Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Dean L. Kellogg"'
Autor:
Mitzi M. Gonzales, Valentina R. Garbarino, Erin Pollet, Juan P. Palavicini, Dean L. Kellogg Jr., Ellen Kraig, Miranda E. Orr
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 10 (2022)
Alzheimer’s disease and related dementias (ADRD) are among the top contributors to disability and mortality in later life. As with many chronic conditions, aging is the single most influential factor in the development of ADRD. Even among older adu
Externí odkaz:
https://doaj.org/article/0beaf9a2d16a4e038cddae96ddea033e
Autor:
Francesco Blasi, Stefano Aliberti, Antonio Voza, Gabriele Bongiovanni, Antonio Tonutti, Anna Stainer, Mattia Nigro, Dean L Kellogg, Anoop Nambiar, Andrea Gramegna, Marco Mantero, Francesco Amati
Publikováno v:
BMJ Open Respiratory Research, Vol 11, Iss 1 (2024)
Objectives Vasoactive drugs have exhibited clinical efficacy in addressing pulmonary arterial hypertension, manifesting a significant reduction in morbidity and mortality. Pulmonary hypertension may complicate advanced interstitial lung disease (PH-I
Externí odkaz:
https://doaj.org/article/83888c04e1cb47bc9c942bccd30079d7
Autor:
Jingzhone Ding, Alain G. Bertoni, Anthony J.A. Molina, Javed Butler, Jamie N. Justice, George E. Taffet, Scott L. Hummel, Daniel E. Forman, Flora Sam, Bret H. Goodpaster, Julio A. Chirinos, Ambarish Pandey, Barry A. Borlaug, Robert J. Mentz, Mark J. Haykowsky, Gregory D. Lewis, Marc A. Simon, Sanjiv J. Shah, Nathan K. LeBrasseur, Iraklis I. Pipinos, Dalane W. Kitzman, Dean L. Kellogg, James P. White, Roger A. Fielding, Elena Volpi
Publikováno v:
Journal of the American College of Cardiology. 78:1166-1187
Exercise intolerance (EI) is the primary manifestation of chronic heart failure with preserved ejection fraction (HFpEF), the most common form of heart failure among older individuals. The recent recognition that HFpEF is likely a systemic, multiorga
Publikováno v:
Current Molecular Biology Reports
Cellular senescence (CS) is increasingly implicated in the etiology of age-related diseases. While CS can facilitate physiological processes such as tissue repair and wound healing, senescent cells also contribute to pathophysiological processes invo
Akademický článek
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Publikováno v:
J Spinal Cord Med
Objective: Cardiovascular disease (CVD) is a leading cause of mortality in persons with SCI. While macrovascular remodeling and function after SCI is well documented, changes in the microvascular structure and function are comparably understudied, bu
Autor:
Terry Romo, Stephen R. Kraus, Che Kelly, Dean L. Kellogg, Sharon Stowe, Marsha Polk, Michelle Trbovich, Wouter Koek
Publikováno v:
Spinal Cord Ser Cases
Study design Pre-post intervention. Objectives 1. To test whether replacement of oral anticholinergic (AC) agents with mirabegron for neurogenic lower urinary tract dysfunction (NLUTD) yields improved cognitive function in older persons with spinal c
Autor:
Daniel J. MacCarthy, Jing Wang, Kalpana P. Padala, Becky Powers, Sara E. Espinoza, Chen Pin Wang, Prasad R. Padala, Dean L. Kellogg, Beverly Orsak, Rozmin Jiwani
Publikováno v:
Geriatric nursing (New York, N.Y.). 42(2)
Over one quarter of older adults in the U.S. has diabetes; and, physical activity is important for the promotion of healthy aging in this population. The purpose of this clinical demonstration project is to evaluate the effect of physical activity in
Publikováno v:
J Spinal Cord Med
Objective: Thermoregulatory dysfunction after spinal cord injury (SCI) impairs quality of life and predisposes persons to life-threatening sequela of heat-related illness (HRI) in conditions of high ambient temperature. SCI clinicians currently have
Autor:
Yubo Wu, Hanyu Liang, Terry Q. Romo, Nicolas Musi, Adriana D. Benavides, Tyler J. Curiel, Dean L. Kellogg, Wouter Koek, Jonathan Gelfond, Ellen Kraig, Martin A. Javors, Leslie A. Linehan, Laura K. Chiodo, Qianqian Liu
Publikováno v:
Experimental Gerontology. 105:53-69
Inhibition of the mechanistic target of rapamycin (mTOR) pathway by rapamycin (RAPA), an FDA-approved immunosuppressive drug used as a clinical therapy to prevent solid organ allograft rejection, enhances longevity in mice. Importantly, RAPA was effi