Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Deanna, Montgomery"'
Autor:
Traynor, Deanna Montgomery, Hartman Jg, Henry I. Mosberg, Sánchez-Santiago Aa, Nicholas W. Griggs, Jessica P. Anand, Thomas J Fernandez, Irina D. Pogozheva
Publikováno v:
ACS Chemical Neuroscience. 10:3682-3689
The dimethyltyrosine–tetrahydroisoquinoline (Dmt-Tiq) scaffold was originally developed in the production of selective delta opioid receptor (DOR) antagonists. Installation of a 7-benzyl pendant on...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::179acd152579ad14ee6a988ea61d1c51
https://doi.org/10.1021/acschemneuro.9b00250
https://doi.org/10.1021/acschemneuro.9b00250
Autor:
Aaron M. Bender, Thomas J Fernandez, John R. Traynor, Emily M. Jutkiewicz, Henry I. Mosberg, Nicholas W. Griggs, Jessica P. Anand, Anthony F. Nastase, Deanna Montgomery
Publikováno v:
Journal of Medicinal Chemistry. 62:4193-4203
Short-acting μ-opioid receptor (MOR) agonists have long been used for the treatment of severe, breakthrough pain. However, selective MOR agonists including fentanyl and morphine derivatives are limited clinically due to high risks of dependence, tol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbfc327b5a0e52c3aca3e632834c3510
https://doi.org/10.1021/acs.jmedchem.9b00378
https://doi.org/10.1021/acs.jmedchem.9b00378
Autor:
Deanna Montgomery
Publikováno v:
Nature
Deanna Montgomery realizes she doesn’t need to be at a laboratory bench to use her scientific experience — or to make a difference. Deanna Montgomery realizes she doesn’t need to be at a laboratory bench to use her scientific experience — or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bff1b6071ece85e1f146fdb6ba71f761
Autor:
Emily M. Jutkiewicz, Nicholas W. Griggs, Henry I. Mosberg, Jessica P. Anand, Anthony F. Nastase, Deanna Montgomery, Kelsey E Kochan, John R. Traynor
Publikováno v:
British Journal of Pharmacology. 175:2013-2027
BACKGROUND AND PURPOSE Agonists at μ-opioid receptors (μ-receptors) are used for pain management but produce adverse effects including tolerance, dependence and euphoria. The co-administration of a μ-receptor agonist with a δ-opioid receptor (δ-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5ca42222ac9170fc7afdba2255cc86f
https://doi.org/10.1111/bph.14148
https://doi.org/10.1111/bph.14148
Autor:
Delong Lj, Hartman Jg, Traynor, Jessica P. Anand, Deanna Montgomery, Baber Ma, Jack. J. Twarozynski, Henry I. Mosberg
Publikováno v:
Molecules
Volume 24
Issue 23
Volume 24
Issue 23
The opioid receptors modulate a variety of biological functions, including pain, mood, and reward. As a result, opioid ligands are being explored as potential therapeutics for a variety of indications. Multifunctional opioid ligands, which act simult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b15f94804488409c30a270f96184f43
Autor:
Jessica P, Anand, Deanna, Montgomery
Publikováno v:
Handbook of experimental pharmacology. 247
The opioid receptor system plays a major role in the regulation of mood, reward, and pain. The opioid receptors therefore make attractive targets for the treatment of many different conditions, including pain, depression, and addiction. However, stim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f910ec2ff8b3f168889a24deeb27f300
https://pubmed.ncbi.nlm.nih.gov/29675582
https://pubmed.ncbi.nlm.nih.gov/29675582
Autor:
Jessica P. Anand, Deanna Montgomery
Publikováno v:
Delta Opioid Receptor Pharmacology and Therapeutic Applications ISBN: 9783319951317
The opioid receptor system plays a major role in the regulation of mood, reward, and pain. The opioid receptors therefore make attractive targets for the treatment of many different conditions, including pain, depression, and addiction. However, stim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bfe7a5b077ea1f7bc17805e9acf1f90
https://doi.org/10.1007/164_2018_104
https://doi.org/10.1007/164_2018_104
Autor:
Jessica P, Anand, Kelsey E, Kochan, Anthony F, Nastase, Deanna, Montgomery, Nicholas W, Griggs, John R, Traynor, Henry I, Mosberg, Emily M, Jutkiewicz
Publikováno v:
British journal of pharmacology. 175(11)
BACKGROUND AND PURPOSE: Agonists at μ‐opioid receptors (μ‐receptors) are used for pain management but produce adverse effects including tolerance, dependence and euphoria. The co‐administration of a μ‐receptor agonist with a δ‐opioid re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::28125a02c42cbdd344b119d69c09dd46
https://pubmed.ncbi.nlm.nih.gov/29352503
https://pubmed.ncbi.nlm.nih.gov/29352503
Autor:
Choong L. Yoo, Baoxue Yang, Brandi M. Hudson, Mark J. Kurth, Gui J. Yu, Huy Nguyen, Dean J. Tantillo, Alan S. Verkman, Michael W. Lodewyk, Puay Wah Phuan, Deanna Montgomery, Alex L. Bagdasarian, Keith C. Coffman
Publikováno v:
Journal of Medicinal Chemistry
Conformationally constrained bithiazoles were previously found to have improved efficacy over nonconstrained bithiazoles for correction of defective cellular processing of the ΔF508 mutant cystic fibrosis transmembrane conductance regulator (CFTR) p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e41d6e8404d5899fdc52c2ea8d8d05ff
https://doi.org/10.1021/jm5007885
https://doi.org/10.1021/jm5007885
Publikováno v:
Journal of the American Dietetic Association. 95:644-646
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b63fb9cac0ffc0e0612308cff564392f
https://doi.org/10.1016/s0002-8223(95)00174-3
https://doi.org/10.1016/s0002-8223(95)00174-3