Výsledky vyhledávání - "Deanna Fisher"

BIOM-05. THE HER2 FLIP: HER2 AMPLIFICATION OF TUMOR CELLS IN THE CEREBROSPINAL FLUID (CSF-TCS) OF PATIENTS WITH SOLID TUMOR LEPTOMENINGEAL METASTASIS

Publikováno v: Neuro-Oncology. 24:vii4-vii5

INTRODUCTION Patients with leptomeningeal metastasis (LM) have limited treatment options and a poor outcome. However, they may benefit from targeted therapy. LM patients with HER2-positive primary breast cancer treated with IT trastuzumab demonstrate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d340727026708ee4cec3fae296a0c1ed
https://doi.org/10.1093/neuonc/noac209.015

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INNV-19. THE DETECTION OF DISSEMINATED PINEAL PARENCHYMAL TUMOR OF INTERMEDIATE DIFFERENTIATION (PPTID) IN CEREBROSPINAL FLUID (CSF) USING CELL CAPTURE AND IMMUNOCYTOCHEMISTRY

Autor: Kaitlyn Armijo, Nathan Sweed, Steven Hsiao, Tony Pircher, Mikayla Marrin, Leslie Cho, Kelly Kreitzburg, Barbara Blouw, Deanna Fisher, Michael Dugan, Santosh Kesari

Publikováno v: Neuro-Oncology. 24:vii145-vii145

BACKGROUND Pineal parenchymal tumors of intermediate differentiation (PPTID) account for 21% to 54% of pineal parenchymal tumors and may be complicated by cerebrospinal dissemination (most commonly at time of reoccurrence; up to 4-10 years post resec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3f314c85d636c61a96ec5dcf8ea10ef2
https://doi.org/10.1093/neuonc/noac209.559

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Abstract PD4-03: Characterization of HER2 amplification in the cerebrospinal fluid of patients with Leptomeningeal Disease in stage IV patients with breast cancer

Autor: Michael Dugan, Deanna Fisher, Nathan Sweed, Barbara Blouw, Julie Mayer

Publikováno v: Cancer Research. 82:PD4-03

Introduction. Breast cancers that metastasize to the central nervous system (BrM) and progress to leptomeningeal disease (LMD) are commonly HER2 amplified. Triple negative breast cancer (TNBC) also may also acquire HER2 amplification and/or copy numb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c2633aa28ce8f94443662174b02a35c2
https://doi.org/10.1158/1538-7445.sabcs21-pd4-03

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BIOM-05. CASE SERIES OF MULTI-INSTITUTIONAL UTILITY OF CNSide TO MANAGE LEPTOMENINGEAL DISEASE IN PATIENTS WITH METASTATIC BREAST CANCER

Autor: Michael Dugan, Deanna Fisher, Priya Kumthekar, Barbara Blouw, Julie Ann Mayer, Nicholas Blondin, Amir Azadi

Publikováno v: Neuro Oncol

INTRODUCTION Leptomeningeal Disease (LMD) occurs in 5% of breast cancer patients. Diagnosing LMD remains challenging. Current standard of care has limited sensitivity and is inadequate for monitoring treatment response. Biocept’s CNSide™ is a pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0a1672fe312e9ab971e61b44dd8c7fe
https://doi.org/10.1093/neuonc/noab196.036

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LMD-15. Beyond cytologY - A single institution experience using CNSideTM for diagnosing and monitoring treatment response in Non-Small Cell Lung Cancer patients with Leptomeningeal Carcinomatosis (LMC)

Autor: Sonam Puri, Julie Ann Mayer, Michael Dugan, Barbara Blouw, Wallace Akerley, Anna Weinberg Chalmers, Robbie Schultz, Deanna Fisher, Smitha Boorgula

Publikováno v: Neuro-oncology Advances

Introduction Leptomeningeal Carcinomatosis (LMC) occurs in 3–9% of Non-Small Cell Lung Cancer (NSCLC) patients. Diagnosis of LMC includes clinical evaluation, imaging, and cytology. These have modest sensitivity and are inadequate for monitoring tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adc63232833aedb179994c16ee1035e1
http://europepmc.org/articles/PMC8351243

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BIOM-08. TARGETSELECTORTM CEREBROSPINAL FLUID (CSF) CIRCULATING TUMOR CELLS AND BIOMARKER ANALYSIS: IMPROVING SENSITIVITY AND TARGETED TREATMENT OPTIONS IN BREAST AND NSCLC CANCER PATIENTS WITH CNS INVOLVEMENT

Autor: Santosh Kesari, Jose Carrillo, Lucia Dobrawa, Judy Troung, Veena M. Singh, Naveed Wagle, Robbie Schultz, Jaya Gill, Julie Ann Mayer, Deanna Fisher, Smitha Boorgula, Minhdan Nguyen

Publikováno v: Neuro Oncol

BACKGROUND Liquid biopsy has emerged as a minimally invasive and cost-effective strategy to assess cancer biomarkers without the risk of complications associated with biopsies. Once a tumor has metastasized to the brain, circulating tumor cells (CTCs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08335f2c527d963ab9587740c6fde814
https://doi.org/10.1093/neuonc/noaa215.008

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The next generation of cerebrospinal fluid (CSF)-based molecular diagnostics: Improving sensitivity and actionability in breast and lung cancer patients with CNS involvement

Autor: Jaya Gill, David Berz, Veena M. Singh, Minhdan Nguyen, Julie Ann Mayer, Deanna Fisher, Robbie Schultz, Jose Carrillo, Lucia Dobrawa, Santosh Kesari, Smitha Boorgula, Judy Troung

Publikováno v: Journal of Clinical Oncology. 38:e14502-e14502

e14502 Background: Liquid biopsy has emerged as a minimally invasive and cost-effective strategy to assess cancer biomarkers without the risk of complications associated with surgical biopsies. Once a tumor has metastasized to the brain, circulating

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7f4561feb19c2adc36f0139043df9ad1
https://doi.org/10.1200/jco.2020.38.15_suppl.e14502

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Diagnosis of leptomeningeal metastasis (LM) through identification of circulating tumor cells (CTCs) in cerebrospinal fluid (CSF)

Autor: Melissa Kate Accordino, Katherine D. Crew, Shing Mirn Lee, Teri Kreisl, Kevin Kalinsky, David Cieremans, Andrew B. Lassman, Veena M. Singh, Lan Huynh, Kathleen Fenn, Dawn L. Hershman, Meghna S. Trivedi, Fabio M. Iwamoto, Julie Ann Mayer, Deanna Fisher, Robbie Schultz, Edgar V. Sales

Publikováno v: Journal of Clinical Oncology. 38:3567-3567

3567 Background: Diagnosis of LM from solid tumors can be challenging. The TargetSelector (TS) CTC detection assay has demonstrated highly specific and sensitive CTC capture both for epithelial (CK+) and non-epithelial (CK-) subsets. The assay utiliz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5575376a81b408c708f5338aa740eb96
https://doi.org/10.1200/jco.2020.38.15_suppl.3567

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