Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Dean M, Talia"'
Autor:
Devy Deliyanti, Dean M. Talia, Tong Zhu, Mhairi J. Maxwell, Alex Agrotis, Jack R. Jerome, Emily M. Hargreaves, Steven Gerondakis, Margaret L. Hibbs, Fabienne Mackay, Jennifer L. Wilkinson-Berka
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
The local immune responses in the eye are attenuated to preserve sight. Surprisingly, Deliyanti et al. show that regulatory T cells (Tregs) take an active role in protecting the eye from neovascularization in oxygen-induced retinopathy, and that inte
Externí odkaz:
https://doaj.org/article/50f3675a81e5466f9c5075205f5d2ecb
Autor:
Margaret L. Hibbs, Peter van Wijngaarden, Chad Johnson, Dean M Talia, Evelyn Tsantikos, Timothy A. Gottschalk, Jennifer L. Wilkinson-Berka, Lakshanie C Wickramasinghe, Maverick Lau, Devy Deliyanti
Publikováno v:
The American Journal of Pathology. 190:1801-1812
Bronchopulmonary dysplasia (BPD) and retinopathy of prematurity (ROP) are two debilitating disorders that develop in preterm infants exposed to supplemental oxygen to prevent respiratory failure. Both can lead to lifelong disabilities, such as chroni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::827cb9dc06e5ac9d145d6410488805f4
https://doi.org/10.1016/j.ajpath.2020.05.016
https://doi.org/10.1016/j.ajpath.2020.05.016
Publikováno v:
The American Journal of Pathology. 188:805-817
Although increasing evidence indicates that endothelin-2 (Edn2) has distinct roles in tissue pathology, including inflammation, glial cell dysfunction, and angiogenesis, its role in the retina and the factors that regulate its actions are not fully u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c05ac41dce2a502827ad6d600138bcbd
https://doi.org/10.1016/j.ajpath.2017.11.009
https://doi.org/10.1016/j.ajpath.2017.11.009
Autor:
Jennifer L. Wilkinson-Berka, Evelyn Tsantikos, Maverick Lau, Lakshanie C Wickramasinghe, Devy Deliyanti, Dean M Talia, Margaret L. Hibbs
Publikováno v:
Neonatology and paediatric intensive care.
Bronchopulmonary dysplasia (BPD) and retinopathy of prematurity (ROP) are two severe disorders which arise in the lungs and eyes of preterm infants exposed to prolonged supplemental oxygen. Due to the lack of a clinically relevant animal model of sim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aab51d3f576fc8637cf3cd0c6e0bbf59
https://doi.org/10.1183/13993003.congress-2019.oa274
https://doi.org/10.1183/13993003.congress-2019.oa274
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 36:1186-1196
Objective— Although inhibitors of vascular endothelial growth factor (VEGF) provide benefit for the management of neovascular retinopathies, their use is limited to end-stage disease and some eyes are resistant. We hypothesized that retinoic acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8f71c91c45a9c1d3ab9a2f1917423ce
https://doi.org/10.1161/atvbaha.115.307080
https://doi.org/10.1161/atvbaha.115.307080
Autor:
Sih Min Tan, Jennifer L. Wilkinson-Berka, Dean M Talia, Devy Deliyanti, Judy B. de Haan, William A. Figgett
Publikováno v:
Experimental Eye Research. 136:1-8
Oxidative stress is an important contributor to glial and vascular cell damage in ischemic retinopathies. We hypothesized that ebselen via its ability to reduce reactive oxygen species (ROS) and augment nuclear factor-like 2 (Nrf2) anti-oxidants woul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9cdcc8849757ad8d0545eb39536be1f
https://doi.org/10.1016/j.exer.2015.04.015
https://doi.org/10.1016/j.exer.2015.04.015
Publikováno v:
The American journal of pathology. 188(3)
Although increasing evidence indicates that endothelin-2 (Edn2) has distinct roles in tissue pathology, including inflammation, glial cell dysfunction, and angiogenesis, its role in the retina and the factors that regulate its actions are not fully u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4479a62e39dd43364fd3ec8f85ea8ee8
https://pubmed.ncbi.nlm.nih.gov/29248456
https://pubmed.ncbi.nlm.nih.gov/29248456
Autor:
Jack R Jerome, Jennifer L. Wilkinson-Berka, Dean M Talia, Varaporn Suphapimol, Indrajeetsinh Rana, Devy Deliyanti
Publikováno v:
Experimental Eye Research. 191:107902
Microglial cells are important contributors to the neuroinflammation and blood vessel damage that occurs in ischemic retinopathies. We hypothesized that key effectors of the renin-angiotensin aldosterone system, angiotensin II (Ang II) and aldosteron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49b0ed6fc2ced3d67f51e18f6e0206a3
https://doi.org/10.1016/j.exer.2019.107902
https://doi.org/10.1016/j.exer.2019.107902
Autor:
Devy, Deliyanti, Dean M, Talia, Tong, Zhu, Mhairi J, Maxwell, Alex, Agrotis, Jack R, Jerome, Emily M, Hargreaves, Steven, Gerondakis, Margaret L, Hibbs, Fabienne, Mackay, Jennifer L, Wilkinson-Berka
Publikováno v:
Nature communications. 8(1)
Neovascular retinopathies are major causes of vision loss; yet treatments to prevent the condition are inadequate. The role of regulatory T cells in neovascular retinopathy is unknown. Here we show that in retinopathy regulatory T cells are transient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::61309654214e16fa5610b99a0cbafa95
https://pubmed.ncbi.nlm.nih.gov/29248531
https://pubmed.ncbi.nlm.nih.gov/29248531