Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Dean J Welsch"'
Autor:
Dean J. Welsch, Saurabh Saha, Caroline M. Emery, Mark Namchuk, Gary DeCrescenzo, Anna Groover, Kathryn Meshaw, Ramin Samadani, Michael J. Wick, Paul Shapiro, Matthew Fitzgibbon, Gabriel Martinez-Botella, David A. Sorrell, Diane M. Boucher, Michael Hale, Jeffrey J. Roix, Alex M. Aronov, Russell R. Hoover, William Markland, Brinley F. Furey, Ursula A. Germann
(A) FACS data for UACC-62 cell line following 200nM and 2000nM treatment with BVD-523 for 24 hours. (B) Percentage of MIAPaCa2 cells in G1, S, or G2 phase of the cell cycle following 0, 24 and 48 hours of 5μM BVD-523 treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39653490bc80f75ddc2acc60a51e9d29
https://doi.org/10.1158/1535-7163.22508712
https://doi.org/10.1158/1535-7163.22508712
Autor:
Brian M. Wolpin, Scott L. Carter, Ryan B. Corcoran, William C. Hahn, Jen Jen Yeh, Nikhil Wagle, David A. Tuveson, Paul B. Shyn, Jeffrey W. Miller, Robert J. Mayer, Matthew H. Kulke, Bruce E. Johnson, Jason L. Hornick, Gad Getz, Levi A. Garraway, Charles S. Fuchs, Matthew B. Yurgelun, Dean J. Welsch, Deborah Knoerzer, Richard B. Lanman, Rebecca J. Nagy, Stuart G. Silverman, Ewa Sicinska, Geoffrey I. Shapiro, Marvin Ryou, Douglas A. Rubinson, Michael H. Rosenthal, Kimberly Perez, Anuj K. Patel, Kimmie Ng, Janet E. Murphy, Jeffrey A. Meyerhardt, Nadine J. McCleary, Kunal Jajoo, Leona A. Doyle, James M. Cleary, Thomas Clancy, Kelly P. Burke, Joseph P. St. Pierre, Heather A. Shahzade, Emily E. Van Seventer, Brandon Nadres, Annacarolina Da Silva, Ana Babic, Nelly Oliver, Karla Helvie, Kristin Anderka, Lori Marini, Devin McCabe, Emma Reilly, Marisa W. Welch, Dorisanne Ragon, Lauren K. Brais, Jaegil Kim, Srivatsan Raghavan, Mehlika Hazar-Rethinam, Arezou A. Ghazani, Richard A. Moffitt, Nicholas D. Camarda, Jonathan A. Nowak, Andrew J. Aguirre
MAF file for copy number variations identified in the cohort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a50ef08101f64b6034b9a8359c272e7a
https://doi.org/10.1158/2159-8290.22532632
https://doi.org/10.1158/2159-8290.22532632
Autor:
Dean J. Welsch, Saurabh Saha, Caroline M. Emery, Mark Namchuk, Gary DeCrescenzo, Anna Groover, Kathryn Meshaw, Ramin Samadani, Michael J. Wick, Paul Shapiro, Matthew Fitzgibbon, Gabriel Martinez-Botella, David A. Sorrell, Diane M. Boucher, Michael Hale, Jeffrey J. Roix, Alex M. Aronov, Russell R. Hoover, William Markland, Brinley F. Furey, Ursula A. Germann
Supplementary materials and methods and supplementary figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2691c8ce88b24315d90208e7f0fa7411
https://doi.org/10.1158/1535-7163.22508691.v1
https://doi.org/10.1158/1535-7163.22508691.v1
Autor:
Bob T. Li, David M. Hyman, Dean J. Welsch, Mary Varterasian, Saurabh Saha, Anna L. Groover, Caroline M. Emery, Gary A. DeCrescenzo, Sapna P. Patel, Antoni Ribas, Mario E. Lacouture, Anna M. Varghese, Richard D. Carvajal, Elizabeth Buchbinder, Keith Flaherty, Mario Sznol, Andrea Wang-Gillam, Anthony W. Tolcher, James W. Mier, Geoffrey I. Shapiro, Manish R. Patel, Vicki Keedy, Jeffrey A. Sosman, Deborah Jean Lee Wong, Filip Janku, Jeffrey R. Infante, Ryan J. Sullivan
