Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Dean-Paulos Klötzner"'
Autor:
Christina Helmling, Dean-Paulos Klötzner, Florian Sochor, Rachel Anne Mooney, Anna Wacker, Robert Landick, Boris Fürtig, Alexander Heckel, Harald Schwalbe
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Riboswitches are RNA-based regulatory elements, which regulate downstream gene expression by binding of small molecular weight ligands. Here the authors demonstrate the molecular mechanism of a transcriptional riboswitch that integrates changes in tr
Externí odkaz:
https://doaj.org/article/cba69ad002cb4eff9de91d0845331311
Autor:
Eva Marie Oberhauser, Heidi Zetzsche, Harald Schwalbe, Dean-Paulos Klötzner, Alexander Heckel, Boris Fürtig
Publikováno v:
Biochemistry. 59(10)
The adenine-sensing riboswitch from the gram-negative bacterium V. vulnificus is an RNA-based gene regulatory element that acts both in response to its cognate low molecular weight ligand and to te...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32fd4cd0d863caec7559eb8926ac73bf
https://pubmed.ncbi.nlm.nih.gov/32134253
https://pubmed.ncbi.nlm.nih.gov/32134253
Autor:
Robert W. Harkness, Irene Bessi, Dean-Paulos Klötzner, Harald Schwalbe, Christopher D Hennecker, Alexander Heckel, J Tassilo Grün, Anthony Mittermaier
Publikováno v:
Journal of the American Chemical Society. 142(1)
The complex folding energy landscape of DNA G-quadruplexes leads to numerous conformations for this functionally important class of noncanonical DNA structures. A new layer of conformational heterogeneity comes from sequences with different numbers o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62cf07cb7d333cab1e503a3b32f30a12
https://pubmed.ncbi.nlm.nih.gov/31815451
https://pubmed.ncbi.nlm.nih.gov/31815451
Publikováno v:
Chemical Communications. 53:9874-9877
A new photoactivatable fluorophore based on a quinone-cyanine-7 (QCy7) scaffold was synthesized and spectroscopically characterized. The fluorophore exhibits fluorescence in the near-infrared spectral window and a large Stokes shift. Its application
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7af396fd52eadad43e0089e66872247
https://doi.org/10.1039/c7cc04996j
https://doi.org/10.1039/c7cc04996j
Autor:
Florian Sochor, Rachel A. Mooney, Dean-Paulos Klötzner, Harald Schwalbe, Alexander Heckel, Christina Helmling, Robert Landick, Boris Fürtig, Anna Wacker
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Transcriptional riboswitches modulate downstream gene expression by a tight coupling of ligand-dependent RNA folding kinetics with the rate of transcription. RNA folding pathways leading to functional ON and OFF regulation involve the formation of me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b77f74dfbbd2c6b5a70cc72f7d9d8f57
http://europepmc.org/articles/PMC5838219
http://europepmc.org/articles/PMC5838219
Autor:
Patrick Seyfried, Michael Bolte, Alexander Heckel, Gerhard Hummer, Marcel Heinz, György Pintér, Yvonne Becker, Harald Schwalbe, Hendrik R. A. Jonker, Lukas S. Stelzl, Dean-Paulos Klötzner
Publikováno v:
Chemistry-A European Journal
Photolabile protecting groups are widely used to trigger oligonucleotide activity. The ON/OFF‐amplitude is a critical parameter. An experimental setup has been developed to identify protecting group derivatives with superior caging properties. Bulk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1789fa43b9af9f3ef2ce97a04eb3c56a