Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Deanna Gotte"'
Autor:
Xiang-Yang Xue, Vladimir Majerciak, Aayushi Uberoi, Bong-Hyun Kim, Deanna Gotte, Xiongfong Chen, Maggie Cam, Paul F Lambert, Zhi-Ming Zheng
Publikováno v:
PLoS Pathogens, Vol 13, Iss 11, p e1006715 (2017)
Mouse papillomavirus type 1 (MmuPV1) provides, for the first time, the opportunity to study infection and pathogenesis of papillomaviruses in the context of laboratory mice. In this report, we define the transcriptome of MmuPV1 genome present in papi
Externí odkaz:
https://doaj.org/article/8471e1967fc34e55a3920e13b65b2066
Autor:
Donald L. Court, Alison J. Rattray, Ding J. Jin, Mikhail Bubunenko, Xintian Li, Maria L. Kireeva, Deanna Gotte, Mikhail Kashlev, Jorge A. Irizarry-Caro, Jeffrey N. Strathern, Carolyn Court
Publikováno v:
Genetics
We made a coupled genetic reporter that detects rare transcription misincorporation errors to measure RNA polymerase transcription fidelity in Escherichia coli. Using this reporter, we demonstrated in vivo that the transcript cleavage factor GreA, bu
Autor:
Vladimir Majerciak, Xiongfong Chen, Bong Hyun Kim, Zhi-Ming Zheng, Maggie Cam, Paul F. Lambert, Xiangyang Xue, Aayushi Uberoi, Deanna Gotte
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 13, Iss 11, p e1006715 (2017)
PLoS Pathogens, Vol 13, Iss 11, p e1006715 (2017)
Mouse papillomavirus type 1 (MmuPV1) provides, for the first time, the opportunity to study infection and pathogenesis of papillomaviruses in the context of laboratory mice. In this report, we define the transcriptome of MmuPV1 genome present in papi
Autor:
Alissa A. Hare, Timothy R. Welch, Jeffrey N. Strathern, Liang Xu, Dong Wang, Ji Hyun Shin, Peter B. Dervan, Wei Wang, Fei Yang, Benjamin C. Li, Jenny Chong, Deanna Gotte
RNA polymerase II (pol II) encounters numerous barriers during transcription elongation, including DNA strand breaks, DNA lesions, and nucleosomes. Pyrrole-imidazole (Py-Im) polyamides bind to the minor groove of DNA with programmable sequence specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::940e020de05acfdca9748b12e7a37fe9
https://resolver.caltech.edu/CaltechAUTHORS:20161020-165432331
https://resolver.caltech.edu/CaltechAUTHORS:20161020-165432331
Autor:
Deanna Gotte, Maria L. Kireeva, Lucyna Lubkowska, Jeffrey N. Strathern, Jordan D. Irvin, Francisco Malagon, Brenda Shafer, Mikhail Kashlev, Ding Jun Jin
Publikováno v:
Journal of Biological Chemistry. 288:2689-2699
The fidelity of RNA synthesis depends on both accurate template-mediated nucleotide selection and proper maintenance of register between template and RNA. Loss of register, or transcriptional slippage, is particularly likely on homopolymeric runs in
Autor:
Patrick Cramer, Jeffrey N. Strathern, Alan C. M. Cheung, Mikhail Kashlev, Maria L. Kireeva, Celine Walmacq, Thomas Carell, Chengcheng Ye, Lucyna Lubkowska, Deanna Gotte
Publikováno v:
Molecular Cell
Summary UV-induced cyclobutane pyrimidine dimers (CPDs) in the template DNA strand stall transcription elongation by RNA polymerase II (Pol II). If the nucleotide excision repair machinery does not promptly remove the CPDs, stalled Pol II creates a r
Autor:
Bart Scherens, Ning Lan, Steeve Veronneau, Anna Astromoff, Matt Curtiss, Ronald W. Davis, Jeffrey N. Strathern, Marleen Voet, Johannes H. Hegemann, Ankuta Lucau-Danila, Petra Ross-Macdonald, Adam M. Deutschbauer, Françoise Foury, Greg Schimmack, Daniel D. Shoemaker, Karen Davis, Rhonda Bangham, Darlene LaBonte, Christopher J. Roberts, Zelek S. Herman, Patrick Flaherty, Stefano Campanaro, Patrice Menard, Michael Snyder, Teresa R. Ward, Adam P. Arkin, Howard Bussey, Linda Riles, Yonghong Yang, Grace Yen, Guri Giaever, K. D. Entian, Kexin Yu, Elaine M. Youngman, Sharon Sookhai-Mahadeo, Jef D. Boeke, Reginald Storms, Daniel F. Jaramillo, Giorgio Valle, José L. Revuelta, Sally Dow, Mark Johnston, Matthias Rose, Mohamed El Bakkoury, Deanna Gotte, Hong Liao, Elizabeth A. Winzeler, Brenda Shafer, Marc Lussier, Chuanyun Luo, Siew Loon Ooi, Peter Philippsen, Angela M. Chu, Guido Volckaert, Rong Mao, Peter Kötter, Keith Anderson, Ching Yun Wang, Julie Wilhelmy, Ulrich Güldener, Li Ni, Lucy Y. Liu, Mark Gerstein, David C. Lamb, Steven L. Kelly, Carla Connelly, Diane E. Kelly, Svenja Hempel, Rocío Benito, David J. Garfinkel, Bruno André, Hong Liang, Sophie Brachat
Publikováno v:
Nature. 418:387-391
Determining the effect of gene deletion is a fundamental approach to understanding gene function. Conventional genetic screens exhibit biases, and genes contributing to a phenotype are often missed. We systematically constructed a nearly complete col
Autor:
Maria L. Kireeva, Brenda Schafer, Ingold Huang, Mikhail Kashlev, Deanna Gotte, Jordan D. Irvin, Jeffrey N. Strathern
Publikováno v:
The FASEB Journal. 28
Transcription errors have been proposed to contribute to tumorigenesis and neurodegenerative diseases. An experimental validation of the biological impact of transcription errors faces major challe...
Autor:
Daniel C. St. Louis, David W. Ritchey, Eric Sanders-Buell, Mika Salminen, Deanna Gotte, Jean K. Carr, Francine E. McCutchan
Publikováno v:
Journal of Virology. 72:3991-3998
Recombinant forms of human immunodeficiency virus type 1 (HIV-1) have been shown to be of major importance in the global AIDS pandemic. Viral RNA dimer formation mediated by the dimerization initiation sequence (DIS) is believed to be essential for v
Autor:
Francine E. McCutchan, Andrew W. Artenstein, Mika Salminen, Donald S. Burke, Jean K. Carr, C Koch, Patricia A. Hegerich, Deanna Gotte, D C St Louis
Publikováno v:
Scopus-Elsevier
Human immunodeficiency virus type 1 isolates of envelope genotype E are contributing substantially to the global pandemic. These strains appear to be mosaics, with the gag gene from clade A and the envelope from clade E; the parental clade E strain h