Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Dean S. Dawson"'
Autor:
Susannah Rankin, Dean S. Dawson
Publikováno v:
F1000Research, Vol 5 (2016)
Sister chromatids are tethered together from the time they are formed in S-phase until they separate at anaphase. A protein complex called cohesin is responsible for holding the sister chromatids together and serves important roles in chromosome cond
Externí odkaz:
https://doaj.org/article/9f99d85391cc426782e5f04b39dfdb27
Publikováno v:
PLoS Genetics, Vol 14, Iss 8, p e1007513 (2018)
In meiosis I, homologous chromosomes segregate away from each other-the first of two rounds of chromosome segregation that allow the formation of haploid gametes. In prophase I, homologous partners become joined along their length by the synaptonemal
Externí odkaz:
https://doaj.org/article/23b96242e8ef49c8b731bb67a127e21d
Autor:
Régis E Meyer, Ashlea Sartin, Madeline Gish, Jillian Harsha, Emily Wilkie, Dawson Haworth, Rebecca LaVictoire, Isabel Alberola, Hoa H Chuong, Gary J Gorbsky, Dean S Dawson
Publikováno v:
bioRxiv
Tumor cell lines with elevated chromosome numbers frequently have correlated elevations of Mps1 expression and these tumors are more dependent on Mps1 activity for their survival than control cell lines. Mps1 is a conserved kinase involved in control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5566054b2ecec9c2132f77b7952ff4b
https://doi.org/10.1101/2023.01.09.523325
https://doi.org/10.1101/2023.01.09.523325
Proper chromosome segregation in meiosis I relies on the formation of connections between homologous chromosomes. Crossovers between homologs provide a connection that allows them to attach correctly to the meiosis I spindle. Tension is transmitted a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1b1637c347ee78a960d7e7678921fad
https://doi.org/10.1101/2022.12.19.520819
https://doi.org/10.1101/2022.12.19.520819
Publikováno v:
Molecular Biology of the Cell
In prophase of meiosis I, homologous chromosomes pair and become connected by cross-overs. Chiasmata, the connections formed by cross-overs, enable the chromosome pair, called a bivalent, to attach as a single unit to the spindle. When the meiotic sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e3428d2ab37d772453fad9d91a08833
http://europepmc.org/articles/PMC8101486
http://europepmc.org/articles/PMC8101486
Publikováno v:
Biochemistry
Condensins play a key role in higher order chromosome organization. In budding yeast Saccharomyces cerevisiae, a condensin complex consists of five subunits: two conserved structural maintenance of chromosome subunits, Smc2 and Smc4, a kleisin Brn1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::771edb63d1d66c07dd58d343a1306ea3
https://europepmc.org/articles/PMC8668321/
https://europepmc.org/articles/PMC8668321/
Publikováno v:
Chromosoma
In meiosis, crossovers between homologous chromosomes link them together. This enables them to attach to microtubules of the meiotic spindle as a unit, such that the homologs will be pulled away from one another at anaphase I. Homologous pairs can so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c367bf511482b654cedda24fa35dbcc
https://doi.org/10.1007/s00412-019-00708-6
https://doi.org/10.1007/s00412-019-00708-6
In prophase of meiosis I, homologous partner chromosomes pair and become connected by crossovers. Chiasmata, the connections formed between the partners enable the chromosome pair, called a bivalent, to attach as a single unit to the spindle. When th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15b044456d1421f7d5b8b758af50332b
https://doi.org/10.1101/2020.06.28.176370
https://doi.org/10.1101/2020.06.28.176370
Autor:
C Gaston Bisig, Michel F Guiraldelli, Anna Kouznetsova, Harry Scherthan, Christer Höög, Dean S Dawson, Roberto J Pezza
Publikováno v:
PLoS Genetics, Vol 8, Iss 6, p e1002701 (2012)
Recent studies in simple model organisms have shown that centromere pairing is important for ensuring high-fidelity meiotic chromosome segregation. However, this process and the mechanisms regulating it in higher eukaryotes are unknown. Here we prese
Externí odkaz:
https://doaj.org/article/1455676f6b4e411f96f7ea910203b6c0
Publikováno v:
Molecular Biology of the Cell. 29:479-489
In budding yeast meiosis, homologous chromosomes become linked by chiasmata and then move back and forth on the spindle until they are bioriented, with the kinetochores of the partners attached to microtubules from opposite spindle poles. Certain mut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4faffe8574f6e0d76282df765a0f2b92
https://doi.org/10.1091/mbc.e17-08-0503
https://doi.org/10.1091/mbc.e17-08-0503