Zobrazeno 1 - 10
of 944
pro vyhledávání: '"Dean P. Jones"'
Autor:
Shabatun J. Islam, Chang Liu, Appesh N. Mohandas, Kimberly Rooney, Aditi Nayak, Anurag Mehta, Yi-An Ko, Jeong Hwan Kim, Yan V. Sun, Sandra B. Dunbar, Tené T. Lewis, Herman A. Taylor, Karan Uppal, Dean P. Jones, Arshed A. Quyyumi, Charles D. Searles
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Plasma metabolomics profiling is an emerging methodology to identify metabolic pathways underlying cardiovascular health (CVH). The objective of this study was to define metabolomic profiles underlying CVH in a cohort of Black adults, a popu
Externí odkaz:
https://doaj.org/article/9d997d7e6b21456babd9d95fccc5b720
Autor:
Kimberly C. Paul, Keren Zhang, Douglas I. Walker, Janet Sinsheimer, Yu Yu, Cynthia Kusters, Irish Del Rosario, Aline Duarte Folle, Adrienne M. Keener, Jeff Bronstein, Dean P. Jones, Beate Ritz
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-16 (2023)
Abstract Background Untargeted high-resolution metabolomic profiling provides simultaneous measurement of thousands of metabolites. Metabolic networks based on these data can help uncover disease-related perturbations across interconnected pathways.
Externí odkaz:
https://doaj.org/article/07fbe5d008ab4d408381b53a0bc4dd5d
Autor:
Dong Li, Lawrence C. Armand, Fangxu Sun, Hyun Hwang, David Wolfson, Antonio Rampoldi, Rui Liu, Parvin Forghani, Xin Hu, Wen-Mei Yu, Cheng-Kui Qu, Dean P. Jones, Ronghu Wu, Hee Cheol Cho, Joshua T. Maxwell, Chunhui Xu
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-24 (2023)
Abstract Background Cardiac pathological outcome of metabolic remodeling is difficult to model using cardiomyocytes derived from human-induced pluripotent stem cells (hiPSC-CMs) due to low metabolic maturation. Methods hiPSC-CM spheres were treated w
Externí odkaz:
https://doaj.org/article/562803dacdbb45ed92a888443f4bfd75
Autor:
Jiawen Carmen Chen, Jesse A. Goodrich, Douglas I. Walker, Jiawen Liao, Elizabeth Costello, Tanya L. Alderete, Damaskini Valvi, Hailey Hampson, Shiwen Li, Brittney O. Baumert, Sarah Rock, Dean P. Jones, Sandrah P. Eckel, Rob McConnell, Frank D. Gilliland, Max T. Aung, David V. Conti, Zhanghua Chen, Lida Chatzi
Publikováno v:
Environment International, Vol 186, Iss , Pp 108601- (2024)
Background: Strong epidemiological evidence shows positive associations between exposure to per- and polyfluoroalkyl substances (PFAS) and adverse cardiometabolic outcomes (e.g., diabetes, hypertension, and dyslipidemia). However, the underlying card
Externí odkaz:
https://doaj.org/article/a0147c01874e4d069f91ff4b60afddfd
Autor:
Hailey E. Hampson, Elizabeth Costello, Douglas I. Walker, Hongxu Wang, Brittney O. Baumert, Damaskini Valvi, Sarah Rock, Dean P. Jones, Michael I. Goran, Frank D. Gilliland, David V. Conti, Tanya L. Alderete, Zhanghua Chen, Leda Chatzi, Jesse A. Goodrich
Publikováno v:
Environment International, Vol 185, Iss , Pp 108454- (2024)
Background: Per- and polyfluoroalkyl substances (PFAS) are pollutants linked to adverse health effects. Diet is an important source of PFAS exposure, yet it is unknown how diet impacts longitudinal PFAS levels. Objective: To determine if dietary inta
Externí odkaz:
https://doaj.org/article/c26e6720f26d44f9b35eb82bfc03f6a9
Autor:
Zachery R. Jarrell, Ken H. Liu, Kristine K. Dennis, Xin Hu, Greg S. Martin, Dean P. Jones, Young‐Mi Go
Publikováno v:
FASEB BioAdvances, Vol 5, Iss 9, Pp 367-375 (2023)
Abstract This report identifies, for the first time, a phytochelatin compound, phytochelatin 2 [γ‐E‐C‐γ‐E‐C‐G], and related metabolites in human urine. Phytochelatins are metal‐binding peptides produced by plants. They are present in
Externí odkaz:
https://doaj.org/article/25583d44d3b34d91871d900b2accaf87
Autor:
Kaitlin R. Taibl, Anne L. Dunlop, Dana Boyd Barr, Yuan-Yuan Li, Stephanie M. Eick, Kurunthachalam Kannan, P. Barry Ryan, Madison Schroder, Blake Rushing, Timothy Fennell, Che-Jung Chang, Youran Tan, Carmen J. Marsit, Dean P. Jones, Donghai Liang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Marginalized populations experience disproportionate rates of preterm birth and early term birth. Exposure to per- and polyfluoroalkyl substances (PFAS) has been reported to reduce length of gestation, but the underlying mechanisms are unkno
Externí odkaz:
https://doaj.org/article/840182d125714060b347e19f2befe1ec
Autor:
Qi Yan, Di He, Douglas I. Walker, Karan Uppal, Xuexia Wang, Helen T. Orimoloye, Dean P. Jones, Beate R. Ritz, Julia E. Heck
Publikováno v:
EJC Paediatric Oncology, Vol 2, Iss , Pp 100123- (2023)
Background: Retinoblastoma is rare but nevertheless the most common pediatric eye cancer that occurs in children under age 5. High-resolution metabolomics (HRM) is a powerful analytical approach to profile metabolic features and pathways or identify
Externí odkaz:
https://doaj.org/article/2a0c8f04ca524389ac0369a6205dc85b
Autor:
Maria Saliba, Noelle Drapeau, Michelle Skime, Xin Hu, Carolyn Jonas Accardi, Arjun P. Athreya, Jacek Kolacz, Julia Shekunov, Dean P. Jones, Paul E. Croarkin, Magdalena Romanowicz
Publikováno v:
Pilot and Feasibility Studies, Vol 9, Iss 1, Pp 1-9 (2023)
Abstract Background Emotional behavior problems (EBP) are the most common and persistent mental health issues in early childhood. Early intervention programs are crucial in helping children with EBP. Parent–child interaction therapy (PCIT) is an ev
Externí odkaz:
https://doaj.org/article/d8e4dad0d4ef48899f998e564711a5e1
Autor:
Elizabeth A. Holzhausen, Natalie Shen, Bridget Chalifour, ViLinh Tran, Zhenjiang Li, Jeremy A. Sarnat, Howard H. Chang, Dean P. Jones, Michael I. Goran, Donghai Liang, Tanya L. Alderete
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract During the first 2 years of life, the infant gut microbiome is rapidly developing, and gut bacteria may impact host health through the production of metabolites that can have systemic effects. Thus, the fecal metabolome represents a function
Externí odkaz:
https://doaj.org/article/c1a147d4df544f02b94276482c85bd03