Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Deanna G. Adams"'
Autor:
Marco Padilla-Rodriguez, Sara S. Parker, Deanna G. Adams, Thomas Westerling, Julieann I. Puleo, Adam W. Watson, Samantha M. Hill, Muhammad Noon, Raphael Gaudin, Jesse Aaron, Daoqin Tong, Denise J. Roe, Beatrice Knudsen, Ghassan Mouneimne
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Whilst estrogen is known to be tumorigenic in some breast cancer, in some contexts it can be protective against invasion and dissemination. Here, the authors show estrogen can promote generation of Suppressive Cortical Actin Bundles that can inhibit
Externí odkaz:
https://doaj.org/article/46283693eda645978c7dcb8a878cd28b
Autor:
Raphael Gaudin, Denise J. Roe, Ghassan Mouneimne, Deanna G. Adams, Sara S. Parker, Thomas Westerling, Samantha M. Hill, Marco Padilla-Rodriguez, Adam W. Watson, Jesse Aaron, Julieann I. Puleo, Daoqin Tong, Beatrice S. Knudsen, Muhammad S. Noon
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2018, 9 (1), ⟨10.1038/s41467-018-05367-2⟩
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Nature Communications, 2018, 9 (1), ⟨10.1038/s41467-018-05367-2⟩
Nature Communications, Nature Publishing Group, 2018, 9 (1), ⟨10.1038/s41467-018-05367-2⟩
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Nature Communications, 2018, 9 (1), ⟨10.1038/s41467-018-05367-2⟩
Estrogen promotes growth of estrogen receptor-positive (ER+) breast tumors. However, epidemiological studies examining the prognostic characteristics of breast cancer in postmenopausal women receiving hormone replacement therapy reveal a significant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31e36ae1c41a7de8002ff1dd0063f769
https://hal.archives-ouvertes.fr/hal-02338283
https://hal.archives-ouvertes.fr/hal-02338283
Autor:
Yu Wang, Michel Fink, Achim Brinker, Jason Chyba, Puiying A. Mak, Genevieve Welch, Emmanuel Claret, Jeremy S. Caldwell, Paul A. Anderson, Anthony P. Orth, Jason T. Matzen, Michael Garcia, Timothy R. Smith, Deanna G Adams, Orzala Shalizi
Publikováno v:
Current Chemical Genomics
High-throughput cellular profiling has successfully stimulated early drug discovery pipelines by facilitating targeted as well as opportunistic lead finding, hit annotation and SAR analysis. While automation-friendly universal assay formats exist to
Publikováno v:
Biochemistry. 45:10020-10029
Protein serine/threonine phosphatase 2A (PP2A) is a critical regulator of numerous cellular signaling processes and a potential target for reactive electrophiles that dysregulate phosphorylation-dependent signal transduction cascades. The predominant
Autor:
Deanna G. Adams, Steven L. Pelech, Hong Zhang, R. Lane Coffee, Brian E. Wadzinski, Stefan Strack
Publikováno v:
Journal of Biological Chemistry. 280:42644-42654
Protein serine/threonine phosphatase 2A (PP2A) regulates a wide variety of cellular signal transduction pathways. The predominant form of PP2A in cells is a heterotrimeric holoenzyme consisting of a scaffolding (A) subunit, a regulatory (B) subunit,
Publikováno v:
Archives of Biochemistry and Biophysics. 407:103-116
Much effort has focused on the identification of MAPK cascades that are activated by the MEKK family of protein kinases. However, direct phosphorylation and regulation of the MEKK proteins has not been shown. To address this question, we have express
Publikováno v:
Journal of Biological Chemistry. 277:32905-32914
Associated with the metastatic progression of epithelial tumors is the dynamic regulation of cadherins. Whereas E-cadherin is expressed in most epithelium and carcinomas, recent studies suggest that the up-regulation of other cadherin subtypes in car
Autor:
Deanna G, Adams, Brian E, Wadzinski
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 365
Protein serine/threonine phosphatase 2A (PP2A) is a major cellular enzyme implicated in the control of a wide variety of biological processes. The predominant form of PP2A in cells is a heterotrimeric holoenzyme (ABC) consisting of a scaffolding (A)
Autor:
Deanna G. Adams, Brian E. Wadzinski
Protein serine/threonine phosphatase 2A (PP2A) is a major cellular enzyme implicated in the control of a wide variety of biological processes. The predominant form of PP2A in cells is a heterotrimeric holoenzyme (ABC) consisting of a scaffolding (A)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::016c3f4586fc5ac7484c7c0cfb1ffae1
https://doi.org/10.1385/1-59745-267-x:101
https://doi.org/10.1385/1-59745-267-x:101
Autor:
Kathryn J. Brayer, Richard R. Vaillancourt, Nathaniel McCormick, Deanna G. Adams, Brian E. Wadzinski, Anne Fritz
Publikováno v:
The Journal of biological chemistry. 281(10)
MAPK/ERK kinase kinase 3 (MEKK3) is a mitogen-activated protein kinase kinase kinase (MAP3K) that functions upstream of the MAP kinases and IkappaB kinase. Phosphorylation is believed to be a critical component for MEKK3-dependent signal transduction