Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Dean Margeson"'
Autor:
Meir Wetzler, John Curfman, Michael A. Caligiuri, Heiko Becker, Sebastian Schwind, Klaus H. Metzeler, Joseph O. Moore, Dean Margeson, Richard A. Larson, Kati Maharry, Susan P. Whitman, Thomas H. Carter, Maria R. Baer, William Blum, Andrew J. Carroll, Yue-Zhong Wu, Jonathan E. Kolitz, Bayard L. Powell, Kelsi B. Holland, Clara D. Bloomfield, Michael D. Radmacher, Krzysztof Mrózek, Guido Marcucci
Publikováno v:
Journal of Clinical Oncology. 29:1373-1381
Purpose To determine the frequency of TET2 mutations, their associations with clinical and molecular characteristics and outcome, and the associated gene- and microRNA-expression signatures in patients with primary cytogenetically normal acute myeloi
Autor:
Kati Maharry, Michael D. Radmacher, Claudia D. Baldus, Kelsi B. Holland, Krzysztof Mrózek, Klaus H. Metzeler, Richard A. Larson, Heiko Becker, Peter Paschka, Andrew J. Carroll, Sebastian Schwind, Dean Margeson, Christopher Hickey, Bayard L. Powell, Susan P. Whitman, Clara D. Bloomfield, Jonathan E. Kolitz, Michael A. Caligiuri, Ramiro Garzon, Guido Marcucci, Shujun Liu
Publikováno v:
Journal of Clinical Oncology. 28:5257-5264
Purpose To evaluate the prognostic significance of expression levels of a single microRNA, miR-181a, in the context of established molecular markers in cytogenetically normal acute myeloid leukemia (CN-AML), and to gain insight into the leukemogenic
Autor:
Michael D. Radmacher, Clara D. Bloomfield, Sebastian Schwind, Dean Margeson, Yue-Zhong Wu, Susan P. Whitman, Richard A. Larson, Jing Wen, Kelsi B. Holland, Meir Wetzler, Michael A. Caligiuri, Heiko Becker, Richard Stone, Klaus H. Metzeler, Joseph O. Moore, Jonathan E. Kolitz, Kati Maharry, Maria R. Baer, Thomas H. Carter, Andrew J. Carroll, Bayard L. Powell, Guido Marcucci, Krzysztof Mrózek
Publikováno v:
Blood. 116:3622-3626
The clinical impact of FLT3-internal tandem duplications (ITDs), an adverse prognostic marker in adults aged < 60 years with primary cytogenetically normal acute myeloid leukemia (CN-AML), requires further investigation in older patients. In CN-AML p
Autor:
Clara D. Bloomfield, Thomas H. Carter, Andrew J. Carroll, Michael A. Caligiuri, Meir Wetzler, Heiko Becker, Sebastian Schwind, Dean Margeson, Maria R. Baer, Susan P. Whitman, Richard A. Larson, Jonathan E. Kolitz, Michael D. Radmacher, Yue-Zhong Wu, Bayard L. Powell, Guido Marcucci, Peter Paschka, Krzysztof Mrózek, Kati Maharry
Publikováno v:
Journal of Clinical Oncology. 28:596-604
Purpose To analyze the prognostic significance of NPM1 mutations, and the associated gene- and microRNA-expression signatures in older patients with de novo, cytogenetically normal acute myeloid leukemia (CN-AML) treated with intensive chemotherapy.
