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of 4
pro vyhledávání: '"Deanna Gage"'
Autor:
Jamie Blackbourne, Dan Weinzapfel, G.Keith Matheson, Deanna Gage, Andrew Knowles, Deanne Guthrie
Publikováno v:
General Pharmacology: The Vascular System. 29:823-828
1. The effects of ipsapirone, nefazodone, tiaspirone, BMS-20661, buspirone and gepirone on the hypothalamic-pituitary-adrenal (HPA) axis were studied. These drugs were selected because they have serontonin 1A (5-HT1A) receptor-binding capability and
Autor:
Jamie Blackbourne, Deanne Guthrie, Carla Michel, Keith Matheson, Christopher Bauer, Andrew Knowles, Deanna Gage, Dan Weinzapfel
Publikováno v:
Pharmacology. 55:59-65
The effects of tandospirone, enciprazine, gepirone, buspirone (5-HT1A agents) and carvotroline (5-HT2) on hypothalamic-pituitary-adrenocortical activity (HPA) activity were studied. These drugs increased the plasma corticosterone levels in a dose-dep
Publikováno v:
Neuropharmacology. 27(8)
The effects of the anxiolytic agents, buspirone and diazepam, on the hypothalamic-pituitary-adrenal axis (HPAA), indicated by changes in the concentration of corticosterone (CS) in plasma, were studied 1 2 , 1, 2, 4, 6, 8 and 24 hr after administrati
Autor:
Deanne Guthrie, Janet Rhoades, Deanna Gage-White, Gary W. White, G.K. Matheson, Vanessa Dixon
Publikováno v:
Neuropharmacology. 28(4)
It was found that gepirone and 1-(2-pyrimidinyl)-piperazine (1-PP) increased levels of corticosterone in plasma in the intact rat. Gepirone was more potent and more efficacious than its metabolite, 1-PP. The ED50 was 6.4 μmol/kg for gepirone and 65.