Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Dean W. Roberts"'
Publikováno v:
Journal of oleo science. 69(11)
According to CODEX, moisture and volatile matter are olive oil quality parameters and the development of a rapid screening method for the determination of moisture is of interest. We recently demonstrated for the first time that the weak near-infrare
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f5c63225e008e3f29d7f0f15dba0a96
https://pubmed.ncbi.nlm.nih.gov/33055436
https://pubmed.ncbi.nlm.nih.gov/33055436
Acetaminophen liver injury is the most common cause of acute liver injury in the United States and several other countries. Diagnosis of acetaminophen-induced acute liver injury in the clinic is challenging due to the lack of validated and specific b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe74958c47fa5526db7cb3e61df5a536
https://doi.org/10.1016/bs.acc.2020.02.002
https://doi.org/10.1016/bs.acc.2020.02.002
Autor:
Jason D. Holton, Jianwei Qin, Andrew Mackey, Peter F. Scholl, Jeffrey C. Moore, Joseph H. LaPointe, Dean W. Roberts, Gerard Downey, Steven Zbylut, Moon S. Kim, Stephen E. Holroyd, Greg A. Israelson, Kuanglin Chao, William J. Hurst, Anitra Payne, Magdi M. Mossoba, Marti Mamula Bergana, Carol Zrybko, Zhuohong Xie, Martin Buehler, Robert L. Magaletta, Joseph E. Jablonski, Betsy Jean Yakes
Publikováno v:
Journal of Agricultural and Food Chemistry. 65:5799-5809
The United States Pharmacopeial Convention has led an international collaborative project to develop a toolbox of screening methods and reference standards for the detection of milk powder adulteration. During the development of adulterated milk powd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::370eadb6bf84f45417b600f646f19e3a
https://doi.org/10.1021/acs.jafc.7b02083
https://doi.org/10.1021/acs.jafc.7b02083
Autor:
Richard C. Kurten, Cynthia J. Koziol-White, Hartmut Jaeschke, Katherine Caid, Stacie M. Jones, Pritmohinder S. Gill, Laura P. James, Reynold A. Panettieri, Mitchell R. McGill, Dean W. Roberts, Joshua L. Kennedy, Sandra S. McCullough
Publikováno v:
Xenobiotica
Epidemiologic studies have demonstrated an association between acetaminophen (APAP) use and the development of asthma symptoms. However, few studies have examined relationships between APAP-induced signaling pathways associated with the development o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03269d257f8a8fa01b894a82804cc6c0
Autor:
Jack A. Hinson, Shasha Bai, Lynda Letzig, Daniel Ganger, Jody Rule, R. Todd Stravitz, Adrian Reuben, Robert J. Fontana, Christopher J. Swearingen, Oren K. Fix, Dean W. Roberts, Laura P. James, William M. Lee, Iris Liou, K. Rajender Reddy, Pippa Simpson
Publikováno v:
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 15(4)
A rapid and reliable point-of-care assay to detect acetaminophen protein adducts in the serum of patients with acute liver injury could improve diagnosis and management. AcetaSTAT is a competitive immunoassay used to measure acetaminophen protein add
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::698c07c839e0317adf800aac80b5c757
https://pubmed.ncbi.nlm.nih.gov/28017841
https://pubmed.ncbi.nlm.nih.gov/28017841
Autor:
Dean W. Roberts, Xi Yang, Qiang Shi, Levan Muskhelishvili, William F. Salminen, Kelly Davis, James Greenhaw, Jack A. Hinson
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 344:286-294
Acetaminophen (APAP)-induced liver injury is the leading cause of acute liver failure in many countries. This study determined the extent of liver protein sulfhydryl depletion not only in whole liver homogenate but also in the zonal pattern of sulfhy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f4e4e1085a79691eafb21be01d4fff9
https://doi.org/10.1124/jpet.112.199067
https://doi.org/10.1124/jpet.112.199067
Autor:
Dean W. Roberts, Xinxin Ding, Fang Xie, Kerri Kluetzman, Robert C. Karn, Qing Yu Zhang, Christina M. Laukaitis, Jun Gu, Xin Zhou, Yuan Wei
Publikováno v:
Molecular Pharmacology. 79:710-723
To identify novel factors or mechanisms that are important for the resistance of tissues to chemical toxicity, we have determined the mechanisms underlying the previously observed increases in resistance to acetaminophen (APAP) toxicity in the latera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ca0cfaee9bbd400c78a1c346a74c74f
https://doi.org/10.1124/mol.110.070045
https://doi.org/10.1124/mol.110.070045
Autor:
Laura James, Dean W. Roberts
Publikováno v:
Hepatology. 59:746-748
The report by Metushi et al. “Detection of Anti-Isoniazid and Anti-CYP Antibodies in Patients with Isoniazid-Induced Liver Failure” addresses the role of the immune response in isoniazid (INH) mediated liver injury. Isoniazid is an essential drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba72c607fc8fc9afe66883182c3d7974
https://doi.org/10.1002/hep.26707
https://doi.org/10.1002/hep.26707
Autor:
William W. Yu, Nigel J. Walker, Christy R. Cozart, Dean W. Roberts, Vicki L. Colvin, Peggy J. Webb, Paul C. Howard, Alan R. Warbitton, Neera V. Gopee, Paul H. Siitonen, John R. Latendresse
Publikováno v:
Toxicological Sciences. 111:37-48
Many cosmetics, sunscreens, and other consumer products are reported to contain nanoscale materials. The possible transdermal absorption of nanoscale materials and the long-term consequences of the absorption have not been determined. We used polyeth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8d7aa772a78a1c4bd8b83a63f5baea6
https://doi.org/10.1093/toxsci/kfp139
https://doi.org/10.1093/toxsci/kfp139
Autor:
Laura P. James, Dean W. Roberts, Jack A. Hinson, William M. Lee, Lynda Letzig, Timothy J. Davern, Edmund V. Capparelli, Pippa Simpson
Publikováno v:
Drug Metabolism and Disposition. 37:1779-1784
Acetaminophen (APAP)-induced liver toxicity occurs with formation of APAP-protein adducts. These adducts are formed by hepatic metabolism of APAP to N-acetyl-p-benzoquinone imine, which covalently binds to hepatic proteins as 3-(cystein-S-yl)-APAP ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a7f2d8e93ed2db4deae18e6d462233c
https://doi.org/10.1124/dmd.108.026195
https://doi.org/10.1124/dmd.108.026195