Autor:
Jing Wen, Kati Maharry, Dean Margeson, Susan P. Whitman, Sandya Liyanarachchi, Li Yu, Tatiana Witte, Clara D. Bloomfield, Michael A. Caligiuri, Bjoern Hackanson, Christoph Plass, Ramana V. Davuluri, Chunhui Liu, Laura J. Rush, Shujun Liu, Guido Marcucci
Publikováno v:
Blood. 112:2013-2016
Posttranslationally modified histones and DNA hypermethylation frequently interplay to deregulate gene expression in cancer. We report that acute myeloid leukemia (AML) with an aberrant histone methyltransferase, the mixed lineage leukemia partial ta
Autor:
Dean Margeson, Michael B. Montalto, Winston W.K. Koo, Mouhanad Hammami, John B Lasekan, Chuks Nwaesei
Publikováno v:
Pediatrics. 111:1017-1023
Objective. Palm and palm olein (PO) oils are used in some infant formula fat blends to match the fatty acid profile of human milk, but their presence has been shown to lower calcium and fat absorption. We aimed to determine if the reported difference
Autor:
Yue-Zhong Wu, Heiko Becker, Jonathan E. Kolitz, Michael A. Caligiuri, Bayard L. Powell, Kati Maharry, Maria R. Baer, Guido Marcucci, Krzysztof Mrózek, Sebastian Schwind, Dean Margeson, Clara D. Bloomfield, Susan P. Whitman, Klaus H. Metzeler, Joseph O. Moore, Kelsi B. Holland, Michael D. Radmacher, Richard A. Larson, Thomas H. Carter, Andrew J. Carroll
Publikováno v:
Blood. 116(25)
BAALC and ERG expression levels are prognostic markers in younger (< 60 years) cytogenetically normal acute myeloid leukemia (CN-AML) adults; their prognostic impact in older (≥ 60 years) patients requires further investigation. We evaluated pretre
Autor:
Michael D. Radmacher, Michael A. Caligiuri, Kati Maharry, Sebastian Schwind, Dean Margeson, Bayard L. Powell, Meir Wetzler, Susan P. Whitman, Guido Marcucci, Kelsi B. Holland, Thomas H. Carter, Andrew J. Carroll, Maria R. Baer, Peter Paschka, Jonathan E. Kolitz, Yue-Zhong Wu, Clara D. Bloomfield, Joseph O. Moore, Heiko Becker, Richard A. Larson, Krzysztof Mrózek
Publikováno v:
Blood. 116(5)
We previously reported the adverse prognostic impact of Wilms tumor 1 gene (WT1) mutations in younger adult cytogenetically normal acute myeloid leukemia (CN-AML). Here, we investigated 243 older (≥ 60 years) primary CN-AML patients. WT1 mutated (W
Autor:
Meir Wetzler, Michael D. Radmacher, Maria R. Baer, Heiko Becker, Klaus H. Metzeler, Clara D. Bloomfield, Kati Maharry, Kelsi B. Holland, Bayard L. Powell, Michael A. Caligiuri, Guido Marcucci, Richard A. Larson, Sebastian Schwind, Dean Margeson, Susan P. Whitman, Jonathan E. Kolitz, Yue-Zhong Wu, Krzysztof Mrózek, Thomas H. Carter, Andrew J. Carroll
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 28(14)
Purpose To analyze the frequency and associations with prognostic markers and outcome of mutations in IDH genes encoding isocitrate dehydrogenases in adult de novo cytogenetically normal acute myeloid leukemia (CN-AML). Patients and Methods Diagnosti
Autor:
E. Eugenie Hartmann, Joan R. Jacobs, Sharon Groh-Wargo, Joanne S Szabo, David H. Adamkin, Sonja L. Connor, Vance Zemon, Marcella Castillo, Katherine A. Fitzgerald, Robert T. Hall, Jeri S. Janowsky, Patricia Mena, Gail Ross, Lynn T. Singer, Deborah L O'Connor, Terence Stephenson, Martha Neuringer, Nancy Auestad, Dean Margeson, William E. Connor, Alan Lucas
Publikováno v:
Journal of pediatric gastroenterology and nutrition. 37(4)
In a recent meta-analysis, human milk feeding of low birth-weight (LBW) infants was associated with a 5.2 point improvement in IQ tests. However, in the studies in this meta-analysis, feeding regimens were used (unfortified human milk, term formula)