Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Dean Kirson"'
Autor:
Sophia Khom, Vittoria Borgonetti, Valentina Vozella, Dean Kirson, Larry Rodriguez, Pauravi Gandhi, Paula Cristina Bianchi, Angela Snyder, Roman Vlkolinsky, Michal Bajo, Christopher S. Oleata, Roberto Ciccocioppo, Marisa Roberto
Publikováno v:
Neurobiology of Stress, Vol 25, Iss , Pp 100547- (2023)
Impairments in the function of the hypothalamic-pituitary-adrenal (HPA) axis and enhanced glucocorticoid receptor (GR) activity in the central amygdala (CeA) are critical mechanisms in the pathogenesis of alcohol use disorder (AUD). The GR antagonist
Externí odkaz:
https://doaj.org/article/99beeb65eecb434d88af1339ae38c64f
Autor:
Vittoria Borgonetti, Bryan Cruz, Valentina Vozella, Sophia Khom, Michael Q. Steinman, Ryan Bullard, Shannon D’Ambrosio, Christopher S. Oleata, Roman Vlkolinsky, Michal Bajo, Eric P. Zorrilla, Dean Kirson, Marisa Roberto
Publikováno v:
Cells, Vol 12, Iss 15, p 1943 (2023)
Alcohol use disorder (AUD) and anxiety disorders are frequently comorbid and share dysregulated neuroimmune-related pathways. Here, we used our established rat model of comorbid post-traumatic stress disorder (PTSD)/AUD to characterize the interleuki
Externí odkaz:
https://doaj.org/article/f1ca53bbecf847929d0a2eb987ed9032
Autor:
Sophia Khom, Larry Rodriguez, Pauravi Gandhi, Dean Kirson, Michal Bajo, Christopher S. Oleata, Leandro F. Vendruscolo, Barbara J. Mason, Marisa Roberto
Publikováno v:
Neurobiology of Disease, Vol 164, Iss , Pp 105610- (2022)
Aberrant glucocorticoid signaling via glucocorticoid receptors (GR) plays a critical role in alcohol use disorder (AUD). Acute alcohol withdrawal and protracted abstinence in dependent rats are associated with increased GR signaling and changes in GR
Externí odkaz:
https://doaj.org/article/3609dd49c37d4a49bd8fa7e78acfae86
Autor:
Dean Kirson, Sarah A. Wolfe, Larry Rodriguez, Michael Q. Steinman, Sophia Khom, Christopher S. Oleata, Marisa Roberto
Publikováno v:
Alcohol. 109:96-97
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03b2edcf7e2f6f13118030b5ba2acbee
https://doi.org/10.1016/j.alcohol.2023.03.118
https://doi.org/10.1016/j.alcohol.2023.03.118
Autor:
Samantha R. Spierling Bagsic, Michal Bajo, Michael Q. Steinman, Sarah A. Wolfe, Eric P. Zorrilla, Ilhem Messaoudi, Suhas Sureshchandra, Dean Kirson, Christopher S. Oleata, Marisa Roberto
Publikováno v:
J Neurosci Res
Alcohol use disorder (AUD) and affective disorders are frequently comorbid and share underlying mechanisms that could be targets for comprehensive treatment. Post-traumatic stress disorder (PTSD) has high comorbidity with AUD, but comprehensive model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbd66fdee4aacbd50ee26632f7eb068f
https://doi.org/10.1002/jnr.24972
https://doi.org/10.1002/jnr.24972
Autor:
Bryan Cruz, Valentina Vozella, Benjamin A. Carper, Joy C. Xu, Dean Kirson, Shawn Hirsch, Tracy Nolen, Lauren Bradley, Katie Fain, Meg Crawford, Thomas R. Kosten, Eric P. Zorrilla, Marisa Roberto
Publikováno v:
Neuropsychopharmacology.
Post-traumatic stress disorder (PTSD) leads to enhanced alcohol drinking and development of alcohol use disorder (AUD). Identifying shared neural mechanisms might help discover new therapies for PTSD/AUD. Here, we employed a rat model of comorbid PTS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f476b5f125fc8d6cb51d70054121faa3
https://doi.org/10.1038/s41386-022-01497-w
https://doi.org/10.1038/s41386-022-01497-w
Autor:
Bryan Cruz, Ryan Bullard, Valentina Vozella, Vittoria Borgonetti, Paula C. Bianchi, Dean Kirson, Michal Bajo, Robert O. Messing, Eric P. Zorrila, Marisa Roberto
Publikováno v:
Alcohol. 109:84
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::287f0bdd0214799f2c15f773f807e8c5
https://doi.org/10.1016/j.alcohol.2023.03.072
https://doi.org/10.1016/j.alcohol.2023.03.072
Autor:
Larry Rodriguez, Dean Kirson, Sarah A. Wolfe, Reesha R. Patel, Florence P. Varodayan, Angela E. Snyder, Pauravi J. Gandhi, Sophia Khom, Roman Vlkolinsky, Michal Bajo, Marisa Roberto
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 14; Pages: 7842
Alcohol use disorder (AUD) is a chronically relapsing disease characterized by loss of control in seeking and consuming alcohol (ethanol) driven by the recruitment of brain stress systems. However, AUD differs among the sexes: men are more likely to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c503baa82e2eaa92c99a6b62f3a8e86
Autor:
Roman Vlkolinsky, Reesha R. Patel, Sarah A. Wolfe, Michal Bajo, Larry Rodriguez, Pauravi J Gandhi, Marisa Roberto, Dean Kirson, Florence P. Varodayan, Sophia Khom
Publikováno v:
Alcohol Alcohol
Aims Alcohol use disorder (AUD) is linked to hyperactivity of brain stress systems, leading to withdrawal states which drive relapse. AUD differs among the sexes, as men are more likely to have AUD than women, but women progress from casual use to bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb0329bba12788d3893d4df58bf3750c
https://doi.org/10.1093/alcalc/agab034
https://doi.org/10.1093/alcalc/agab034
Publikováno v:
Alcohol Clin Exp Res
BACKGROUND: Alcohol Use Disorder (AUD) increases brain stress systems while suppressing reward system functioning. One expression of stress system recruitment is elevated GABAergic activity in the central amygdala (CeA), which is involved in the exce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2851bcb0a2414604dcab0dd540723c93
https://doi.org/10.1111/acer.14252
https://doi.org/10.1111/acer.14252