Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Dean J Kareemo"'
Autor:
Dean J. Kareemo, Christina S. Winborn, Samantha S. Olah, Carley N. Miller, JungMin Kim, Chelsie A. Kadgien, Hannah S. Actor-Engel, Harrison J. Ramsay, Austin M. Ramsey, Jason Aoto, Matthew J. Kennedy
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Tools for visualizing and manipulating protein dynamics in living cells are critical for understanding cellular function. Here we leverage recently available monoclonal antibody sequences to generate a set of affinity tags for labeling and m
Externí odkaz:
https://doaj.org/article/6994164957e4485a81f9f49a4d105b62
Autor:
Samantha S. Olah, Dean J. Kareemo, William C. Buchta, Brooke L. Sinnen, Carley N. Miller, Hannah S. Actor-Engel, Sara E. Gookin, Christina S. Winborn, Mason S. Kleinjan, Kevin C. Crosby, Jason Aoto, Katharine R. Smith, Matthew J. Kennedy
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113331- (2023)
Summary: Neurotransmitter receptors partition into nanometer-scale subdomains within the postsynaptic membrane that are precisely aligned with presynaptic neurotransmitter release sites. While spatial coordination between pre- and postsynaptic elemen
Externí odkaz:
https://doaj.org/article/3444965cf8894b45b28692c79eca5faf
Autor:
Harrison J. Ramsay, Sara E. Gookin, Austin M. Ramsey, Dean J. Kareemo, Kevin C. Crosby, Dominik G. Stich, Samantha S. Olah, Hannah S. Actor-Engel, Katharine R. Smith, Matthew J. Kennedy
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Postsynaptic neurotransmitter receptors and their associated scaffolding proteins assemble into discrete, nanometer-scale subsynaptic domains (SSDs) within the postsynaptic membrane at both excitatory and inhibitory synapses. Intriguingly, postsynapt
Externí odkaz:
https://doaj.org/article/0a611978cc574cd884372c1cb950f914
Autor:
Mason S. Kleinjan, William C. Buchta, Roberto Ogelman, In-Wook Hwang, Masaaki Kuwajima, Dusten D. Hubbard, Dean J. Kareemo, Olga Prikhodko, Samantha L. Olah, Luis E. Gomez Wulschner, Wickliffe C. Abraham, Santos J. Franco, Kristen M. Harris, Won Chan Oh, Matthew J. Kennedy
Publikováno v:
Neuron.
Dendritic spines can be directly connected to both inhibitory and excitatory presynaptic terminals, resulting in nanometer-scale proximity of opposing synaptic functions. While dually innervated spines (DiSs) are observed throughout the central nervo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87c5d725400726014039305b422db11e
https://pubmed.ncbi.nlm.nih.gov/36395772
https://pubmed.ncbi.nlm.nih.gov/36395772
Autor:
Aaron B. Bowen, Christina S. Winborn, Dean J Kareemo, Thomas Schwarz, Amos Gutnick, Mason S Kleinjan, Samantha L Schwartz, Ashley M. Bourke, Matthew J. Kennedy
Publikováno v:
The Journal of cell biology. 220(9)
Here we introduce zapalog-mediated endoplasmic reticulum trap (zapERtrap), which allows one to use light to precisely trigger forward trafficking of diverse integral membrane proteins from internal secretory organelles to the cell surface with single
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8663b67731fceb23935c6cfd0b702d2f
https://pubmed.ncbi.nlm.nih.gov/34241635
https://pubmed.ncbi.nlm.nih.gov/34241635
Autor:
Craig M. Irving, Joseph Conti, Joseph M. Schrader, Joseph A. Christian, Timothy J. Aballo, J. Christopher Octeau, Dean J. Kareemo, Abraham Kovoor, Jonathan A. Javitch, Jodi L. Camberg, J. Robert Lane
Most clinically available antipsychotic drugs (APDs) bind dopamine D2 receptors (D2R) at therapeutic concentrations, and it is thought that they suppress psychotic symptoms by serving as competitive antagonists of dopamine at D2R. Here, we present da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::671c676caedded477c208693fc2d86bf
https://europepmc.org/articles/PMC6462534/
https://europepmc.org/articles/PMC6462534/
