Výsledky vyhledávání - "Dean P. J. Kavanagh"

Akademický článek

Monitoring coronary blood flow by laser speckle contrast imaging after myocardial ischaemia reperfusion injury in adult and aged mice

Autor: Juma El-Awaisi, Dean P. J. Kavanagh, Neena Kalia

Publikováno v: Frontiers in Cardiovascular Medicine, Vol 11 (2024)

IntroductionInvestigating coronary microvascular perfusion responses after myocardial infarction (MI) would aid in the development of flow preserving therapies. Laser speckle contrast imaging (LSCI) is a powerful tool used for real-time, non-contact,

Externí odkaz: https://doaj.org/article/501f41e9da1340e2bc2ecbb4c5f3443e

Zobrazit plný text záznamu

Akademický článek

Improving vasculoprotective effects of MSCs in coronary microvessels – benefits of 3D culture, sub-populations and heparin

Autor: Kobkaew Bumroongthai, Dean P. J. Kavanagh, Paul Genever, Neena Kalia

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

IntroductionOpening occluded coronary arteries in patients with myocardial infarction (MI) damages the delicate coronary microvessels through a process called myocardial ischaemia-reperfusion injury. Although mesenchymal stromal cells (MSCs) have the

Externí odkaz: https://doaj.org/article/4ef2ad825f0d4985bc53021091236e41

Zobrazit plný text záznamu

Akademický článek

Enhancing the Adhesion of Hematopoietic Precursor Cell Integrins with Hydrogen Peroxide Increases Recruitment within Murine Gut

Autor: Dean P. J. Kavanagh, Adrian I. Yemm, J. Steven Alexander, Jon Frampton, Neena Kalia

Publikováno v: Cell Transplantation, Vol 22 (2013)

Hematopoietic stem cells (HSCs) migrate to injury sites and aid in tissue repair. However, clinical success is poor and is partially due to limited HSC recruitment. We hypothesized that HSC pretreatment with H 2 O 2 would enhance their recruitment to

Externí odkaz: https://doaj.org/article/148dd56b847f481fa5a439454b92e2b2

Zobrazit plný text záznamu

Akademický článek

Modulating the Adhesion of Haematopoietic Stem Cells with Chemokines to Enhance Their Recruitment to the Ischaemically Injured Murine Kidney.

Autor: Rebecca L White, Gerard Nash, Dean P J Kavanagh, Caroline O S Savage, Neena Kalia

Publikováno v: PLoS ONE, Vol 8, Iss 6, p e66489 (2013)

Renal disease affects over 500 million people worldwide and is set to increase as treatment options are predominately supportive. Evidence suggests that exogenous haematopoietic stem cells (HSCs) can be of benefit but due to the rarity and poor homin

Externí odkaz: https://doaj.org/article/873386fc839b48389482b5b093ad0f52

Zobrazit plný text záznamu

Akademický článek

Mechanisms of adhesion and subsequent actions of a haematopoietic stem cell line, HPC-7, in the injured murine intestinal microcirculation in vivo.

Autor: Dean P J Kavanagh, Adrian I Yemm, Yan Zhao, Jon Frampton, Neena Kalia

Publikováno v: PLoS ONE, Vol 8, Iss 3, p e59150 (2013)

Although haematopoietic stem cells (HSCs) migrate to injured gut, therapeutic success clinically remains poor. This has been partially attributed to limited local HSC recruitment following systemic injection. Identifying site specific adhesive mechan

Externí odkaz: https://doaj.org/article/1b670f22e9024826834cdbcc055f41dd

Zobrazit plný text záznamu