Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Deanna D Nguyen"'
Autor:
Thomas L. Abell, Braden Kuo, Tuba Esfandyari, Nathan D. Pfeifer, Maria Grimaldi, Cecilia Renzulli, Raffaella Tacchi, Kefei Zhou, Chris N. Barnes, Deanna D. Nguyen, Linda Nguyen, Nicholas J. Talley, Richard McCallum
Publikováno v:
Neurogastroenterology & Motility. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58770802ac2ac9a35fda4bcd7efcc576
https://doi.org/10.1111/nmo.14523
https://doi.org/10.1111/nmo.14523
Autor:
Raj Bhandari, M. Teresa Pulido-Rios, David T Beattie, Reuben Sana, Brihad Abhyankar, Jonathan A. Leighton, Jacky Woo, Richard Graham, Eva Situ, Ravi Ganeshappa, Erik Sandvik, Melanie A. Kleinschek, Whitney Krey, David L. Boyle, Deanna D Nguyen, Julián Panés, William J. Sandborn, Patrick Brassil
Publikováno v:
Journal of Crohn's & Colitis
Journal of Crohn's & colitis, vol 14, iss 9
Journal of Crohn's & colitis, vol 14, iss 9
Background and Aims Oral systemic pan-Janus kinase [JAK] inhibition is effective for ulcerative colitis [UC] but is limited by toxicities. We describe preclinical to clinical translation of TD-1473—an oral gut-selective pan-JAK inhibitor—from in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e5f63ccc3b54b28cf78acb55ba9f1eb
https://doi.org/10.1093/ecco-jcc/jjaa049
https://doi.org/10.1093/ecco-jcc/jjaa049
Autor:
Maria Grimaldi, Deanna D Nguyen, Daniel Canafax, Cecilia Renzulli, David A. Shaywitz, Henry P. Parkman, Barnes Christopher Noel, Braden Kuo
Publikováno v:
Alimentary pharmacologytherapeuticsREFERENCES. 54(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a56e8849435c8d66041b4069d5f6fe65
https://pubmed.ncbi.nlm.nih.gov/34170529
https://pubmed.ncbi.nlm.nih.gov/34170529
Autor:
Silvio Danese, William J. Sandborn, Laurent Peyrin-Biroulet, Deanna D. Nguyen, Tadhg Guerin, Piotr Rozpondek, Ravi Ganeshappa, Vladyslav Dubovyi, David Bourdet, Brihad Abhyankar
Publikováno v:
Gastroenterology. 162:S-964
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ea80f00b72bf544e3b19ab1029ff813
https://doi.org/10.1016/s0016-5085(22)62285-6
https://doi.org/10.1016/s0016-5085(22)62285-6
Autor:
Atul K. Bhan, Joshua R. Korzenik, Elisa K. Boden, Francis A. Farraye, Ashwin N. Ananthakrishnan, Roopali Gandhi, Christopher J. Moran, William A Dunn, Howard L. Weiner, Deanna D. Nguyen, Vijay Yajnik, James B. Canavan, Scott B. Snapper, Katelyn McCann
Publikováno v:
Crohn's & Colitis 360
Aim The aim of this study was to determine the immunologic effects and safety of oral anti-CD3 in patients with ulcerative colitis (UC). Methods An open-label pilot study of orally delivered anti-CD3 was performed in patients with moderate-to-severe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be7f8c37546bfc4a9c6d6149054f350a
https://pubmed.ncbi.nlm.nih.gov/31423487
https://pubmed.ncbi.nlm.nih.gov/31423487
Autor:
Bobby J. Cherayil, Allan M. Goldstein, Naomi L. Ward, Yan Song, Hai Ning Shi, Richard A. Hodin, Caleb D. Phillips, Nanda Kumar N. Shanmugam, Deanna D. Nguyen
Publikováno v:
Inflammatory Bowel Diseases. 22:2328-2340
Background The interplay between host genetics, immunity, and microbiota is central to the pathogenesis of inflammatory bowel disease. Previous population-based studies suggested a link between antibiotic use and increased inflammatory bowel disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21e23ebd809fbc632f14177f2e5fe965
