Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Dean J. Bryant"'
Autor:
Annabel R. Minton, Lindsay D. Smith, Dean J. Bryant, Jonathan C. Strefford, Francesco Forconi, Freda K. Stevenson, Edd James, Geir Åge Løset, Ludvig A. Munthe, Andrew J. Steele, Graham Packham
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 3, Iss 1, Pp 37-49 (2022)
Aim: T-helper cells could play an important role in the pathogenesis of chronic lymphocytic leukemia (CLL), a common B-cell neoplasm. Although CLL cells can present soluble antigens targeted from the B-cell receptor to T-helper cells via major histo
Externí odkaz:
https://doaj.org/article/ac5ae262efeb47cfa557944906cc5bb4
Autor:
Beatriz Valle-Argos, Giorgia Chiodin, Dean J. Bryant, Joe Taylor, Elizabeth Lemm, Patrick J. Duriez, Philip J. Rock, Jonathan C. Strefford, Francesco Forconi, Richard W. Burack, Graham Packham, Freda K. Stevenson
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract In follicular lymphoma (FL), surface immunoglobulin (sIg) carries mandatory N-glycosylation sites in the variable regions, inserted during somatic hypermutation. These glycosylation sites are tumor-specific, indicating a critical function in
Externí odkaz:
https://doaj.org/article/0f9b4c5e32fc4b8ab9e5de05992b58d9
Autor:
Zhenghao Chen, Helga Simon-Molas, Gaspard Cretenet, Beatriz Valle-Argos, Lindsay D. Smith, Francesco Forconi, Bauke V. Schomakers, Michel van Weeghel, Dean J. Bryant, Jaco A. C. van Bruggen, Fleur S. Peters, Jeffrey C. Rathmell, Gerritje J. W. van der Windt, Arnon P. Kater, Graham Packham, Eric Eldering
Publikováno v:
Blood, 140(6), 630-643. American Society of Hematology
Chen, Z, Simon-Molas, H, Cretenet, G, Valle-Argos, B, Smith, L D, Forconi, F, Schomakers, B V, van Weeghel, M, Bryant, D J, van Bruggen, J A C, Peters, F S, Rathmell, J C, van der Windt, G J W, Kater, A P, Packham, G & Eldering, E 2022, ' Characterization of metabolic alterations of chronic lymphocytic leukemia in the lymph node microenvironment ', Blood, vol. 140, no. 6, pp. 630-643 . https://doi.org/10.1182/blood.2021013990
Chen, Z, Simon-Molas, H, Cretenet, G, Valle-Argos, B, Smith, L D, Forconi, F, Schomakers, B V, van Weeghel, M, Bryant, D J, van Bruggen, J A C, Peters, F S, Rathmell, J C, van der Windt, G J W, Kater, A P, Packham, G & Eldering, E 2022, ' Characterization of metabolic alterations of chronic lymphocytic leukemia in the lymph node microenvironment ', Blood, vol. 140, no. 6, pp. 630-643 . https://doi.org/10.1182/blood.2021013990
Altered metabolism is a hallmark of both cell division and cancer. Chronic lymphocytic leukemia (CLL) cells circulate between peripheral blood (PB) and lymph nodes (LNs), where they receive proliferative and prosurvival signals from surrounding cells