2f90649ccd591
Autor:
David V. Serreze, P. Rajesh Kumar, Dibyendu Samanta, Teresa P. DiLorenzo, Thomas W.H. Kay, Caroline G. McPhee, Gayatri Mukherjee, Deanna J. Lamont, Steven C. Almo
Publikováno v:
The Journal of Immunology. 193:2135-2146
Self-reactive T cells must escape thymic negative selection to mediate pathogenic autoimmunity. In the NOD mouse model of autoimmune diabetes, several β cell–cytotoxic CD8 T cell populations are known, with the most aggressive of these represented
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::baf115fbc67abcd077839a43765d4d34
https://doi.org/10.4049/jimmunol.1400997
https://doi.org/10.4049/jimmunol.1400997
Autor:
John P, Driver, Jeremy J, Racine, Cheng, Ye, Deanna J, Lamont, Brittney N, Newby, Caroline M, Leeth, Harold D, Chapman, Todd M, Brusko, Yi-Guang, Chen, Clayton E, Mathews, David V, Serreze
Publikováno v:
Diabetes
Type 1 diabetes development in the NOD mouse model is widely reported to be dependent on high-level production by autoreactive CD4+ and CD8+ T cells of interferon-γ (IFN-γ), generally considered a proinflammatory cytokine. However, IFN-γ can also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a08420aa1e9309aa8877abe541b7df59
https://pubmed.ncbi.nlm.nih.gov/27920091
https://pubmed.ncbi.nlm.nih.gov/27920091
Autor:
Lennart K. A. Lundblad, David V. Serreze, Robert Mashal, Felix Scheuplein, Matthew E. Poynter, Jonathan E. Boyson, Deanna J. Lamont, Robert Schaub
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 10, p e0140729 (2015)
PLoS ONE, Vol 10, Iss 10, p e0140729 (2015)
Invariant Natural Killer T (iNKT) cells are a T cell subset expressing an invariant T Cell Receptor (TCR) that recognizes glycolipid antigens rather than peptides. The cells have both innate-like rapid cytokine release, and adaptive-like thymic posit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fc775c7d24219cbad15a3862652aab7
https://pubmed.ncbi.nlm.nih.gov/26474487
https://pubmed.ncbi.nlm.nih.gov/26474487
Vitamin D exerts important regulatory effects on the endocrine and immune systems. Autoimmune type 1 diabetes (T1D) development in the inbred NOD mouse strain can be accelerated by vitamin D insufficiency or suppressed by chronic treatment with high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0e4f489d90a053bcd492935b550059c
https://europepmc.org/articles/PMC3230053/
https://europepmc.org/articles/PMC3230053/
Autor:
Paul F. Bradfield, Pilar Alcaide, Charles A. Parkos, Tony W. Liang, Beat A. Imhof, Monica Sircar, Deanna J. Lamont, Francis W. Luscinskas, Richard J. Fish, Gail Newton, Michel Aurrand-Lions, Lin Yang, Tanya N. Mayadas, Seema Sehrawat
Publikováno v:
Journal of Immunology, Vol. 178, No 9 (2007) pp. 5879-5887
Endothelial cell junctional adhesion molecule (JAM)-C has been proposed to regulate neutrophil migration. In the current study, we used function-blocking mAbs against human JAM-C to determine its role in human leukocyte adhesion and transendothelial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cb5c9deba1bdd0f9c457cc185f40982
https://pubmed.ncbi.nlm.nih.gov/17442972
https://pubmed.ncbi.nlm.nih.gov/17442972