Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Dean Tan"'
Autor:
Bhoomika Sukhadia, MD, Dean Tan, BA, BS, Youjin Oh, MD, Zunairah Shah, MD, Young Kwang Chae, MD, MPH, MBA
Publikováno v:
JTO Clinical and Research Reports, Vol 5, Iss 10, Pp 100520- (2024)
IDH2 gain-of-function mutations cause DNA hypermethylation interfering with cellular differentiation and are linked to poor disease outcomes in NSCLC. IDH2-inhibitor enasidenib is approved for refractory acute myeloid leukemia but has been associated
Externí odkaz:
https://doaj.org/article/19831a8ca6a14d10bc58dd48f0004a12
Autor:
Diana Saleiro, Jeremy Q. Wen, Ewa M. Kosciuczuk, Frank Eckerdt, Elspeth M. Beauchamp, Chidera V. Oku, Gavin T. Blyth, Mariafausta Fischietti, Liliana Ilut, Marco Colamonici, William Palivos, Paula A. Atsaves, Dean Tan, Masha Kocherginsky, Rona Singer Weinberg, Eleanor N. Fish, John D. Crispino, Ronald Hoffman, Leonidas C. Platanias
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Interferon alpha (IFNalpha) therapy is showing promising results to treat myeloproliferative neoplasms (MPNs). Here, the authors show that IFNalpha response requires ULK1 phosphorylation to induce p38-MAPK signalling but it is counteracted by ROCK1-2
Externí odkaz:
https://doaj.org/article/3a0f1e5129e84efda5acd4754ca85e1b
Autor:
Dongyup Lee, Jonghanne Park, Horyun Choi, Gahyun Gim, Sukjoo Cho, Leeseul Kim, Youjin Oh, Cyra Y. Kang, Yeseul Kim, Dean Tan, Pedro Antonio Hermida de Viveiros, Young Kwang Chae
Publikováno v:
Heliyon, Vol 7, Iss 9, Pp e07916- (2021)
Background: Homozygosity at HLA-I locus has been reported to be an unfavorable predictive biomarker of second-line or beyond immunotherapy in patients with different types of cancer. The linkage between HLA-I zygosity and survival in NSCLC patients t
Externí odkaz:
https://doaj.org/article/0bf48c1f89134f10bea575e661646a58
Autor:
Pedro Viveiros, Horyun Choi, Dean Tan, Sukjoo Cho, Leeseul Kim, Gahyun Gim, Youjin Oh, Jonghanne Park, Cyra Y. Kang, Dongyup Lee, Young Kwang Chae, Yeseul Kim
BackgroundHomozygosity at HLA-I locus has been reported to be an unfavorable predictive biomarker of second-line or beyond immunotherapy in patients with different types of cancer. The linkage between HLA-I zygosity and survival in NSCLC patients tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cb571eb3489f016dfe96226d697d40d
https://doi.org/10.1101/2021.05.10.21256924
https://doi.org/10.1101/2021.05.10.21256924
Autor:
Heiko Enderling, Slav Yartsev, Renee Brady, Dean Tan, Enakshi D. Sunassee, Eduardo G. Moros, Tianlin Ji, Jimmy J. Caudell
Publikováno v:
Int J Radiat Biol
PurposeRadiotherapy prescription dose and dose fractionation protocols vary little between individual patients having the same tumor grade and stage. To personalize radiotherapy a predictive model is needed to simulate radiation response. Previous mo
Autor:
Jonghanne Park, Young Kwang Chae, Sukjoo Cho, Dongyup Lee, Gahyun Gim, Dean Tan, Pedro Viveiros, Cyra Y. Kang, Horyun Choi, Yeseul Kim, Youjin Oh, Leeseul Kim
Publikováno v:
Heliyon, Vol 7, Iss 9, Pp e07916-(2021)
Background Homozygosity at HLA-I locus has been reported to be an unfavorable predictive biomarker of second-line or beyond immunotherapy in patients with different types of cancer. The linkage between HLA-I zygosity and survival in NSCLC patients tr
Publikováno v:
Studying Hong Kong
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e64ee8d330ba7c1b14a3ceb16491eef
https://doi.org/10.1142/9789813223554_0016
https://doi.org/10.1142/9789813223554_0016
Autor:
Wah Kheng Dean Tan
What drives economically buoyant Southeast Asian nations, enjoying postCold War peace, to procure arms in a manner that has observers concerned about a regional arms race? Are these acquisitions driven by threats from within the region or from potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::031d9ed57c619afa9452196f52dc15e5
https://doi.org/10.21236/ad1009297
https://doi.org/10.21236/ad1009297
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-11 (2019)
Abstract Background Treatments for autoimmune diseases aim to dampen autoreactivity while preserving normal immune function. In CD4+ T cells, the transcription factor Oct1/Pou2f1 is a dispensable transcription factor for T cell development and respon
Externí odkaz:
https://doaj.org/article/9a1f504f63dc4785b017ff8231c74964
Autor:
Karina Vázquez-Arreguín, Claire Bensard, John C Schell, Eric Swanson, Xinjian Chen, Jared Rutter, Dean Tantin
Publikováno v:
PLoS Genetics, Vol 15, Iss 5, p e1007687 (2019)
The transcription factor Oct1/Pou2f1 promotes poised gene expression states, mitotic stability, glycolytic metabolism and other characteristics of stem cell potency. To determine the effect of Oct1 loss on stem cell maintenance and malignancy, we del
Externí odkaz:
https://doaj.org/article/16666d1fc9f34cec854d9be1d8d14776