Tumor types and molecular alterations of enrolled patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7056746bff2432eadfcb1840e1a0b9f9
https://doi.org/10.1158/2159-8290.22532095.v1
https://doi.org/10.1158/2159-8290.22532095.v1
Autor:
Dean J. Welsch, Saurabh Saha, Caroline M. Emery, Mark Namchuk, Gary DeCrescenzo, Anna Groover, Kathryn Meshaw, Ramin Samadani, Michael J. Wick, Paul Shapiro, Matthew Fitzgibbon, Gabriel Martinez-Botella, David A. Sorrell, Diane M. Boucher, Michael Hale, Jeffrey J. Roix, Alex M. Aronov, Russell R. Hoover, William Markland, Brinley F. Furey, Ursula A. Germann
In SW48 colorectal cells engineered with KRAS alleles, response to paclitaxel was unaltered.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37056904b019df912ca990e86321623e
https://doi.org/10.1158/1535-7163.22508697.v1
https://doi.org/10.1158/1535-7163.22508697.v1
Autor:
Brian M. Wolpin, Scott L. Carter, Ryan B. Corcoran, William C. Hahn, Jen Jen Yeh, Nikhil Wagle, David A. Tuveson, Paul B. Shyn, Jeffrey W. Miller, Robert J. Mayer, Matthew H. Kulke, Bruce E. Johnson, Jason L. Hornick, Gad Getz, Levi A. Garraway, Charles S. Fuchs, Matthew B. Yurgelun, Dean J. Welsch, Deborah Knoerzer, Richard B. Lanman, Rebecca J. Nagy, Stuart G. Silverman, Ewa Sicinska, Geoffrey I. Shapiro, Marvin Ryou, Douglas A. Rubinson, Michael H. Rosenthal, Kimberly Perez, Anuj K. Patel, Kimmie Ng, Janet E. Murphy, Jeffrey A. Meyerhardt, Nadine J. McCleary, Kunal Jajoo, Leona A. Doyle, James M. Cleary, Thomas Clancy, Kelly P. Burke, Joseph P. St. Pierre, Heather A. Shahzade, Emily E. Van Seventer, Brandon Nadres, Annacarolina Da Silva, Ana Babic, Nelly Oliver, Karla Helvie, Kristin Anderka, Lori Marini, Devin McCabe, Emma Reilly, Marisa W. Welch, Dorisanne Ragon, Lauren K. Brais, Jaegil Kim, Srivatsan Raghavan, Mehlika Hazar-Rethinam, Arezou A. Ghazani, Richard A. Moffitt, Nicholas D. Camarda, Jonathan A. Nowak, Andrew J. Aguirre
Treatment history for patients enrolled on the PancSeq protocol.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42b56a4b2885a7dd9c5ac333c18bd8e4
https://doi.org/10.1158/2159-8290.22532611
https://doi.org/10.1158/2159-8290.22532611
Autor:
Brian M. Wolpin, Scott L. Carter, Ryan B. Corcoran, William C. Hahn, Jen Jen Yeh, Nikhil Wagle, David A. Tuveson, Paul B. Shyn, Jeffrey W. Miller, Robert J. Mayer, Matthew H. Kulke, Bruce E. Johnson, Jason L. Hornick, Gad Getz, Levi A. Garraway, Charles S. Fuchs, Matthew B. Yurgelun, Dean J. Welsch, Deborah Knoerzer, Richard B. Lanman, Rebecca J. Nagy, Stuart G. Silverman, Ewa Sicinska, Geoffrey I. Shapiro, Marvin Ryou, Douglas A. Rubinson, Michael H. Rosenthal, Kimberly Perez, Anuj K. Patel, Kimmie Ng, Janet E. Murphy, Jeffrey A. Meyerhardt, Nadine J. McCleary, Kunal