Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Dean S. Carson"'
Publikováno v:
Comprehensive Psychoneuroendocrinology, Vol 11, Iss , Pp 100143- (2022)
Prenatal exposure to drugs of abuse results in neonatal abstinence syndrome (NAS). NAS causes significant morbidity and is associated with costly and lengthy hospitalization. Current pharmacotherapy is suboptimal with no FDA approved treatments. We e
Externí odkaz:
https://doaj.org/article/fb1e39e314c44667a88275c541c954fe
Autor:
David C. Yeomans, Leah R. Hanson, Dean S. Carson, Brendan J. Tunstall, Mary R. Lee, Alexander Z. Tzabazis, Daniel Jacobs, William H. Frey
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract There is evidence of the therapeutic potential of intranasal oxytocin for the treatment of pain and various psychiatric disorders, however, there is scant evidence that oxytocin reaches the brain. We quantified the concentration and distribu
Externí odkaz:
https://doaj.org/article/941b748b10d24d72a4c41802e25eb95e
Publikováno v:
The FASEB Journal. 35
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27237 (2011)
Previous studies have suggested that administration of oxytocin (OT) can have modulatory effects on social and anxiety-like behavior in mammals that may endure beyond the time of acute OT administration. The current study examined whether repeated ad
Externí odkaz:
https://doaj.org/article/688e9bea44914497910f03a59cca10cd
Intranasal oxytocin treatment for social deficits and biomarkers of response in children with autism
Autor:
Robin A. Libove, Kyle Hinman, Ozge Oztan, Antonio Y. Hardan, Joseph P. Garner, Karen J. Parker, Jennifer M. Phillips, Dean S. Carson, Raena D. Sumiyoshi, Lisa Jackson, Jacqueline E. Summers, Debra S. Karhson, Kara S. Motonaga
Publikováno v:
Proceedings of the National Academy of Sciences. 114:8119-8124
Autism spectrum disorder (ASD) is characterized by core social deficits. Prognosis is poor, in part, because existing medications target only associated ASD features. Emerging evidence suggests that the neuropeptide oxytocin (OXT) may be a blood-base
Autor:
Kara S. Motonaga, Robin A. Libove, Debra S. Karhson, Karen J. Parker, Jacqueline E. Summers, Noreen Mohsin, Lawrence K. Fung, Joseph P. Garner, Kyle Hinman, Jennifer M. Phillips, Ozge Oztan, Dean S. Carson, Antonio Y. Hardan, Raena D. Sumiyoshi
Publikováno v:
Science Translational Medicine. 11
The social impairments of autism spectrum disorder (ASD) have a major impact on quality of life, yet there are no medications that effectively treat these core social behavior deficits. Preclinical research suggests that arginine vasopressin (AVP), a
Autor:
Karen J. Parker, Jennifer M. Phillips, Raena D. Sumiyoshi, Antonio Y. Hardan, Sophie M. Rose, Lisa Jackson, Robin A. Libove, Dean S. Carson, Joseph P. Garner, Ozge Oztan, M. Mariscal, Tara H. Trujillo
Publikováno v:
Autism Res
Research suggests that children with autism spectrum disorder (ASD) may have reduced empathy, as measured by an impaired contagious yawn response, compared to typically developing (TD) children. Other research has failed to replicate this finding, in
Autor:
William H. Frey, Dean S. Carson, Jason M. Cuellar, Neil A. Manering, Daniel I. Jacobs, Michael Klukinov, Martin S. Angst, Yanli Qiao, Alexander Tzabazis, Allon Jacobs, James E. Miller, Conrado Pascual, Jordan Mechanic, David C. Yeomans
Publikováno v:
Cephalalgia. 36:943-950
Aims Our studies investigated the location of oxytocin receptors in the peripheral trigeminal sensory system and determined their role in trigeminal pain. Methods Oxytocin receptor expression and co-localization with calcitonin gene-related peptide w
Autor:
Daniel Fulford, Christopher S. Stauffer, Peter A. Arcuni, Sophia Vinogradov, Josh Woolley, Steve Batki, Dean S. Carson
Publikováno v:
Psychopharmacology (Berl)
RATIONALE: There has been an explosion of research on the potential benefits of the social neuropeptide oxytocin for a number of mental disorders including substance use disorders. Recent evidence suggests that intranasal oxytocin has both direct ant
Autor:
Matthew C. Strehlow, Dean S. Carson, Samuel H. Cheshier, Shellie A. Hyde, Joseph P. Garner, T H Trujillo, J K Moss, Antonio Y. Hardan, Karen J. Parker, Sonia Partap, Lisa Jackson, Sean Berquist, S L Hannah, Raena D. Sumiyoshi
Publikováno v:
Molecular Psychiatry. 20:1085-1090
The neuropeptide oxytocin (OXT) exerts anxiolytic and prosocial effects in the central nervous system of rodents. A number of recent studies have attempted to translate these findings by investigating the relationships between peripheral (e.g., blood