https://doi.org/10.1097/mib.0000000000000914
https://doi.org/10.1097/mib.0000000000000914
Autor:
Edward Shelton, Ashwin N. Ananthakrishnan, Jenny Sauk, John J. Garber, Cosmas Giallourakis, Sonia Friedman, Punyaganie de Silva, Jessica R. Allegretti, Betsy W. Stevens, Fredrick Makrauer, Matthew J. Hamilton, Jonathan S. Levine, Deanna D. Nguyen, Joshua R. Korzenik, Michal Tomczak, Hamed Khalili, Robert Burakoff, Vijay Yajnik, Matthew B. Lucci
Publikováno v:
Inflammatory Bowel Diseases. 21:2879-2885
Background Vedolizumab (VDZ) demonstrated efficacy in Crohn's disease (CD) and ulcerative colitis (UC) in the GEMINI trials. Our aim was to evaluate the efficacy of VDZ at week 14 in inflammatory bowel disease in a multicenter cohort of patients. Met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::452c13be97853a3527426178796ee0a3
https://doi.org/10.1097/mib.0000000000000561
https://doi.org/10.1097/mib.0000000000000561
Autor:
Fernanda Stephanie Santos, Ivan D. Mascanfroni, Aleixo M. Muise, J. Rodrigo Mora, Scott B. Snapper, Jeremy A. Goettel, Mouna Ibourk, Laurie S. Conklin, Christen L. Ebens, Raz Somech, Ziad Al Adham, Batia Weiss, Werner Müller, Evan Conaway, Sydney Lavoie, Naresh Singh Redhu, Johanna C. Escher, Janneke N. Samsom, Deanna D. Nguyen, Christoph Klein, Bruce H. Horwitz, Mark Sherlock, Dror S. Shouval, Francisco J. Quintana, Amlan Biswas, Alexandre Rodrigues Ferreira, Atul K. Bhan, Katelyn McCann, Rita Beier
Publikováno v:
Europe PubMed Central
Immunity, 40(5), 706-719. Cell Press
Immunity, 40(5), 706-719. Cell Press
Intact interleukin-10 receptor (IL-10R) signaling on effector and T regulatory (Treg) cells are each independently required to maintain immune tolerance. Here we show that IL-10 sensing by innate immune cells, independent of its effects on T cells, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cc4193cb1c02a5044ee38afada31a1c
https://doi.org/10.1016/j.immuni.2014.03.011
https://doi.org/10.1016/j.immuni.2014.03.011
Autor:
Vijay Yajnik, Ashwin N. Ananthakrishnan, Stephanie Cantu, Gauree G. Konijeti, Zachary A. Zator, Jenny Sauk, Deanna D. Nguyen
Publikováno v:
Journal of Parenteral and Enteral Nutrition. 38:385-391
Introduction: Emerging evidence supports an immunologic role for 25-hydroxyvitamin D (25(OH)D) in inflammatory bowel disease (IBD). Here we examined if pretreatment vitamin D status influences durability of anti–tumor necrosis factor (TNF)–α the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1210f26070aa3e7c78248d04cb711251
https://doi.org/10.1177/0148607113504002
https://doi.org/10.1177/0148607113504002
Autor:
Suresh Muthupalani, Jeremy A. Goettel, Nancy S. Taylor, Romela Marin, Deanna D. Nguyen, James G. Fox, Melissa W. Mobley, Amanda McCabe, Michelle A. Eston, Scott B. Snapper
Publikováno v:
PMC
Background: Wiskott–Aldrich syndrome protein–deficient patients and mice are immunodeficient and can develop inflammatory bowel disease. The intestinal microbiome is critical to the development of colitis in most animal models, in which Helicobac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f913a3ed3370392de10c2dfaef2db0a8
https://doi.org/10.1097/mib.0b013e318295fd8f
https://doi.org/10.1097/mib.0b013e318295fd8f