Jajoo, Leona A. Doyle, James M. Cleary, Thomas Clancy, Kelly P. Burke, Joseph P. St. Pierre, Heather A. Shahzade, Emily E. Van Seventer, Brandon Nadres, Annacarolina Da Silva, Ana Babic, Nelly Oliver, Karla Helvie, Kristin Anderka, Lori Marini, Devin McCabe, Emma Reilly, Marisa W. Welch, Dorisanne Ragon, Lauren K. Brais, Jaegil Kim, Srivatsan Raghavan, Mehlika Hazar-Rethinam, Arezou A. Ghazani, Richard A. Moffitt, Nicholas D. Camarda, Jonathan A. Nowak, Andrew J. Aguirre
PancSeq protocol gene list for CLIA-certified somatic and germline analysis from whole exome sequencing data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c23aae15e9e23b06e7e9b87205ae9ca
https://doi.org/10.1158/2159-8290.22532614.v1
https://doi.org/10.1158/2159-8290.22532614.v1
Autor:
Dean J. Welsch, Saurabh Saha, Caroline M. Emery, Mark Namchuk, Gary DeCrescenzo, Anna Groover, Kathryn Meshaw, Ramin Samadani, Michael J. Wick, Paul Shapiro, Matthew Fitzgibbon, Gabriel Martinez-Botella, David A. Sorrell, Diane M. Boucher, Michael Hale, Jeffrey J. Roix, Alex M. Aronov, Russell R. Hoover, William Markland, Brinley F. Furey, Ursula A. Germann
Body Weight (grams) over time (days) is shown for treatment groups in xenograft derived from a vemurafenib-relapsed patient.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::158fa345f7c0ca19f0a43f3b54d192ce
https://doi.org/10.1158/1535-7163.22508694
https://doi.org/10.1158/1535-7163.22508694
Autor:
Dean J. Welsch, Saurabh Saha, Caroline M. Emery, Mark Namchuk, Gary DeCrescenzo, Anna Groover, Kathryn Meshaw, Ramin Samadani, Michael J. Wick, Paul Shapiro, Matthew Fitzgibbon, Gabriel Martinez-Botella, David A. Sorrell, Diane M. Boucher, Michael Hale, Jeffrey J. Roix, Alex M. Aronov, Russell R. Hoover, William Markland, Brinley F. Furey, Ursula A. Germann
(A) Percent change compared to DMSO treated control for following treatment with ERK inhibitors BVD-523 (BVD), Vx11 (Vx), GDC-0994 (GDC), and SCH772984 (SCH) are shown for pAkt (S473), pP70 S6K (S371 S394), pS6 Ribo Prot (S240 244) and pS6 Ribo Prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a08a32d06cc8d6c9cdf51f1f588cc1c
https://doi.org/10.1158/1535-7163.22508706
https://doi.org/10.1158/1535-7163.22508706
Autor:
Bob T. Li, David M. Hyman, Dean J. Welsch, Mary Varterasian, Saurabh Saha, Anna L. Groover, Caroline M. Emery, Gary A. DeCrescenzo, Sapna P. Patel, Antoni Ribas, Mario E. Lacouture, Anna M. Varghese, Richard D. Carvajal, Elizabeth Buchbinder, Keith Flaherty, Mario Sznol, Andrea Wang-Gillam, Anthony W. Tolcher, James W. Mier, Geoffrey I. Shapiro, Manish R. Patel, Vicki Keedy, Jeffrey A. Sosman, Deborah Jean Lee Wong, Filip Janku, Jeffrey R. Infante, Ryan J. Sullivan
Pharmacokinetic data expressed in Cmax at each dose level in the dose escalation portion of the study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1df1d53c5a1c71a269d77c22156afe70
https://doi.org/10.1158/2159-8290.22532089.v1
https://doi.org/10.1158/2159-8290.22532089.v1